This book provides insights into current developments and the revolution in industrial applications of miniaturized bioreactors. Miniaturized bioreactors transform industrial biotechnology by facilitating quick, efficient, and cost-effective development. These small-scale bioreactors enable high-throughput screening of many conditions simultaneously, speeding up the tuning of critical parameters such as temperature, pH, and nutrition delivery. This results in higher product yields, better quality, and faster bioprocess scale-up. Miniaturization also saves vital resources and lessens the environmental impact of bioproduction. By providing a diverse platform for bioprocess development, miniaturized bioreactors can potentially accelerate biotechnology innovation and sustainability. The book further discusses the role of miniature bioreactors in microbial screening, high-throughput cellular screening, the revolutionizing of upstream and downstream processing systems along with numerous potential applications. The subsequent sections describe the uses of miniaturized bioreactors across industrial biotechnology, including biopharmaceuticals, drug development, small- and large-scale industries, and the food and beverage sectors.
1. Miniaturized Bioreactors: Advancement in Microalgae Screening
Process.-
2. Miniatured Bioreactor in Microalgae Research for Sustainable
Bioprocessing.-
3. Miniaturized Bioreactors: Transforming Upstream Processing
in Biopharmaceuticals.-
4. Transforming screening of bacterial cell cultures
using miniaturized bioreactors for industrial biotechnology processes.-
5.
Targeting the Gut with Precision: Microbioreactors in Next-Gen Probiotic
Screening.-
6. Miniaturized Bioreactors in Animal Cell Culture - A Paradigm
Shift in Bioprocess Industry for High Throughput Screening.-
7. The Next
Frontier in Bioprocess Engineering: Miniaturized Bioreactors and Their
Multisectoral Applications.-
8. Miniaturized Bioreactors in the Food &
Beverage Industries.-
9. Miniaturized Bioreactors: A New Era Revolutionizing
Recombinant Protein Production.-
10. Advances in miniaturized bioreactors for
scalable recombinant protein bioprocessing.-
11. Innovations in Miniaturized
Bioreactors for commercial applications.-
12. Miniaturized Bioreactors:
Bridging the Gap between Small-Scale and Large-Scale Production Lines.-
13.
The Advancement of Organoid-Based Miniaturized Bioreactors in Drug
Development and Drug Screening.
Dr. Saroj Kumar is an Associate Professor and Coordinator of the School of Biosciences at Apeejay Stya University, Gurugram, India. He earned his M.Sc. in Biotechnology from Bundelkhand University, Jhansi, India. He has completed his Ph.D. in Biotechnology from CSIR-Institute of Genomics and Integrative Biology and Department of Biotechnology, Bundelkhand University, Jhansi, India. Dr. Kumar has over 13 years of post-Ph.D. research and teaching experiences at prestigious national and international institutions, including a postdoctoral position at Linnaeus University in Sweden. Dr. Kumar's teaching and research interests span a variety of fields, including biosensors, cytoskeleton proteins, diagnostic devices, nanobiotechnology, bioconjugation techniques, bioreactors, and enzyme technology. His research primarily focuses on developing miniaturized platforms for biosensing devices, as well as bioreactor and flow-through reactor systems. Dr. Kumar specializes in engineering miniaturized processes, actin protein engineering, biosensors, bioconjugation, and bioremediation technologies. He has successfully completed research funded by external grants and has published over 30 peer-reviewed articles and book chapters. Additionally, Dr. Kumar has presented his work at numerous national and international conferences, including both oral and poster presentations. He has reviewed numerous articles for peer-reviewed journals.
Dr. Lakhan Kumar works as an Assistant Professor of Biological Sciences & Engineering at Maulana Azad National Institute of Technology, Bhopal, India. He completed his B.Tech. in Biotechnology from the National Institute of Technology, Jalandhar (An Institute of National Importance, Government of India). He obtained his M.Tech. in Industrial Biotechnology and Ph.D. in Algal Biotechnology from Delhi Technological University, Delhi (A Public University, Government of NCT Delhi, India), where he investigated the application of microalgae for biodiesel production, accumulation, and enhancement of biochemicals of industrial significance, synthesis of biochar and nanoparticles for environmental remediation. He has more than eight years of academic and research experience. He has been awarded the Research Excellence Award from Delhi Technological University, Delhi. He has published over 50 peer-reviewed articles, including seven books on biofuels, biorefinery, and bioremediation. He actively participates in Training, Conferences, Workshops, and Seminars on recent trends in Bio-based resource recovery, bioprocessing, bioremediation, nanobiotechnology, and biofuels
