E-raamat: Genotoxicity Assessment: Methods and Protocols

Bacterial Reverse Mutation Test - Ames Test.- The AMES II and Ames MPFTM Tests: Miniaturized Liquid Microplate Formats of the Ames Test in Petri Dishes.- In Vitro Mouse Lymphoma Cell (L5178Y Tk+/- -3.7.2.C) Forward Mutation Assay.- Erythrocyte-Based Pig-a Gene Mutation Assay.- Detection of In Vivo Mutation in the Hprt and Pig-a Genes of Rat Lymphocytes.- In Vitro Cytogenetic Assays: Chromosomal Aberrations and Micronucleus Tests.- In Vivo Micronucleus and Chromosomal Aberration Assay in Mouse Bone Marrow.- Chromosomal Aberration Test in Human Lymphocytes.- Micronucleus Assay in Human Lymphocytes and Exfoliated Buccal Cells.- 3D Liver Models for Genotoxicity Testing.- Flow Cytometric Determination of Micronucleus Frequency.- Comparative Genomic Hybridization (CGH) in Genotoxicology: From the Basics to Modern Approaches.- 32P-Postlabeling Analysis of DNA Adducts.- Multicolor Laser Scanning Confocal Immunofluorescence Microscopy of DNA Damage Response Biomarkers.- The Alkaline Comet Assay for Assessment of DNA Damage.- Application of the Comet Assay in Advanced In Vitro Models.- The Comet Assay in Human Biomonitoring.- The Comet Assay in Nano-Ecogenotoxicology.- Micronucleus Assay with Tetrad Cells of Tradescantia.- Application of Allium cepa Test for Genetic Toxicology.- Methods to Study DNA Damage Using Drosophila melanogaster.- The Wing-Spot and the Comet Tests as Useful Assays Detecting Genotoxicity in Drosophila.- Organoids for Genotoxicity Assessment.- Modern Approaches in Genetic Toxicology Research: Insights from Next-Generation-Based RNA Sequencing.- Methods to Quantify the MicroRNA and Study Their Role in Genotoxic Stress.- In Silico Approaches in Predictive Genetic Toxicology.- Artificial Intelligence and Machine Learning-Based Approaches for Genetic Damage Prediction.