Common Acronyms And Abbreviations |
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xxi | |
Summary |
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1 | (14) |
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15 | (16) |
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1.1 Low-Dose Radiation Exposures to the U.S. Population |
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19 | (3) |
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1.2 Low-Dose Radiation Research in the United States |
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22 | (6) |
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1.3 Study Task and Approach |
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28 | (2) |
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30 | (1) |
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2 Low-Dose Radiation Exposures And Health Effects |
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31 | (44) |
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2.1 Low-Dose Radiation Sources and Exposures |
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33 | (31) |
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38 | (5) |
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43 | (4) |
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2.1.3 Occupational Exposures |
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47 | (2) |
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2.1.4 Nuclear Power Operations |
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49 | (4) |
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2.1.5 Nuclear or Radiological Incidents |
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53 | (3) |
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2.1.6 Nuclear Weapons Program |
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56 | (5) |
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2.1.7 Nuclear Waste Management |
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61 | (3) |
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2.2 Current Epidemiological Evidence on Low-Dose Radiation Health Effects |
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64 | (9) |
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64 | (2) |
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2.2.2 Cardiovascular Disease |
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66 | (1) |
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2.2.3 Neurological Disorders |
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67 | (1) |
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68 | (2) |
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70 | (1) |
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2.2.6 Heritable Genetic Effects |
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71 | (2) |
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2.3 Chapter Summary and Finding |
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73 | (2) |
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3 Scientific Basis For Radiation Protection |
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75 | (22) |
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3.1 The Radiation Protection Framework |
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75 | (5) |
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3.2 Agencies with Radiation Protection Responsibilities in the United States |
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80 | (2) |
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3.3 Science Behind Radiation Protection |
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82 | (11) |
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3.3.1 The Regulatory Development Process |
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84 | (1) |
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3.3.2 Decision-Making Frameworks for Radiation Protection |
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85 | (1) |
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3.3.3 Characterization of Risk in the Regulatory Development Process |
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86 | (7) |
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3.4 Potential Economic Impacts of the Low-Dose Radiation Research Program |
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93 | (2) |
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3.5 Chapter Summary and Findings |
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95 | (2) |
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4 Status Of Low-Dose Radiation Research |
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97 | (30) |
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4.1 Low-Dose Radiation Research in the U.S. Government |
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97 | (13) |
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4.1.1 Department of Energy |
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98 | (3) |
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4.1.2 National Aeronautics and Space Administration |
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101 | (3) |
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4.1.3 National Institutes of Health |
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104 | (2) |
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4.1.4 Centers for Disease Control and Prevention |
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106 | (2) |
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4.1.5 Department of Defense |
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108 | (1) |
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4.1.6 National Science and Technology Council |
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109 | (1) |
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4.1.7 Intelligence Advanced Research Projects Activity |
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110 | (1) |
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4.2 Low-Dose Radiation Research in National Laboratories |
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110 | (3) |
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4.3 Low-Dose Radiation Research in Universities |
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113 | (1) |
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4.4 Support for Low-Dose Radiation Research by Other U.S. Entities |
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113 | (2) |
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4.4.1 National Council on Radiation Protection and Measurements |
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113 | (1) |
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4.4.2 Electric Power Research Institute |
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114 | (1) |
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4.4.3 Health Physics Society |
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114 | (1) |
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4.4.4 American Nuclear Society |
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115 | (1) |
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4.5 Support for Low-Dose Radiation Research Internationally |
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115 | (11) |
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4.5.1 Multidisciplinary European Low-Dose Initiative |
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116 | (1) |
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4.5.2 International Commission on Radiological Protection |
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117 | (1) |
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4.5.3 United Nations Scientific Committee on the Effects of Atomic Radiation |
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117 | (2) |
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4.5.4 Nuclear Energy Agency/Organisation for Economic Co-operation and Development |
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119 | (1) |
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4.5.5 Support for Low-Dose Radiation Research in Canada |
