Biocatalysis in Green Solvents offers a pragmatic overview and instruction in biocatalysis and enzymology of green solvents for sustainable industries and medicine, running from concept to application. Here, international experts in the field discuss structure-function relationships of enzymes in ionic liquids (ILs) and examine how enzymes act as selective catalysts for fine biochemical synthesis in non-aqueous environments. Several integral green biochemical processes of biocatalytic transformation and pure product separation are described in detail.
Application focused chapters discuss the role of biocatalysis in creating and implementing deep eutectic solvents, biomass derived solvents, sub and supercritical fluids, carbon dioxide biphasic systems, and enzymatic membrane reactors, as well as applying these biocatalytic processes in drug discovery and production.
- Examines the structure-function relationships of enzymes in ionic liquids and biocatalytic processes for various applications across industry and medicine
- Includes clear instruction in core green biochemical processes—of (bio)catalytic transformation—and pure product separation
- Features chapter contributions from international experts across academia and industry
1. Preface
2. Foreword
3. Non-conventional biocatalysis: From organic solvents to Green Solvents
4. Synthesis and characterization of Ionic Liquids
5. Biocatalysis and Green Metrics in Sustainable Chemistry
6. Ionic liquids in biocatalytic organic synthesis
7. Ionic liquids in protein refolding
8. Stability and Stabilization of biocatalyst by ILs
9. Improved Biocatalysts for Green processes
10. Clean Biocatalysis in Sponge-Like Ionic Liquids
11. Oxidoreductases in ionic liquids and Deep eutectic Solvents (DESs) for organic chemistry
12. Potential roles for ionic liquid assisted biocatalysis in a low carbon future
13. Biocatalysis in ABS systems based on ILs
14. Biotransformations of carbohydrates in ILs
15. Biocatalysis in biomass derived solvents
16. Ionic liquids for biomass biotransformations
17. Biocatalysis in sub and supercritical fluids
18. Supported ionic liquids for biocatalysis
19. Biocatalytic processes in ionic liquids/supercritical carbon dioxide biphasic systems
20. Enzymatic membrane reactors and non-conventional solvents
21. Ionic Liquids for Biopolymer Extraction and Processing
22. Application of Ionic Liquids in Pharmaceutics and Medicine
23. Industrial application of Ionic Liquids
Pedro Lozano is full time professor in Biochemistry and Molecular Biology at the University of Murcia (Spain). He obtained his Bachelor of Science (Chemistry) at the University of Murcia in 1984, and his PhD in Science (Chemistry) at the same University in 1988. Between 1990 and 1991, he spent two years of postdoctoral training at the National Institut of Applied Sciences (INSA)-Toulouse (France). In 1993, he returned to the Faculty of Chemistry of the University of Murcia (Spain) as Associate Professor of Biochemistry and Molecular Biology, being finally promoted to Full Professor in 2004. Between, he served as Vice-Dean (1996-2014), and Dean (2014-2022) at the Faculty of Chemistry of the University of Murcia. He has also been Visiting Professor at the Universities of Rennes (France, 2002), Bordeaux (France-2013) and Universidade do Rio Grade do Sul-Porto Alegre (Brazil, 2019). His research activity has always been related to Green and Sustainable Chemistry, focusing mainly to applied biocatalysts in ionic liquids and supercritical fluids for the development of green and sustainable chemical processes. He is the author of more than 140 publications (i.e. research papers, reviews, book chapters, etc.), and more than 200 scientific contributions in National and International Congresses. He obtained the 7th IQS-European Award of Enzyme Technology (2003), Fellow of the Royal Society of Chemistry (2017), Spanish ANQUE National Award (2020). As Dean of the Faculty of Chemistry of the University of Murcia, Prof. Lozano received the Gold Medal of the Region of Murcia awarded to that Faculty in 2015, and has built of the world's largest Periodic Table on the main facade of that Faculty in 2017, being an IUPAC icon during the International Year of the Periodic Table in 2019.
He has been the promoter of the foundation of the Green Chemistry Division of the Spanish Royal Society of Chemistry in 2024, being the actual President.
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