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E-raamat: Perspectives on Research with H5N1 Avian Influenza: Scientific Inquiry, Communication, Controversy: Summary of a Workshop

  • Formaat: 132 pages
  • Ilmumisaeg: 04-Apr-2013
  • Kirjastus: National Academies Press
  • Keel: eng
  • ISBN-13: 9780309267762
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  • Formaat: 132 pages
  • Ilmumisaeg: 04-Apr-2013
  • Kirjastus: National Academies Press
  • Keel: eng
  • ISBN-13: 9780309267762

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When, in late 2011, it became public knowledge that two research groups had submitted for publication manuscripts that reported on their work on mammalian transmissibility of a lethal H5N1 avian influenza strain, the information caused an international debate about the appropriateness and communication of the researchers' work, the risks associated with the work, partial or complete censorship of scientific publications, and dual-use research of concern in general.



Recognizing that the H5N1 research is only the most recent scientific activity subject to widespread attention due to safety and security concerns, on May 1, 2012, the National Research Council's Committee on Science, Technology and Law, in conjunction with the Board on Life Sciences and the Institute of Medicine's Forum on Microbial Threats, convened a one-day public workshop for the purposes of 1) discussing the H5N1 controversy; 2) considering responses by the National Institute of Allergy and Infectious Diseases (NIAID), which had funded this research, the World Health Organization, the U.S. National Science Advisory Board for Biosecurity (NSABB), scientific publishers, and members of the international research community; and 3) providing a forum wherein the concerns and interests of the broader community of stakeholders, including policy makers, biosafety and biosecurity experts, non-governmental organizations, international organizations, and the general public might be articulated.



Perspectives on Research with H5N1 Avian Influenza: Scientific Enquiry, Communication, Controversy summarizes the proceedings of the workshop.

Table of Contents



Front Matter 1 Introduction 2 The Quickening Pace of Biological Research and Current Challenges in Biosecurity 3 Influenza 4 Scientists and the Social Contract 5 Governance and Oversight 6 Moving Forward Appendixes Appendix A: Timeline Appendix B: Official Statements Appendix C: The Two Published H5N1 Papers Appendix D: Workshop Agenda Appendix E: Workshop Attendees Appendix F: Biographical Information of Committee and Staff
1 Introduction
1(4)
The H5N1 Controversy
1(2)
Dual-use Research
3(2)
2 The Quickening Pace Of Biological Research And Current Challenges In Biosecurity
5(10)
Developments in Microbiology
5(4)
Developments at the Intersection of Biosecurity and Science
9(6)
3 Influenza
15(14)
Virulence, Transmissibility, and the Importance of Mutations for Influenza A Viruses
15(4)
Case Studies: The 1918 Spanish Influenza Pandemic and H5N1
19(10)
4 Scientists And The Social Contract
29(6)
Transparency, Public Participation and Confidence, and the Media
33(1)
The Role of Corporations in Life Sciences Research
34(1)
5 Governance And Oversight
35(10)
U.S. Policy on Dual-use Research of Concern
36(1)
Role of Research Institutions
37(1)
Implications for International Policies
38(7)
6 Moving Forward
45(6)
Regulatory Paths, Gray Zones, and Avoiding Undue Burdens
45(1)
Dual-use Research: What's In a Name?
46(1)
Risk
47(1)
Broad and Inclusive Participation
47(1)
The Need to Revamp the Education of our Next Generation of Scientists
48(3)
Appendixes
A Timeline
51(4)
B Official Statements
55(26)
C The Two Published H5N1 Papers
81(20)
D Workshop Agenda
101(2)
E Workshop Attendees
103(4)
F Biographical Information of Committee and Staff
107