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120 | (2) |
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4.5.6 Support for Low-Dose Radiation Research in Japan |
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122 | (4) |
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126 | (1) |
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5 Prioritized Research Agenda |
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127 | (62) |
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5.1 Low-Dose Radiation Research Challenges and Overview of Research Priorities |
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127 | (7) |
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5.2 Epidemiological Research Priorities |
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134 | (12) |
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5.2.1 Develop and Deploy Analytical Tools for Radiation Epidemiology (Priority El) |
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134 | (5) |
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5.2.2 Improve Estimation of Risks for Cancer and Non-Cancer Health Outcomes from Low-Dose External and Internal Radiation Exposures, Including Suitable Surrogate Biomarkers of Health Risk Where Appropriate (Priority E2) |
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139 | (3) |
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5.2.3 Determine Factors That Alter the Low-Dose and Low-Dose-Rate Radiation-Related Adverse Health Effects (Priority E3) |
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142 | (4) |
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5.3 Biological Research Priorities |
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146 | (14) |
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5.3.1 Develop More Accurate Model Systems for Study of Low-Dose and Low-Dose-Rate Radiation-Induced Health Effects (Priority B1) |
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146 | (5) |
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5.3.2 Develop Biomarkers for Radiation-Induced Adverse Health Outcomes (Priority B2) |
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151 | (3) |
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5.3.3 Define Health-Effect Dose-Response Relationships Around 10 mGy or 5 mGy/h (Priority B3) |
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154 | (3) |
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5.3.4 Identify Factors That Modify or Confound Estimation of Risks for Radiation-Induced Adverse Health Outcomes (Priority B4) |
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157 | (3) |
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5.4 Research Infrastructure Priorities |
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160 | (20) |
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5.4.1 Tools for Sensitive Detection and Precise Characterization of Aberrant Cell and Tissue States (Priority II) |
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160 | (8) |
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5.4.2 Harmonized Databases to Support Biological and Epidemiological Studies (Priority 12) |
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168 | (2) |
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5.4.3 Dosimetry for Low-Dose and Low-Dose-Rate Exposures (Priority 13) |
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170 | (4) |
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5.4.4 Facilities for Low-Dose and Low-Dose-Rate Exposures (Priority 14) |
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174 | (6) |
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5.5 Estimated Timeline and Costs |
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180 | (4) |
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5.6 Comparison of the Committee-Recommended Research Agenda to Those of Other Entities |
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184 | (1) |
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5.7 Chapter Summary, Findings, and Recommendation |
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185 | (4) |
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6 Essential Components Of The Low-Dose Radiation Program |
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189 | (78) |
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6.1 Programmatic Commitment |
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190 | (1) |
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6.2 Independent Advice and Evaluation |
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191 | (4) |
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195 | (1) |
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6.4 A Prioritized Strategic Research Agenda |
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196 | (1) |
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6.5 Research-Sponsorship Mechanisms |
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196 | (5) |
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6.5.1 Development of Research Solicitation |
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197 | (1) |
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6.5.2 Review of Applications |
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197 | (1) |
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197 | (2) |
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199 | (1) |
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6.5.5 Data Management and Sharing |
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199 | (1) |
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6.5.6 Dissemination of Scientific Results |
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200 | (1) |
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201 | (3) |
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6.7 Engagement and Communications with Stakeholders |
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204 | (5) |
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209 | (5) |
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6.8.1 Mechanisms for Coordination |
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209 | (3) |
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212 | (2) |
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6.9 Department of Energy and Management of the Low-Dose Program |
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214 | (3) |
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215 | (1) |
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215 | (1) |
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6.9.3 Views of Members of the Scientific Community |
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216 | (1) |
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6.9.4 Views of Members of the Impacted Communities |
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216 | (1) |
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6.9.5 The Committee's Views |
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216 | (1) |
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6.10 Chapter Summary, Findings, and Recommendation |
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217 | (4) |
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221 | (46) |
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A Consolidated Appropriations Act, 2021 |
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267 | (4) |
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B Committee and Staff Biographies |
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271 | (10) |
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C Information-Gathering Meetings |
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281 | (8) |
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D Projects Designated by the Department of Energy as "Low-Dose Radiation Projects" Carried Out at National Laboratories (2016-2021) |
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289 | (6) |
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E Unedited Responses from Radiation Facilities |
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295 | |