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Human Orthopaedic Biomechanics: Fundamentals, Devices and Applications [Pehme köide]

Edited by (BEAMS Department (Bio Electro and Mechanical Systems), Ecole polytechnique de Bruxelles, Universite Libre de Bruxelles, Belgium), Edited by (Head of Research Group Spine, Schulthess Clinic, Zürich, Switzerland)
  • Formaat: Paperback / softback, 758 pages, kõrgus x laius: 235x191 mm, kaal: 1560 g, Approx. 250 illustrations (250 in full color); Illustrations
  • Ilmumisaeg: 24-Feb-2022
  • Kirjastus: Academic Press Inc
  • ISBN-10: 012824481X
  • ISBN-13: 9780128244814
Teised raamatud teemal:
  • Formaat: Paperback / softback, 758 pages, kõrgus x laius: 235x191 mm, kaal: 1560 g, Approx. 250 illustrations (250 in full color); Illustrations
  • Ilmumisaeg: 24-Feb-2022
  • Kirjastus: Academic Press Inc
  • ISBN-10: 012824481X
  • ISBN-13: 9780128244814
Teised raamatud teemal:

Human Orthopaedic Biomechanics: Fundamentals, Devices and Applications covers a wide range of biomechanical topics and fields, ranging from theoretical issues, mechanobiology, design of implants, joint biomechanics, regulatory issues and practical applications. The book teaches the fundamentals of physiological loading and constraint conditions at various parts of the musculoskeletal system. It is an ideal resource for teaching and education in courses on orthopedic biomechanics, and for engineering students engaged in these courses. In addition, all bioengineers who have an interest in orthopedic biomechanics will find this title useful as a reference, particularly early career researchers and industry professionals.

Finally, any orthopedic surgeons looking to deepen their knowledge of biomechanical aspects will benefit from the accessible writing style in this title.

  • Covers theoretical aspects (mechanics, stress analysis, constitutive laws for the various musculoskeletal tissues and mechanobiology)
  • Presents components of different regulatory aspects, failure analysis, post-marketing and clinical trials
  • Includes state-of-the-art methods used in orthopedic biomechanics and in designing orthopedic implants (experimental methods, finite element and rigid-body models, gait and fluoroscopic analysis, radiological measurements)
List of contributors
xix
Preface xxiii
Acknowledgments xxv
PART 1 ORTHOPAEDIC BIOMECHANICS THEORY
Chapter 1 Introduction: from mechanics to biomechanics
3(6)
Fabio Galbusera
Bernardo Innocenti
Chapter 2 Mechanical properties of biological tissues
9(16)
Bernardo Innocenti
Introduction: material properties and structural properties
9(1)
Material properties: general concept
10(3)
Force---displacement curve and stiffness of a material
10(1)
Stress---strain curve and elastic modulus
11(1)
Normal and shear stress
12(1)
Material isotropy and anisotropy
13(1)
Stress tensor and Hooke's law
13(2)
Orthotropic, transversally isotropic, and isotropic material models
15(4)
Orthotropic material
15(1)
Transversally isotropic material
16(2)
Isotropic material
18(1)
Hyperelastic material
19(2)
Viscoelasticity and viscoelastic models
21(4)
Maxwell and Kelvin--Voight models
22(1)
Standard linear solid model
23(2)
Chapter 3 Orthopedic biomechanics: stress analysis
25(14)
Marwan El-Rich
Statics review
25(1)
Stress and strain concept
25(1)
One-dimensional simple stresses and strains
26(3)
Axial stress due to axial loading
26(1)
Sample problem
27(2)
Stresses on an oblique section under axial loading
29(1)
Normal and shear strain
30(1)
Normal stress due to pure bending (simple beam theory)
31(6)
Shear stress due to bending
32(1)
Shear strain due to torsion
33(4)
References
37(2)
Chapter 4 Orthopedic biomechanics: multibodyanalysis
39(32)
