Bioenergetics 3rd edition [Pehme köide]

(Uuem väljaanne: 9780123884251)
(Buck Institute, Novato, California, U.S.A.), (University of Oxford, U.K.)
  • Formaat: Paperback / softback, 288 pages, kõrgus x laius x paksus: 244x171x16 mm, kaal: 720 g, b&w and colour figures
  • Ilmumisaeg: 03-Jul-2002
  • Kirjastus: Academic Press Inc
  • ISBN-10: 0125181213
  • ISBN-13: 9780125181211 (Uuem väljaanne: 9780123884251)
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  • Formaat: Paperback / softback, 288 pages, kõrgus x laius x paksus: 244x171x16 mm, kaal: 720 g, b&w and colour figures
  • Ilmumisaeg: 03-Jul-2002
  • Kirjastus: Academic Press Inc
  • ISBN-10: 0125181213
  • ISBN-13: 9780125181211 (Uuem väljaanne: 9780123884251)
Teised raamatud teemal:
Extensively revised and updated, this text provides current, accurate information on chemiosmotic theory and membrane bioenergetics. Covers the many newly determined protein structures such as ATP synthase and the two photosystems of photosynthesis, that provide molecular insight into chemiosmotic energy transduction, as well as reviewing major advances in the role of the mitochondria in the life and death of the cell. Includes an appendix listing protein structure resources and new color plates and drawings. Annotation c. Book News, Inc., Portland, OR (booknews.com)

This new edition of Bioenergetics presents a clear and up-to-date explanation of the chemiosmotic theory and covers mitochondria, bacteria, and chloroplasts. It takes account of the many newly determined structures, such as ATP synthase and the two photosystems of photosynthesis, that provide molecular insight into chemiosmotic energy transduction. This edition includes additional color figures of protein structures and many newly drawn illustrations designed to enable the reader to grasp the fundamental insights that are derived from knowing the structure. Every chapter has been extensively revised and updated and a new chapter on the study of the bioenergetics of mitochondria in the intact cell is included to satisfy the enormous interest in this topic. Written for students and researchers alike, this book is the most current text on the chemiosmotic theory and membrane bioenergetics available.

Key Features
* Chapter on the study of bioenergetics of mitochondria in the intact cell
* Appendix listing protein structure resources
* Additional colour plates of protein structures
* Many newly drawn illustrations
* Website

Arvustused

"Not only is Bioenergetics 3 comprehensive, but the material is presented in a reassuringly accessible form. ...this text is supremely successful." -THE BIOCHEMIST (December 2003) "Bioenergetics 3 is a worthy successor to the second edition, and one that I can enthusiastically recommend." -Aubrey D.N.J. de Grey University of Cambridge for MITOCHONDRION (2002)

Muu info

Key Features * Chapter on the study of bioenergetics of mitochondria in the intact cell * Appendix listing protein structure resources * Additional colour plates of protein structures * Many newly drawn illustrations * Website
Preface ix
Note to the reader xiii
Glossary xv
Chemiosmotic Energy Transduction
3(14)
Introduction
3(1)
The chemiosmotic theory: fundamentals
3(4)
The basic morphology of energy-transducing membranes
7(7)
Overview
14(3)
Ion Transport Across Energy-Conserving Membranes
17(14)
Introduction
17(1)
The classification of ion transport
17(4)
Bilayer-mediated transport
21(4)
Protein-catalysed transport
25(1)
Swelling and the co-ordinate movement of ions across membranes
26(5)
Quantitative Bioenergetics: The Measurement of Driving Forces
31(26)
Introduction
31(2)
Gibbs energy and displacement from equilibrium
33(7)
Oxidation-reduction (redox) potentials
40(6)
Ion electrochemical potential differences
46(1)
Photons
47(1)
Bioenergetic interconversions and thermodynamic constraints on their stoichiometries
48(2)
The equilibrium distributions of ions, weak acids and weak bases
50(2)
Membrane potentials, diffusion potentials, Donnan potentials and surface potentials
52(5)
The Chemiosmotic Proton Circuit
57(32)
Introduction
57(2)
The measurement of protonmotive force
59(7)
The stoichiometry of proton extrusion by the respiratory chain
66(2)
The stoichiometry of proton uptake by the ATP synthase
68(1)
Proton current and respiratory control
69(4)
Proton conductance
73(4)
Mitochondrial respiration rate and metabolic control analysis
77(4)
Overall parameters of energy transduction
81(2)
Reversed electron transfer and the proton circuit driven by ATP hydrolysis
83(2)
ATP synthesis driven by an artificial protonmotive force
85(1)
Kinetic competence of Δp in the proton circuit
86(1)
Light-dependent ATP synthesis by bovine heart ATP synthase
87(2)
Respiratory Chains
89(68)
Introduction
89(1)
Components of the mitochondrial respiratory chain
89(6)
The sequence of redox carriers in the respiratory chain
95(4)
The mechanism of electron transfer
99(6)
Proton translocation by the respiratory chain: `loops', `conformational pumps' or both?
105(2)
Complex I (NADH-UQ oxidoreductase)
107(4)
Delivering electrons to ubiquinone without proton translocation
111(3)
Ubiquinone and complex III (bc1 or UQ-cyt c oxidoreductase)
114(5)
Cytochrome c and complex IV (cytochrome c oxidase; ferrocytochrome c: O2 oxidoreductase)
119(7)
Overall proton and charge movements catalysed by the respiratory chain: correlation with the P/O ratio
126(1)
Superoxide production by complexes I and III
127(2)
Oxidative stress
129(1)
The nicotinamide nucleotide transhydrogenase
130(1)
Electron transport in mitochondria of non-mammalian cells
131(3)
Bacterial respiratory chains
134(23)
Photosynthetic Generators of Protonmotive Force
157(38)
Introduction
157(2)
The light reaction of photosynthesis in Rhodobacter sphaeroides and related organisms
159(9)
The generation by illumination or respiration of Δp in photosynthetic bacteria
168(3)
The electron-transfer and light-capture pathway in green plants and algae
171(15)
Bacteriorhodopsin and halorhodopsin
186(9)
The Atp Synthase
195(24)
Introduction
195(1)
F1 and F0
195(3)
The subunits of the F1.F0 ATPase
198(1)
The structure of F1.F0
199(5)
Enzymology of ATP synthase
204(6)
Relating the structure to function for ATP synthase
210(6)
Non-thermodynamic regulation of the ATP synthase
216(1)
Proton translocation by other ATPases and pyrophosphatases
216(3)
Metabolite and Ion Transport
219(30)
Introduction
219(1)
Mitochondrial cation transporters
220(5)
Mitochondrial metabolite transporters
225(4)
The transfer of electrons from cytoplasmic NADH to the respiratory chain
229(1)
The phosphate and adenine nucleotide transporters
230(2)
The uncoupling protein family
232(2)
Bacterial transport
234(12)
Transport (movement) of bacterial cells
246(1)
Transport of macromolecules across bacterial membranes
247(2)
Mitochondria in the Cell
249(22)
Introduction
249(2)
Monitoring Δψm and ATP synthesis in intact cells
251(4)
Mitochondria and cellular Ca2+ homeostasis
255(3)
Mitochondria and programmed cell death
258(3)
Mitochondria and necrotic cell death
261(2)
The Mitochondrial genome
263(1)
Import and assembly of Mitochondrial proteins
264(2)
Mitochondrial genetic diseases
266(2)
Mitochondrial involvement in neurodegenerative diseases
268(3)
References 271(12)
Appendix: Protein structures 283(4)
Index 287