Section 1.General trends, principles, and materials
1. Latest trends in breast reconstruction
2. The biological rationale for oncoplastic surgical procedures
3. Biological reactions to reconstructive materials. Editorial Commentary. Section
2. Patient selection - breast conserving surgery or mastectomy? 4.Oncological considerations
5. Reconstructive perspectives
6. Patients' perspectives. Editorial Commentary.
7. Pre-operative radiological assessment
8. Oncological parenchymal resection
9. Intra-operative assessment. Editorial Commentary. Section
3. Breast conserving surgery and partial breast reconstruction (oncoplastic repair)
10. Timing of oncoplastic repair
11. Immediate repair before radiotherapy
12. Positive permanent surgical margins (re-excision or completion mastectomy)?
13. Delayed oncoplastic repair - before radiotherapy
14. Delayed oncoplastic repair - after radiotherapy. Editorial Commentary. Section
4. Skin-preserving mastectomy
15. Mastectomy and whole breast reconstruction: skin-sparing versus nipple-sparing mastectomy
16. Nipple-sparing mastectomy. Editorial Commentary. Section
5. Mastectomy and whole breast reconstruction (timing and patient selection)
17. Timing of reconstruction. Editorial Commentary.
18. How to choose the optimal method of whole breast reconstruction. Editorial Commentary. Section
6. Mastectomy and whole breast reconstruction (methods and techniques)
19. Implant-based whole breast reconstruction (without irradiation)
20. Implant-based whole breast reconstruction (with irradiation)
21. Fat-grafting exclusively for whole breast reconstruction. Editorial Commentary
22. Standard autologous tissue flaps for whole breast reconstruction. Editorial Commentary
23. Advanced autologous tissue flaps for whole breast reconstruction. Editorial Commentary. Section
7. Revisional breast reconstruction (following both partial and whole breast reconstruction)
24. Breast revision following breast conservation and oncoplastic repair
25. Breast revision after implant-based breast reconstruction
26. Breast revision after mastectomy, whole breast reconstruction, and postmastectomy radiation therapy. Editorial Commentary. Section
8. Techniques for delivery of radiotherapy
27. Partial or whole breast radiotherapy after breast conserving surgery?
28. Postmastectomy radiotherapy after whole breast reconstruction
29. Partial breast radiotherapy after partial mastectomy 30.Whole breast radiotherapy (boost) after partial mastectomy. Editorial Commentary. Section
9. Techniques for lymph node transfer
31. Transfer of lymph node tissue. Section
10. Nipple-areola complex reconstruction. Editorial Commentary. Section
33. The Modern Specialist Breast Surgeon
34. Breast surgical training. Editorial Commentary.
Professor John Benson is a Consultant Breast Surgeon in the Cambridge Breast Unit at Addenbrooke's Hospital, Cambridge, UK. He received his basic medical degree from Oxford University Clinical School and has been awarded doctorates from both Oxford and Cambridge Universities [ DM (Oxon); MD (Cantab)]. He was a research fellow at The Royal Marsden Hospital and Institute of Cancer Research, London and undertook internships both at the Royal Marsden Hospital in Surrey and the Chelsea and Westminster Hospital, London, UK. Further experience was gained in management of breast diseases as Visiting Professor at the New York Hospital - Cornell Medical Centre. Professor Benson is a Fellow of Selwyn College, Cambridge where he is also Director of Clinical Studies, Associate Lecturer, University of Cambridge and Professor of Applied Surgical Sciences at Anglia Ruskin University, Cambridge, UK. He is a member of the Panel of Examiners, Intercollegiate MRCS Examination (Royal College of Surgeons of Edinburgh) and was appointed a Regional Breast Tutor by The Royal College of Surgeons of England. He is a Fellow of the Royal College of Surgeons of England, a Fellow of the Royal College of Surgeons of Edinburgh and a member of the British Breast Group. His clinical practice is devoted entirely to patients with breast diseases and current research interests include investigation of a fluorescent navigation system for sentinel lymph node detection in early breast cancer patients. He has published three papers in the past 3 years on this topic - all in American journals and one of these a leading commentary summarizing where we are and where we are going with this technology (Annal of Surgical Oncology). Professor Benson is principle investigator for two national breast cancer trials (POSNOC and MarginProbe) and regularly acts as reviewer for major grant giving bodies (Cancer Research UK, Medical Research Council, Breast Cancer Now and NIHR). Professor Benson has published widely in the field of breast disease in general (>140 publications) and co-ordinated or written articles for leading journals including The Lancet and The Lancet Oncology, Annals of Surgery, British Journal of Surgery, Surgical Clinics of North America and Breast Diseases Quarterly. He has also contributed numerous book chapters and presented papers at major international meetings. He is author and editorial consultant for the breast module of PIER (American College of Physicians) and a Module Lead for the Masters in Oncoplastic Breast Surgery (E-Learning) (Royal College of Surgeons of England and University of East Anglia) [ Gold Award for e-learning 2013]. In addition, he is co-editing the third edition of the text "Oncoplastic and Reconstructive Management of the Breast" with colleagues from the United States and Italy and this should be ready for publication in early 2018. Professor Benson is ranked amongst the top 0.18% of world's breast cancer experts