Giovanni Putame
Alessandra Aldieri
Alberto Audenino
Mara Terzini
Introduction
39(2)
Modeling strategies
41(9)
Ligaments
42(1)
Menisci
43(1)
Contacts
44(3)
Muscles
47(3)
Case studies
50(15)
Multibody model for ligament balancing in total knee arthroplasty
50(4)
Experimental kinematic data for human elbow stability estimation
54(4)
Design of experiment for prosthetic hip range of motion estimation
58(4)
Impact of the modular hip implant design on reaction forces at the neck---stem joint during walking
62(3)
References
65(6)
Chapter 5 Fundamentals of mechanobiology
71(26)
Graciosa Quelhas Teixeira
Yana Hoepfner
Cornelia Neidlinger-Wilke
Biomechanical signaling
71(3)
Mechanical stimulation and study models
74(15)
Bone
74(3)
Articular cartilage
77(3)
Intervertebral disc
80(9)
References
89(8)
Chapter 6 Bone biomechanics
97(24)
Enrico Dall'Ara
Vee San Cheong
Bone physiology
97(2)
Bone cells and (re)modeling
99(1)
Bone formation and remodeling
100(2)
Bone mechanical properties
102(6)
Bone density and structure
102(1)
Bone elasticity and anisotropy
103(3)
Bone postelastic behavior
106(2)
Bone time-dependent properties
108(1)
Assessment of bone biomechanical properties at different dimensional levels
108(6)
Ex vivo assessment of bone mechanical properties
108(1)
Organ level
108(2)
Tissue/biopsy level
110(1)
Bone structural unit/lamellar level
111(1)
In vivo assessment of bone mechanical properties
112(2)
Ageing and bone diseases
114(2)
References
116(5)
Chapter 7 Muscle biomechanics
121(16)
Dan Robbins
Introduction
121(1)
Terminology
121(1)
Anatomy
122(2)
Sliding filament theory
124(1)
Biomechanics
125(9)
Dashpot diagrams
125(2)
Length---tension curves
127(2)
Contraction types
129(2)
Fiber level modeling
131(3)
Electromyography
134(1)
References
134(1)
Further reading
135(2)
Chapter 8 Ligament and tendon biomechanics
137(14)
Fabio Galbusera
Bernardo Innocenti
Anatomy, structure, and function
137(1)
Biomechanical properties
138(4)
Experimental measurement of the biomechanical properties
142(1)
In vivo assessment of the biomechanical properties
143(1)
Entheses and aponeuroses
144(2)
Musculoskeletal maturation, aging, and exercise
146(1)
Animal models
146(1)
References
147(4)
Chapter 9 Cartilage biomechanics
151(26)
Andreas Martin Seitz
Daniela Warnecke
Lutz Durselen
Introduction
151(1)
Structural composition
152(3)
Zones
153(1)
Nutrition
154(1)
Electromechanical effects
155(1)
Biomechanics
155(15)
Viscoelasticity
157(1)
Unconfined compression and tensile testing
157(1)
Dynamic compression, creep and stress relaxation testing
158(5)
Biomechanical mapping of the joint surfaces in human knees
163(1)
Cartilage friction
164(6)
References
170(7)
Chapter 10 Meniscus biomechanics
177(22)
Andreas Martin Seitz
Maren Freutel
Lutz Durselen
Introduction
177(1)
Anatomy
177(4)
Function
181(2)
Biomechanical properties
183(1)
Tensile material properties
183(1)
Compressive material properties
184(1)
Root attachment properties
185(1)
Injury impact on meniscus performance
186(1)
Partial meniscectomy
187(1)
Total meniscectomy
187(1)
Changes in meniscus biomechanics in osteoarthritis
188(1)
Restoring the meniscus
189(1)
Sutures
189(1)
Meniscus replacement
190(3)
References
193(6)
Chapter 11 Intervertebral disc biomechanics
199(22)
Fabio Galbusera
Graciosa Quelhas Teixeira
Shape and structure
199(2)
Cartilaginous and vertebral endplates
201(1)
Osmotic swelling
202(3)
Cells and nutrition
203(2)
Biomechanical response of the discal tissues
205(2)
Biomechanics of the intervertebral disc
207(2)
Aging and degeneration
209(3)
Disc herniation
212(2)
References
214(4)
Further reading
218(3)
PART 2 HUMAN JOINTS BIOMECHANICS
Chapter 12 Biomechanics of the hip joint
221(18)
Fabio Galbusera
Bernardo Innocenti
