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E-raamat: Computational Methods in Molecular Imaging Technologies

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This book highlights the experimental investigations that have been carried out on magnetic resonance imaging and computed tomography (MRI & CT) images using state-of-the-art Computational Image processing techniques, and tabulates the statistical values wherever necessary. In a very simple and straightforward way, it explains how image processing methods are used to improve the quality of medical images and facilitate analysis. It offers a valuable resource for researchers, engineers, medical doctors and bioinformatics experts alike.

1 Introduction
1(8)
1.1 Introduction to Medical Imaging
1(1)
1.2 Medical Imaging Overview
1(1)
1.3 Molecular Imaging and Its Modalities
2(3)
1.4 Medical Image Reconstruction
5(1)
1.5 Types of Image Reconstruction
6(3)
2 Artifacts Correction in MRI Images
9(20)
2.1 Existing Methods
9(1)
2.1.1 Disadvantages of Ultra-echo Time Imaging (UTE)
9(1)
2.1.2 Disadvantages of Sweep Imaging with Fourier Transform
9(1)
2.1.3 Disadvantages of Water- and Fat-suppressed Proton Projection MRI
10(1)
2.1.4 Disadvantages of ZTE Imaging Without Excitation Profile
10(1)
2.2 Implemented Method
10(1)
2.3 Process Diagram
10(1)
2.4 Model as an Inverse Problem
11(1)
2.5 NUFFT Operator
12(3)
2.5.1 Features of NUFFT
14(1)
2.5.2 Non-uniform FFT Algorithm
14(1)
2.6 Quadratic Phase-Modulated RF Pulse Excitation
15(1)
2.6.1 Hard RF Phase Modulation
16(1)
2.7 Excitation Profile Measurement
16(1)
2.8 Pointwise Encoding Time Reduction with Radial Acquisition (PETRA)
17(1)
2.9 Iterative Partial K-Space Reconstruction
18(1)
2.10 Processing of Project
19(1)
2.11 Flow Diagram
20(9)
3 Spiral Cone-Beam CT Reconstruction
29(16)
3.1 CT Reconstruction Using the Medical Phantom Image
29(4)
3.1.1 Assessment of Image Quality of the CT Medical Phantom Image Before Reconstruction
29(3)
3.1.2 Assesment of the Image Quality of Cone-Beam Phantom After Image Reconstruction
32(1)
3.2 CT Reconstruction of the Hand Section of the Human Body
33(4)
3.2.1 Assesment of the Image Quality of CT Hand Section Before Reconstruction
34(2)
3.2.2 Assesment of the Image Quality of Cone-Beam CT Hand Section After Reconstruction
36(1)
3.3 CT Reconstruction of the Head Section of the Human Body
37(5)
3.3.1 Assesment of the Image Quality of the CT Head Section Before Reconstruction
38(3)
3.3.2 Assesment of the Image Quality of the Cone-Beam CT Head Section After Reconstruction
41(1)
3.4 Quantization of the Artifacts
42(3)
3.4.1 Assessment of Image Resolution and Noise Quantization of the Artifacts
42(3)
4 Visual Quality Improvement of CT Image Reconstruction with Quantitative Measures
45(30)
4.1 Existing System
45(1)
4.1.1 Background
45(1)
4.1.2 Criterion for Filtering Edge Information
45(1)
4.2 Proposed Algorithms
46(6)
4.2.1 Model Specification
46(2)
4.2.2 Boundary-Edge Correspondence
48(1)
4.2.3 Local Intensity Clustering Property
49(1)
4.2.4 Energy Formulation
50(1)
4.2.5 Multiphase Level Set Formulation
51(1)
4.3 Block Diagram
52(1)
4.4 Back Projection
53(1)
4.5 Filtered Back Projection (FBP) Reconstruction
54(9)
4.6 Discrete Direct Back Projection
63(1)
4.7 Data Acquisition
64(1)
4.8 Iterative Reconstruction Algorithm
65(1)
4.9 Histogram Processing
66(1)
4.10 Bias Field
67(1)
4.11 Experimental Findings
68(4)
4.11.1 Assesment of the Image Statistics of Before Image Reconstruction of CT Knee Bone
68(3)
4.11.2 Assesment of the Image Statistics of After Image Reconstruction of CT Knee Bone
71(1)
4.12 Computational Efficiency Comparison
72(3)
Bibliography 75
Vinit Kumar Gunjan is an Associate Professor at Annamacharya Institute of Technology and Sciences (AITS), India. He is the Principal Investigator for a project funded by the Science and Engineering Research Board, Department of Science & Technology, Government of India. He also serves as the Chairman of the IEEE Young Professionals and has served as the Secretary of the IEEE Computer Society, Hyderabad Chapter. He worked with Tata Consultancy Services and the School of Engineering and Technology (SET), Sharda University, Noida before joining the AITS. Vinit is a member of several IEEE Societies, the ACM, ACCS and others, and has several national and international publications to his credit.

Fahimuddin Shaik holds a PhD in Electronics and Communication Engineering and currently serves as an Associate Professor at Annamacharya Institute of Technology & Sciences (AITS) (an Autonomous Institute), India. His research interests include Signal Processing, Time Series Analysisand Biomedical Image Processing. He is the Co-Principal Investigator for a project funded by the Science Engineering Research Board, Department of Science & Technology, Government of India. He has authored the books Medical Imaging in Diabetes and Image Processing in Diabetic Related Causes and is a member of professional bodies like the IEEE, BMESI, ISTE, IACSIT, IAENG etc.

C. Venkatesh is with Annamacharya Institute of Technology & Sciences (AITS), India, where he currently serves as an Assistant Professor. He received his B.Tech in Electronics & Communication Engineering and M.Tech (Embedded Systems) from Jawaharlal Nehru Technological University. He is a member of professional bodies like the IEEE, IE, ISTE, IACSIT, IAENG etc. His research interests include Biomedical Image Processing, Embedded Systems and Signal Processing.

Amarnath M. is a Technology Consultant with Hewlett Packard Globalsoft Pvt. Ltd. Australia. He is currently on deputation with Singtel Optus Pty Ltd. He is an ITIL Foundation in IT Service Management certified practitioner focused on comprehensive IT service management and continuous service improvement. He holds a Bachelor of Technology from Sri Venkateswara University, Tirupati, India and has extensive expertise as a Software Engineer, Solution Designer, Technical Architect and Application Support Engineer.