Neurocritical care is a multidisciplinary specialty that provides comprehensive management for all life-threatening disorders of the central nervous system and their complications. Increased understanding of the pathophysiology of acute central nervous system disorders and their impact on systemic organ systems, in association with advances in neuromonitoring and neuroimaging techniques, has led to the introduction of more effective and individualised treatment strategies that have translated into improved outcomes for critically ill neurological patients. As well as treatments targeted to the acute neurological disorder, critically ill neurological patients require meticulous general intensive care support to maintain systemic physiological stability and optimize neurological outcomes.
The second edition of the Oxford Textbook of Neurocritical Care brings together international experts from various disciplines to provide a comprehensive global perspective on this field. In 33 updated or new chapters, the book discusses the pathophysiology of acute neurological conditions, advancements in monitoring and imaging techniques, evidenced-based treatment strategies, prognostication, patient outcomes, and ethics. Each chapter highlights advancements within specific areas and underscores the critical attention to detail that is the basis of neurocritical care practice.
While primarily designed for those in the neurocritical care field, this textbook also serves as a valuable resource for other clinical professionals who encounter patients with acute neurological conditions in their practice. It is also a useful resource for trainees from many disciplines
1: Kelley Flesher, W. Andrew Kofke, and Ramani Balu: Applied
Neurophysiology & Neuropharmacology 2: Ossama Khazzaal, and W. Andrew Kofke:
Physiology of Cerebral Blood Flow 3: Michele Salvagno, Chiara Robba, and
Fabio Silvio Taccone: Cardiorespiratory Support 4: Abdullah Bib Zahid, and
Jose Suarez: Fluid Management 5: Patrick Mark Wanner, Geert Meyfroidt, and
Luzius A. Steiner: Sedation & Analgesia 6: Yaseen M. Arabi, and Jean-Charles
Preiser: Nutrition 7: Carolina Iaquaniello, and Giuseppe Citerio:
Intracranial Pressure 8: Nuno V. Gomes, and Luzius A. Steiner: Cerebral Blood
Flow Monitoring 9: Matthew R. Leach, and Lori A. Shutter: Monitoring Cerebral
Oxygenation 10: Sara Venturini, Keri L.H Carpenter, Peter J. Hutchinson, and
Adel Helmy: Cerebral Microdialysis 11: J. Claude Hemphill, and Rajat Dhar:
Multiomodal Monitoring & Artificial Intelligence 12: Aarti Sarwal, Chiara
Robba, and Giuseppe Citerio: Brain Echography 13: Elizabeth E. Carroll, and
Jan Claassen: Electrophysiology 14: Sara Shams, Mana Shams, and Max
Wintermark: Neuroimaging 15: Nicolas Bruder: Postoperative Care 16: Tommi K.
Korhonen, Angelos Kolias, Richard T. Protheroe, and Peter J. Hutchinson:
Traumatic Brain Injury 17: Katharina Busl, Sema Akkus, and Carolina Maciel:
Subarachnoid Haemmorhage 18: Craig S. Anderson and Magdy H. Selim:
Intracerebral Haemorrhage 19: Ugan Reddy and Martin Smith: Acute Ischaemic
Stroke 20: Anahita Malvea, Laureen D. Hachem, and Michael G. Fehlings: Spinal
Cord Injury 21: Maxwell S. Damian and Werner J. Z 'Graggen: Neuromuscular
Disorders 22: Jan Novy, and Andrea O. Rossetti: Epilepsy & Status Epilepticus
23: Pedro Kurtz, and Romain Sonneville: Infection & Inflammation 24: Virginia
F.J. Newcombe, and Elisa R. Zanier: Neuro-COVID 25: Jerry P. Nolan, and
Claudio Sandroni: Postcardiac Arrest Syndrome 26: Leandro R.D Sanz, Oliver
Bodart, and Steven Laureys: Disorders of Consciousness 27: Ian C.
Schoonbaert, and Andreas H. Kramer: Nonneurological Complications 28: Mathieu
Van der Jagt, and Marcel Aries: Electrolyte & Endocrine Disturbances 29: Emma
Harley, Valerie Rae and Tsz-Yan Milly Lo: Paediatric Neurocritical Care 30:
Gentle Sunder Shrestha, Ritesh Lamsal, and Indranil Ghosh: Neurocritical Care
in Resource Poor Environments 31: Ariane Lewis, and Rafael Badenes: Brain
Death 32: Michael J. Souter, and Jan Gunst: Organ Donation 33: Erwin J.O
Kompanje: Ethics
Martin Smith MBBS, FRCA, FFICM is honorary professor at University College London and emeritus consultant in neuroanesthesia and neurocritical care at University College London Hospitals. He is editor-in-chief of the Journal of Neurosurgical Anesthesiology. Martin Smith is Past President of the Society for Neuroscience in Anesthesiology and Critical Care and Past President of the Neuroanaesthesia and Critical Care Society of Great Britain & Ireland. His research interests include monitoring and managing the injured brain. Dr Smith has published extensively on topics related to neurocritical care and brain injury -
Giuseppe Citerio, MD, is professor of Anesthesia and Intensive Care at the Milano Bicocca University, School of Medicine and Surgery. He is Director of the Neuroscience Department and Director of Anesthesia and Neurosurgical Intensive Care at IRCCS San Gerardo Hospital, Monza. Guiseppe is an Editor-in-Chief of Intensive Care Medicine since 2019 , he has published over 550 indexed articles and his research activities focused on traumatic brain injury, subarachnoid hemorrhage, coma, neuroanesthesia, neurointensive care, and brain death/organ donation.
W Andrew Kofke completed his anesthesiology residency and critical care fellowship training at Mass General, USA. He had faculty positions at Hershey Medical Center (83-88), University of Pittsburgh (88-96), West Virginia University (96-00), and UPenn (00-24). He is director of neuroanesthesia at all three institutions and initiated the founding of a neuro ICU at the University of Pittsburgh and the neurocritical program at UPenn. He has published research related to brain energy metabolism, CBF assessment and monitoring, multimodality neuromonitoring, and opioid neurotoxicity.
Geert Meyfroidt MD, PhD is professor of medicine at the University of Leuven and Consultant Intensivist at the University Hospitals Leuven, in Belgium. He is funded by the Flemish Government as a Senior Clinical Investigator. Current research projects include data mining and predictive modelling in neuro-intensive care and acute kidney injury; clinical and laboratory studies on cerebrovascular autoregulation, and; ketamine and brain injury. Dr Meyfroidt is past-president of the Belgian Society of Intensive Care Medicine, past-chair of the Neuro-Intensive Care section of the European Society of Intensive Care Medicine, and Section Editor of Intensive Care Medicine.