and won First Prize in the Oncology Section of BMA Medical Book Awards (2013). Over the past 3 years Professor Benson has undertaken invited speaker presentations in the United States, India, Brazil, Japan, Kuwait, Italy and Spain. In September 2015, he visited the University of Pernambuco in Brazil (Faculdade de Ciencias Medicas) where he gave a memorial lecture to his former Professor and mentor Antonio Figueira Filho who was a pioneer of breast surgery in South America. He is a former member of the Planning Committee for the San Antonio Breast Cancer Symposium which is the world's premier breast cancer meeting with >8000 attendees from 100 countries outside the United States of America. He was Visiting Professor at the University of Texas, Health Sciences Centre at San Antonio in December 2016 and had the honour of being invited to deliver the Grand Round Lecture (Department of Surgery). He was elected to the Executive Board of the Association of Breast Surgery (United Kingdom) as an Ordinary Trustee in September 2016. He is currently co-convener for the Advanced Skills in Breast Disease Course at the Royal College of Surgeons of England. Maurizio Nava achieved his Bachelor of Medicine and Surgery at the University of Milan in 1977. He majored in oncology in 1980 and general surgery in 1986. In 1993, he then majored in plastic and reconstructive surgery. Since graduating he worked at the Istituto Nazionale dei Tumori in Milan and from 1997 till 2014 as Director of the Plasic Surgery Unit. As Adjunct Professor - School of Specialization in Plastic Surgery, University of Milan and from 2017 University of Genova, he participates in national and international studies on implants, ADMs, fat cells and microsurgidjunctcal flaps in oncoplastic breast surgery and breast aesthetic surgery. He was President of the Oncological Reconstructive School a NOT for PROFIT, and from 2016 he is Honorary President of G.Re.Ta (Group for Reconstructive and Therapeutic Advancement) that is proposing updates to the international multidisciplinary field of oncoplastic reconstructive and aesthetic breast surgery, and an exchange of ideas with patients. He is author and co-author of more than 150 publications in Italian, English and Spanish on oncological surgery, reconstructive and aesthetic surgery of the breast. He is author of five books on ocncoplastic, reconstructive and aesthetic surgery of the breast and author of many chapters in other books. He has organized several international conferences concerning both reconstructive and aesthetic surgery of the breast. He and his team are dedicated to the surgery of the breast from tumour to reconstruction and to the aesthetic outcome and body contouring. He introduced new surgical techniques both in mastectomy and reconstruction and aesthetic breast surgery. Steven J. Kronowitz is a world-renowned expert in the field of breast reconstruction and is best known for his expertise in oncology-related breast reconstruction, radiation-related breast reconstruction, and oncoplastic surgery. He is known internationally for his expertise in multidisciplinary-breast cancer care and has developed numerous treatment approaches, techniques, and algorithms that are used worldwide in the care of patients with breast cancer. Besides publishing numerous landmark publications in peer-reviewed journals, Dr. Kronowitz edits his own international textbooks with contributions from the recognized world experts in multidisciplinary breast care. Dr. Kronowitz has published extensively and lectures both nationally and internationally. He is also a basic science researcher focusing on mechanisms of DNA injury and repair after radiation therapy, cell-to-cell interaction and crosstalk, and vascular-stromal and stem cell interaction and transplantation. Dr. Kronowitz is currently the lead surgeon at Kronowitz Plastic Surgery, an international practice of plastic surgery based in Houston, Texas. Dr. Kronowitz was a former professor with tenure, until August 2015, at the world-renowned University of Texas MD Anderson Cancer Center for 15 years. He has trained more than 250 residents and fellows in plastic surgery. He has, since 2012, been consistently awarded "Top Doctor" by U.S. News & World Report, Castle Connelly Top Doctors, Vitals Patients' Choice, American Registry Compassionate Doctor, America's Leading Expert Recognition, and Houston Chronicle's MedCity October 2016, Houston's 200+ Top Doctors The Best Physicians in 45 Specialties. He is also a winner of the Cosmetic Surgery Award, 2018 Cosmetic Surgery & Health Magazine; the 2018 Top Plastic Surgeon in Houston, International Association of Healthcare Professionals; the 2018 Superdoctors, peer-nominated by the Blue Ribbon Panel Review; the 2018 Leading Physicians of the World, spotlighted in Renown Publication; and the New York Times (National Edition), March 3, 2018, Top Cosmetic Surgeons in America. Dr. Kronowitz is a member of the American Society of Plastic Surgeons; American Association of Plastic Surgeons; American Society of Reconstructive Microsurgery; American Society of Aesthetic Plastic Surgeons; and is a Fellow of the American College of Surgeons. He serves on the editorial board of both Plastic and Reconstructive Surgery and Plastic and Reconstructive Surgery - Global Open. He has published more than 100 peer-reviewed publications in the most prestigious surgical journals. Many of these publications were landmark studies in oncology-related breast reconstruction. He travels as an invited lecturer at the most prestigious surgical conferences, medical schools, and hospitals, teaching the techniques he has developed to other plastic surgeons worldwide.