Harrison's Gastroenterology and Hepatology

Featuring the chapters on gastroenterology and hepatology that appear in Harrison`s Principles of Internal Medicine, 17e, this compact clinical companion delivers the latest knowledge in the field, backed by the scientific rigor and reliability that have defined Harrison`s. Inside you`ll find coverage that reflects the expertise of renowned editors and contributors-presented in a carry-anywhere format that makes it ideal for the classroom, the words, or exam/certification preparation.

The authority of Harrison's in a handy, full-color paperback devoted exclusively to Gastroenterology and Hepatology

Featuring the chapters on Gastroenterology and Hepatology that appear in the landmark Harrison's Principles of Internal Medicine, 17e, this compact clinical companion delivers all the latest knowledge in the field, backed by the scientific rigor and reliabilty that has defined Harrison's.

You'll find coverage that reflects the expertise of renowned editors and contributors -- presented in a carry-anywhere format that makes it ideal for the classroom, the wards, or the point of care. With its ease of use, indispensable diagnosis-speeding guidelines, and acclaimed state-of-the-art strategies, Harrison's Gastroenterology and Hepatology is a must for students and clinicians alike.

Harrison's Gastroenterology and Hepatology delivers:

• All the relevant chapters from Harrison's Principles of Internal Medicine, 17e
• A complete chapter from the acclaimed Harrison's DVD
• Content updates and new developments
• Reference updates
• 140+ questions and answers from Harrison's Principles of Internal Medicine Self-Assessment and Board Review, 17e
• An update on H1N1

Everything you would expect from Harrison's tailored to your specialty
Cardinal Manifestations of Gastrointestinal Disease;Evaluation of the Patient with Alimentary Tract Symptoms;Disorders of the Alimentary Tract;Infections of the Alimentary Tract;Evaluation of the Patient with Liver Disease;Disorders of the Liver and Biliary Tree;Liver Transplantation.

The Harrison’s specialty series is written by the same world-renowned author team who brought you Harrison’s Principles of Internal Medicine, 17e:
Anthony S. Fauci, MD; Eugene Braunwald, MD; Dennis L. Kasper, MD; Stephen L. Hauser, MD; Dan L. Longo, MD; J. Larry Jameson, MD, PhD; Joseph Loscalzo, MD, PhD

This authority of Harrison's in a handy, full-color paperback devoted exclusively to Gastroenterology and Hepatology. Featuring the chapters on Gastroenterology and Hepatology that appear in the landmark "Harrison's Principles of Internal Medicine, 17/e", this compact clinical companion delivers all the latest knowledge in the field, backed by the scientific rigor and reliability that has defined Harrison's. You'll find coverage that reflects the expertise of renowned editors and contributors - presented in a carry-anywhere format that makes it ideal for the classroom, the wards, or the point of care. With its ease of use, indispensable diagnosis-speeding guidelines, and acclaimed state-of-the-art strategies, "Harrison's Gastroenterology and Hepatology" is a must for students and clinicians alike. "Harrison's Gastroenterology and Hepatology" delivers: complete coverage of need-to-know gastroenterology and hepatology topics, including cardinal manifestations of disease, differential diagnosis and diagnostic evaluation, management of diseases and disorders, and obesity, nutrition, and eating disorders; references updated since the publication of "HPIM, 17/e"; content from the acclaimed Harrison's DVD in print form, including a complete atlas of liver disease; 58 chapters written by physicians who have made seminal contributions to the body of knowledge in their areas of expertise; integration of pathophysiology with clinical management topics in each of the disease-oriented chapters; 140 high-yield questions and answers drawn from "Harrison's Principles of Internal Medicine Self-Assessment and Board Review, 17/e"; and, helpful appendix of laboratory values of clinical importance. This title offers everything you would expect from Harrison's tailored to your specialty: Cardinal Manifestations of Gastrointestinal Disease; Evaluation of the Patient with Alimentary Tract Symptoms; Disorders of the Alimentary Tract; Infections of the Alimentary Tract; Evaluation of the Patient with Liver Disease; Disorders of the Liver and Biliary Tree; and, Liver Transplantation. The Harrison's specialty series is written by the same world-renowned author team who brought you "Harrison's Principles of Internal Medicine, 17/e": Anthony S. Fauci, MD; Eugene Braunwald, MD; Dennis L. Kasper, MD; Stephen L. Hauser, MD; Dan L. Longo, MD; J. Larry Jameson, MD, PhD; and, Joseph Loscalzo, MD, PhD.