Skeletal anatomy
221(2)
Ligaments
223(1)
Femoral axis
224(1)
Functional anatomy of the hip muscles
225(2)
Loads and stresses
227(2)
Hip cartilage and osteoarthritis
229(2)
The acetabular labrum
231(1)
Fracture of the femoral neck
232(3)
References
235(4)
Chapter 13 Biomechanics of the knee joint
239(26)
Bernardo Innocenti
Knee functional anatomy
239(8)
Knee bone
239(3)
Soft tissue envelope
242(2)
Menisci
244(1)
Muscles
244(1)
Additional soft tissues
245(2)
The tibio-femoral joint: kinematics and kinetics
247(1)
Global range of motion
247(1)
Historical knee kinematics analysis: from one degrees of freedom to six degrees of freedoms
247(2)
The Grood---Suntay coordinate system
249(2)
Medio-lateral knee kinematics model: medial pivot and roll-back knee motion
251(2)
Knee kinematics in active conditions
253(1)
Tibio-femoral kinetics
253(2)
The patello-femoral joint
255(4)
Introduction: the patellar function
255(1)
Patellar kinematics
255(1)
Muscle action
256(1)
Joint alignment
256(1)
Patellar soft tissue envelope
257(1)
Patellar contact area
257(1)
Patello-femoral forces
258(1)
References
259(6)
Chapter 14 Biomechanics of the spine
265(20)
Fabio Galbusera
Anatomy
265(4)
Flexibility and mobility
269(2)
Loads
271(1)
Degeneration
272(2)
Sagittal alignment and degenerative deformities
274(3)
Congenital, pediatric, and adolescent scoliosis
277(2)
Trauma and fractures
279(1)
References
280(5)
Chapter 15 Biomechanics of the shoulder joint
285(20)
Paolo Dalla Pria
Skeletal anatomy
285(3)
Soft tissues
288(5)
Capsule and ligaments
289(2)
Muscles
291(2)
Functional anatomy
293(5)
Stability of the glenohumeral joint
296(1)
Static stability
296(1)
Dynamic stability
296(2)
Glenohumeral forces
298(3)
Pathologies
301(1)
References
301(4)
Chapter 16 Biomechanics of the ankle joint
305(20)
Luc Labey
Preliminary definitions
305(2)
Anatomy and morphology of the human ankle joint
307(1)
Bones and joints
308(1)
The talus
309(1)
The calcaneus
310(1)
The navicular bone
311(1)
The cuboid
312(1)
Major ligaments
313(3)
Muscles and tendons
316(1)
The posterior compartment
316(1)
The anterior compartment
317(1)
The lateral compartment
318(1)
Kinematics of the human ankle joint
318(1)
The range of motion of the ankle
318(2)
Kinematics during gait
320(1)
Kinetics of the human ankle joint
321(1)
External loads on the ankle joint
322(1)
Muscle forces and joint contact forces in the ankle joint
323(1)
References
324(1)
Chapter 17 Biomechanics of wrist and elbow
325(16)
Emmannuel J. Camus
Fabian Moungondo
Luc Van Overstraeten
The wrist
325(7)
Wrist movements
326(3)
Means of carpal stability
329(1)
Carpal loads
330(2)
The elbow
332(4)
Anatomy
332(2)
Elbow stability
334(1)
Force transmission at the elbow
335(1)
Elbow motion
335(1)
References
336(5)
PART 3 BIOMECHANICS AND DESIGN OF ORTHOPAEDIC DEVICES
Chapter 18 Biomaterials and biocompatibility
341(20)
Ludovica Cacopardo
Biomaterials: definitions
341(1)
Biomaterial classes and properties
342(2)
Biomaterials for orthopedic devices
344(6)
Biotribology
350(2)
Surface functionalization
352(1)
Adding "smartness" to orthopedic implants
353(2)
Bone tissue engineering and personalized orthopedic medicine
355(1)
References
356(5)
Chapter 19 Hip prosthesis: biomechanics and design
361(16)
Edoardo Bori
Fabio Galbusera
Bernardo Innocenti
Introduction
361(1)
Implant operation
362(1)
Scores
363(1)
History of prosthesis
364(1)
Femoral component
365(2)
Acetabular component
367(1)
Fixation approaches
368(1)
Cemented
369(1)
Cementless or press-fit
369(1)
Geometry
370(2)
Hybrid fixation
372(1)
Latest designs
372(1)
Kinematics and kinetics
373(1)
References
374(2)
Further reading
376(1)
Chapter 20 Knee prosthesis: biomechanics and design
377(32)
Bernardo Innocent!
