Hans-Joachim Gabius (Institut fnr Physologische Chemie, Ludwig-Maximilians-UniversitSt) and Sigrun Gabius (HSmatologisch-Onkologische, Schwerpunktpraxis) present 36 chapters reviewing the chemistry and biology of carbohydrate sugars. The topics range from chemical analysis and chemical synthesis through structural determinations to the various kind of carbohydrate interactions. Biochemical topics like host defense mechanisms, signal transduction, and development and fertilization are discussed. Some of the newest materials are related to carbohydrate-recognizing molecules (lectins) in animal tissue. Annotation c. Book News, Inc., Portland, OR (booknews.com)
A comprehensive survey of the topic, ranging from basic molecular research to clinical applications. Critical reviews by leading experts in each field summarize the state of knowledge and discuss the anticipated benefits of novel approaches and strategies. These include the impact of modern analysis techniques on glycobiology, the use of synthetic neoglycoproteins, or the clinical consequences of new insights into the physiological role of lectins and glycoconjugates in pathology, oncology, immunity, neuroscience and reproduction medicine. Throughout, the aim is to separate realistic applications from mere hopes.
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