Contributors		ix
Preface		xiii
SECTION I CARDINAL MANIFESTATIONS OF GASTROINTESTINAL DISEASE
1 Abdominal Pain		2	(6)
William Silen
2 Oral Manifestations of Disease		8	(13)
Samuel C. Durso
3 Atlas of Oral Manifestations of Disease		21	(6)
Samuel C. Durso
Janet A. Yellowitz
Jane C. Atkinson
4 Dysphagia		27	(6)
Raj K. Goyal
5 Nausea, Vomiting, and Indigestion		33	(9)
William L. Hasler
6 Diarrhea and Constipation		42	(16)
Michael Camilleri
Joseph A. Murray
7 Weight Loss		58	(4)
Carol M. Reife
8 Gastrointestinal Bleeding		62	(6)
Loren Laine
9 Jaundice		68	(9)
Daniel S. Pratt
Marshall M. Kaplan
10 Abdominal Swelling and Ascites		77	(7)
Robert M. Glickman
Roshini Rajapaksa
SECTION II EVALUATION OF THE PATIENT WITH ALIMENTARY TRACT SYMPTOMS
11 Approach to the Patient with Gastrointestinal Disease		84	(10)
William L. Hasler
Chung Owyang
12 Gastrointestinal Endoscopy		94	(18)
Louis Michel Wong-Kee-Song
Mark Topazian
SECTION III DISORDERS OF THE ALIMENTARY TRACT
13 Diseases of the Esophagus		112	(13)
Raj K. Goyal
14 Peptic Ulcer Disease and Related Disorders		125	(27)
John Del Valle
15 Disorders of Absorption		152	(22)
Henry J. Binder
16 Inflammatory Bowel Disease		174	(22)
Sonia Friedman
Richard S. Blumberg
17 Irritable Bowel Syndrome		196	(7)
Chung Owyang
18 Diverticular Disease and Common Anorectal Disorders		203	(10)
Susan L. Gearhart
19 Mesenteric Vascular Insufficiency		213	(5)
Susan L. Gearhart
20 Acute Intestinal Obstruction		218	(4)
Susan L. Gearhart
William Silen
21 Acute Appendicitis and Peritonitis		222	(6)
Susan L. Gearhart
William Silen
SECTION IV INFECTIONS OF THE ALIMENTARY TRACT
22 Acute Infectious Diarrheal Diseases and Bacterial Food Poisoning		228	(10)
Joan R. Butterton
Stephen B. Calderwood
23 Clostridium Difficile-Associated Disease, Including Pseudomembranous Colitis		238	(6)
Dale N. Gerding
Stuart Johnson
24 Intraabdominal Infections and Abscesses		244	(9)
Miriam J. Baron
Dennis L. Kasper
25 Helicobacter Pylori Infections		253	(7)
John C. Atherton
Martin J. Blaser
26 Salmonellosis		260	(10)
David A. Pegues
Samuel I. Miller
27 Shigellosis		270	(6)
Philippe Sansonetti
Jean Bergounioux
28 Infections Due to Campylobacter and Related Species		276	(5)
Martin J. Blaser
29 Cholera and Other Vibrioses		281	(8)
Matthew K. Waldor
Gerald T. Keusch
30 Viral Gastroenteritis		289	(7)
Umesh D. Parashar
Roger I. Glass
31 Amebiasis and Infection with Free-Living Amebas		296	(8)
Sharon L. Reed
32 Protozoal Intestinal Infections and Trichomoniasis		304	(8)
Peter F. Weller
33 Intestinal Nematodes		312	(10)
Peter F. Weller
Thomas B. Nutman
SECTION V EVALUATION OF THE PATIENT WITH LIVER DISEASE