Introduction and general concepts
377(1)
Cruciate retaining and posterior stabilized implants
377(3)
Cemented and press-fit implant
380(2)
Fixed- and mobile-bearing total knee arthrdblasty
382(1)
Implant alignment and balancing
383(2)
Primary and revision total knee arthroplastys
385(1)
Total knee arthroplasty and partial knee replacement
386(1)
History of total knee prosthesis design
387(1)
Introduction
387(1)
The first hinged designs
388(1)
The first condylar implants
389(1)
Anatomical and functional approaches
389(2)
Design of a total knee replacement
391(1)
Why design a total knee arthroplasty today?
391(1)
Total knee arthroplasty design objectives, criteria, and directions
392(1)
Femoral component design
393(2)
Tibial component design
395(1)
Tibial insert design
395(2)
Patellar component design
397(1)
Additional total knee arthroplasty design aspects
397(1)
Implant size
397(1)
Design of unicompartmental knee arthroplasty
398(2)
Design of revision total knee arthroplasty: condylar constraint knee and hinged design, stem, and augment
400(2)
References
402(7)
Chapter 21 Spinal implants: biomechanics and design
409(26)
Fabio Galbusera
Instrumented spine surgery
409(1)
Pedicle screw fixation
410(3)
Interbody cages
413(2)
Cervical fixation
415(1)
Instrumentation for deformity correction
416(3)
Sacropelvic fixation
419(2)
Artificial disks
421(3)
Dynamic stabilization and other motion-preserving implants
424(1)
Fatigue failure and loosening of spinal implants
425(4)
References
429(6)
Chapter 22 Shoulder prosthesis: biomechanics and design
435(24)
Paolo Dalla Pria
Evolution of the shoulder arthroplasty
435(5)
Biomechanics of the shoulder prosthesis
440(6)
Biomechanics of the anatomical implants
440(3)
Biomechanics of the reverse implants
443(3)
Advanced design concepts of the reverse shoulder arthroplasty
446(6)
Size of the glenosphere
447(1)
Eccentricity of the glenosphere
447(1)
Glenosphere medialization/lateralization
448(1)
Neck-shaft angle
449(2)
Inlay/onlay
451(1)
Conclusion
452(1)
References
453(6)
Chapter 23 Devices for traumatology: biomechanics and design
459(26)
Pankaj Pankaj
Orthopedic trauma and its treatment
459(3)
Mechanical properties of bone
459(1)
Device materials for surgical approaches
459(1)
Treatment objectives
460(1)
Fracture healing
461(1)
Implants used for fracture fixation
461(1)
External fixators
462(5)
Pin fixators
462(3)
Ring fixators
465(2)
Internal fixation---plates and screws
467(5)
Intramedullary nailing
472(1)
Effect of healing on device choice and configuration
473(2)
Boundary conditions
475(1)
Time-dependent properties of bone
475(4)
References
479(6)
Chapter 24 Regeneration and repair of ligaments and tendons
485(16)
Rocco Aicale
Nicola Maffulli
Francesco Oliva
Introduction
485(3)
Tissue engineering for common tendon and ligament injuries
488(1)
Cells
488(1)
Scaffolds
489(1)
Growth factors
490(2)
Conclusion
492(1)
References
492(7)
Further reading
499(2)
Chapter 25 Biomechanical requirements for certification and quality in medical devices
501(14)
Silvia Pianigiani
Tomaso Villa
Certification and quality of an orthopedic medical device: requirements, regulations, laws, and procedures
501(2)
The role of the international standards in the certification process of an orthopedic medical device
503(3)
Examples on the role of standards for the demonstration of fulfillment of biomechanical requirements for an orthopedic medical device
506(1)
Fatigue performances of a hip prosthesis stem: analysis of the available standards for an experimental and computational approach
507(2)
Wear of the tibial insert of a knee prosthesis: analysis of the available standards for an experimental and computational approach
509(3)
Shoulder prosthesis: is the current standardization enough?
512(1)
Conclusion and future perspectives
513(1)
References
514(1)
Chapter 26 Clinical evaluation of orthopedic implants
515(18)
Sara Zacchetti
Overview of clinical trials of medical devices and definitions
515(4)
Clinical center
515(1)
Promoter/sponsor
516(1)
Principal investigator
516(1)
Patient/subject selection
516(1)
Pre- and postmarketing studies
516(1)
Sponsored and spontaneous studies
517(1)
Interventional and observational studies
517(1)
Retrospective, prospective, and cross-sectional studies
518(1)
Monocentric or multicenter studies
518(1)
Assignment of the procedure
518(1)
Levels of evidence
518(1)
Classification of medical devices
519(2)
Invasive and noninvasive devices
520(1)
Temporary, short-term, and long-term devices
520(1)
Active implantable devices
520(1)
Classes of risk
520(1)
In vitro medical devices
521(1)
Competent authorities and ethics committee
521(2)
Ethics committee
521(1)
National Competent Authority
522(1)
Institutional Review Board
522(1)
Other approvals and summary
522(1)
Premarket studies on medical devices
523(2)
Study design
523(1)
Budget for premarket studies
524(1)
Approval and mark
525(1)
Postmarketing studies on medical devices: interventional studies
525(2)
Study design and trial documentation
526(1)
Cost to be covered
526(1)
Submission
526(1)
Postmarketing studies on medical devices: observational studies
527(1)
Definition of observational study
527(1)
Submission package and privacy
527(1)
Costs for observational studies
528(1)
Submission
528(1)
Clinical trials on medical devices in Europe: EU regulation (745/17)
528(1)
What is new in Europe with the new regulation?
529(1)
Ethical issues related to clinical trials in orthopedics
529(1)
References
530(3)
Chapter 27 Computer-assisted orthopedic surgery
533(24)
Nicola Francesco Lopomo
Background
533(2)
Main functional components
535(1)
General workflow
536(2)
System performance
538(1)
System designs
539(6)
Passive systems
539(1)
Interactive systems
539(2)
Active systems
541(4)
Hardware architectures
545(1)
Tracking technologies
545(4)
Clinical applications
549(1)
Biomechanically enhanced surgeries
549(2)
References
551(6)
PART 4 APPLICATIONS IN ORTHOPAEDIC BIOMECHANICS
Chapter 28 Experimental orthopedic biomechanics
557(28)
Luigi La Barbera
Tomaso Villa
Bernardo Innocenti
Fabio Galbusera
Experimental tests at the organ and tissue levels
557(7)
Hard tissues
557(3)
Soft tissues
560(2)
Biphasic characterization of soft tissues
562(2)
Experimental tests on implants and prostheses
564(4)
In vitro testing
564(2)
In vivo loads on implants
566(2)
Joint simulators
568(3)
Hip
568(1)
Knee
569(1)
Spine
570(1)
References
571(14)
Chapter 29 Challenges in the system modeling of the musculoskeletal apparatus
585(24)
Serge Van Sint Jan
Victor Sholukha
State-of-the-art
585(3)
Why is detailed functional musculoskeletal system knowledge required today?
586(1)
General objectives of the research to be organized
587(1)
Methodology
588(16)
Challenge 1 Modeling of human bone variations using advanced multiple regression algorithms
588(4)
Challenge 2 Multiscale modeling on muscle architecture
592(3)
Challenge 3 Multiorgan integration and system modeling of musculoskeletal system components
595(4)
Challenge 4 Simulation of the musculoskeletal system mechanical properties and system model validation
599(5)
Conclusions
604(1)
References
605(4)
Chapter 30 Measuring joint kinematics through instrumented motion analysis
609(14)
Lennart Scheys
Introduction
609(1)
Some first basic definitions, principles, and assumptions
610(1)
The optical motion analysis system
610(2)
From tracking markers to tracking body segments
612(2)
From tracking body segments to calculating joint kinematics
614(2)
Sources of error and variability
616(2)
Conclusion
618(1)
References
619(4)
Chapter 31 Measurement of joint kinematics utilising video-fluoroscopy
623(14)
Alexander Cleveland Breen
Introduction
623(1)
History of fluoroscopy
623(1)
Equipment
624(3)
X-ray tube and generator
625(1)
Image receptors
626(1)
Safety and protection during a fluoroscopic acquisition
627(1)
Why use fluoroscopy for mechanical measurements?