34 Approach to the Patient with Liver Disease		322	(10)
Marc Ghany
Jay H. Hoofnagle
35 Evaluation of Liver Function		332	(8)
Daniel S. Pratt
Marshall M. Kaplan
SECTION VI DISORDERS OF THE LIVER AND BILIARY TREE
36 The Hyperbilirubinemias		340	(9)
Allan W. Wolkoff
37 Acute Viral Hepatitis		349	(29)
Jules L. Dienstag
38 Toxic and Drug-Induced Hepatitis		378	(12)
Jules L. Dienstag
39 Chronic Hepatitis		390	(25)
Jules L. Dienstag
40 Alcoholic Liver Disease		415	(4)
Mark E. Mailliard
Michael E Sorrell
41 Cirrhosis and Its Complications		419	(15)
Bruce R. Bacon
42 Genetic, Metabolic, and Infiltrative Diseases Affecting the Liver		434	(5)
Bruce R. Bacon
43 Diseases of the Gallbladder and Bile Ducts		439	(19)
Norton J. Greenberger
Gustav Paumgartner
SECTION VII LIVER TRANSPLANTATION
44 Liver Transplantation		458	(14)
Jules L. Dienstag
Raymond T. Chung
SECTION VIII DISORDERS OF THE PANCREAS
45 Approach to the Patient with Pancreatic Disease		472	(7)
Phillip P. Toskes
Norton J. Greenberger
46 Acute and Chronic Pancreatitis		479	(21)
Norton J. Greenberger
Phillip P. Toskes
SECTION IX NEOPLASTIC DISEASES OF THE GASTROINTESTINAL SYSTEM
47 Gastrointestinal Tract Cancer		500	(17)
Robert J. Mayer
48 Tumors of the Liver and Biliary Tree		517	(11)
Brian I. Carr
49 Pancreatic Cancer		528	(5)
Yu Jo Chua
David Cunningham
50 Endocrine Tumors of the Gastrointestinal Tract and Pancreas		533	(21)
Robert T. Jensen
SECTION X NUTRITION
51 Nutritional Requirements and Dietary Assessment		554	(8)
Johanna Dwyer
52 Vitamin and Trace Mineral Deficiency and Excess		562	(15)
Robert M. Russell
Paolo M. Suter
53 Malnutrition and Nutritional Assessment		577	(9)
Douglas C. Heimburger
54 Enteral and Parenteral Nutrition Therapy		586	(14)
Bruce R. Bistrian
David F. Driscoll
SECTION XI OBESITY AND EATING DISORDERS
55 Biology of Obesity		600	(10)
Jeffrey S. Flier
Eleftheria Maratos-Flier
56 Evaluation and Management of Obesity		610	(9)
Robert F. Kushner
57 Eating Disorders		619	(7)
B. Timothy Walsh
58 The Metabolic Syndrome		626	(9)
Robert H. Eckel
Appendix Laboratory Values of Clinical Importance		635	(20)
Alexander Kratz
Michael A. Pesce
Daniel J. Fink
Review and Self-Assessment		655	(48)
Charles Wiener
Gerald Bloomfield
Cynthia D. Brown
Joshua Schiffer
Adam Spivak
Index		703

Editors: Dan L. Longo, MD Scientific Director, National Institute on Aging National Institutes of Health Bethesda and Baltimore, MD Anthony S. Fauci, MD Chief, Laboratory of Immunoregulation Director, National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda, MD Associate Editor: Carol A. Langford, MD, MHS Associate Professor of Medicine Cleveland Clinic Cleveland, OH