628(1)
Skin surface measurements
628(1)
2D tracking
629(1)
Manual versus automated tracking
629(1)
2D-3D registration
629(2)
Clinical biomechanics utility/joint motion
631(1)
The future
632(1)
References
633(2)
Further reading
635(2)
Chapter 32 Finite element analysis in orthopedic biomechanics
637(22)
Markus O. Heller
Finite element analysis as a method
637(1)
General considerations for conducting FEA
637(2)
Mesh convergence analysis and model validation
638(1)
A case study
639(12)
Mesh generation
639(1)
Material properties
640(1)
Boundary conditions
641(2)
Loading conditions
643(2)
Mesh convergence analysis
645(2)
Case study data analysis
647(4)
Model validation
651(2)
Summary and conclusion
653(1)
References
653(6)
Chapter 33 Rigid-body and musculoskeletal models
659(22)
Michael Skipper Andersen
Introduction
659(1)
Fundaments of rigid-body and musculoskeletal modeling
659(4)
Musculoskeletal modeling
663(3)
Human---bicycle model
663(1)
2D lower extremity model
664(1)
Bicycle model
665(1)
Human---bicycle interaction model
666(11)
Kinematic analysis
667(2)
Inverse dynamic analysis
669(2)
Analysis of human---bicycle dynamics
671(3)
Other applications
674(3)
Concluding remarks
677(1)
References
678(3)
Chapter 34 The use of computational models in orthopedic biomechanical research
681(32)
Bernardo Innocenti
Edoardo Bori
Federica Armaroli
Benedikt Schlager
Rene Jonas
Hans-Joachim Wilke
Fabio Galbusera
Introduction
681(1)
The hip joint
682(2)
The healthy and degenerated hip joint
683(1)
The implanted hip joint
684(1)
The knee joint
684(3)
The healthy and degenerative knee joint
685(2)
The implanted knee joint
687(1)
The spine
687(5)
The healthy and degenerated spine
688(2)
The implanted spine
690(2)
The shoulder joint
692(2)
The healthy and degenerated shoulder joint
692(1)
Shoulder joint replacement
693(1)
The ankle joint
694(4)
The healthy and degenerated ankle joint
695(1)
Ankle joint replacement
696(2)
Verification, validation, and calibration of orthopedic computational models
698(2)
Limitations
700(1)
Future developments
700(1)
Conclusions
701(1)
References
702(11)
Index 713
Prof. Bernardo Innocenti has been working in the field of knee orthopaedic biomechanics from more than 17 years. During his entire career he has been involved in several research projects that, applying experimental and computational methodologies, alone or together, investigate the kinematics and the kinetics of the human knee joint, in healthy or pathologic conditions and, also, with a prosthesis. He is author of co-author of more than 100 peer-reviewed publications about knee biomechanics. The analysis of the musculoskeletal loading in healthy and pathological subjects, the stress distribution in bone and in implant, and the study of prosthesis design, together with the simulation of bone remodeling and implant wear, are also additional fields in which he has been involved. Fabio Galbusera, engineer, is the Head of Spine Research at the Schulthess Clinic in Zürich, Switzerland. His main research interests are the biomechanics of the spine, the use of numerical models for its investigation as well as spinal imaging, about which he published more than 170 papers in international peer-reviewed journals. In the last years, he pioneered the use of artificial intelligence in the field of spine research, especially for the automated analysis of radiological images of the spine. One of his works in this field was awarded the ISSLS Prize for Bioengineering 2021. He is a member of the International Society for the Study of the Lumbar Spine (ISSLS), the Spine Society of Europe (EUROSPINE), the European Society of Biomechanics (ESB) and the European Society of Radiology (ESR), and is currently part of the Editorial Boards of Journal of Biomechanics, European Spine Journal, Frontiers in Bioengineering and Biotechnology and of European Radiology Experimental.Regarding books, in 2018 he edited the book Biomechanics of the Spine: Basic Concepts, Spinal Disorders and Treatments” together with Prof. Hans-Joachim Wilke, published by Elsevier.