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E-raamat: Quantum Mechanics, Cell-Cell Signaling, and Evolution

(Professor of Pediatrics, Obstetrics and Gynecology, and Evolutionary Medicine, University of California- Los Angeles, USA)
  • Formaat: PDF+DRM
  • Ilmumisaeg: 09-Sep-2022
  • Kirjastus: Academic Press Inc
  • Keel: eng
  • ISBN-13: 9780323972819
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Quantum Mechanics, Cell-Cell Signaling, and EvolutionSuurem pilt
  • Formaat: PDF+DRM
  • Ilmumisaeg: 09-Sep-2022
  • Kirjastus: Academic Press Inc
  • Keel: eng
  • ISBN-13: 9780323972819
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Quantum Mechanics, Cell-Cell Signaling, and Evolution offers a detailed accounting of the latest research and theorizing on the integration of quantum physics with biological action to produce a novel perspective on evolution. The book advocates for a paradigm shift towards understanding biology and medicine causally as predictive sciences, presenting quantum mechanics and physiology as vertically integrated. The author has taken a unique approach to the question of how and why evolution occurred. The account is based on extensive knowledge of lipid physical chemistry, and its role in the evolution of the lung under the influence of hormonal effects on structure and function.

The title arranges lipid biochemistry and biophysics into an integrated explanation, guiding readers from the immersion of lipids in water as the origin of life, to lung surfactant in alveolar homeostasis, and leading to a new understanding of how consciousness interacts with the laws of nature. This volume argues for a novel understanding of evolutionary processes based on fundamental science and positions itself as seeking consilience among research disciplines. Starting from the origins of the cosmos, the author proceeds through nucleosynthesis and Endosymbiosis Theory, to finally describe consciousness in relation to natural law.

  • Offers a novel account of evolutionary mechanisms integrating quantum mechanics and cell-cell signaling
  • Presents the latest research and theorizing on the integration of quantum physics with biological action
  • Grounds theoretical insights in lipid physical chemistry and the evolution of the lung
  • Details an integrated, causal account of evolution operating across physical and biological domains
  • Argues for a paradigm shift in the way evolution is understood
Preface xi
Acknowledgments xiii
1 The cell membrane as a functional Mobius strip
1(10)
Introduction
1(1)
The cell membrane as the prototype for the Mobius strip
2(1)
Micelles, semipermeable membranes, and calcium ion fluxes
3(1)
Calcium ions passing through the cell constitute the biologic flow of energy
3(1)
The evolution of multicellularity
4(2)
Epigenetic inheritance
6(1)
Conclusions
7(1)
References
8(1)
Further reading
9(2)
2 Consciousness, the "missing link" between physics and physiology
11(6)
3 The unicell as the crucible for consciousness as Quantum Entanglement
17(10)
Introduction
17(1)
"Life is that Which Can Mix Oil and Water"---Robert Frost
18(2)
The vector formed by the Big Bang
20(1)
Observer-observed?
21(1)
Entanglement forms "knots"
22(1)
Cryptochrome, FAD, and magnetoreception
22(1)
Skepticism about Quantum Biology due to decoherence
23(1)
Discussion
23(3)
References
26(1)
4 Cybernetics as a conversation with the Cosmos
27(14)
Prelude
27(1)
Introduction
27(2)
The origin of life as our Cybernetic "dialog" with the Cosmos
29(4)
Big Bang
33(1)
Physiology as Ross Ashby's Black Box of Cybernetics
33(1)
(Non)conscious or (sub)conscious Cybernetics
34(1)
On the Cybernetics of auto-engineering
35(2)
Discussion
37(1)
Acknowledgment
38(1)
References
39(1)
Further reading
40(1)
5 Disambiguation, evolution, and the topology of consciousness
41(10)
Introduction
41(1)
The homology between evolution and knots
42(2)
Circles, knots, cells, and memory
44(1)
DNA knots, Homeobox genes, and cell-cell signaling
45(1)
Preadaptations, lipids immersed in water, and knots
45(2)
The deep significance of the homology between knots and evolution
47(1)
The metaphysics of knots
47(1)
Left-right brain as the resolution of Quantum Mechanics in biology: A hypothesis
48(1)
Discussion
49(1)
Reference
50(1)
6 On the evolution of evolution
51(6)
7 The continuum from physics to cosmology
57(18)
Introduction
57(2)
The Big Bang of the Singularity gave rise to both the physical and biologic realms
59(1)
A feasible pathway for quantum evolutionary development through cell-cell interactions
59(1)
Mayr's proximate and ultimate causes of evolution
60(2)
Comparing apples with apples
62(1)
Epigenetic inheritance infers the primacy of the unicellular state
63(1)
Pauli Exclusion Principle: Homolog for the First Principles of Physiology
64(1)
Nonlocality in physics and biology
65(2)
Coherence as Schrodinger wave collapse
67(1)
Heisenberg Uncertainty Principle facilitates biologic ambiguity
68(1)
Physiology as recursive fractals
69(3)
The narrative version of vertebrate evolution
72(1)
Consciousness as the aggregate of the inanimate to the animate
73(1)
Conclusions
73(1)
References
74(1)
8 Quantum Mechanics predicts evolution
75(12)
Introduction
75(2)
Quantum Mechanics and origins and causation in biologic evolution
77(2)
The predictive value of a Quantum Mechanical approach to evolution
79(1)
The unicell-multicell approach predicts the iterative evolution of niche construction: A holistic approach
80(1)
The forward-directed continuum of evolution predicts the foundational role of Quantum Mechanics
81(1)
Physiology as a homolog for quantum coherence?
81(1)
The cytoskeleton as the homolog for self-organization and consciousness
81(2)
Discussion
83(1)
References
84(3)
9 Goldilocks effect as local paracrine control of homeostasis and endocrinology
87(12)
Introduction
87(1)
Micro- to macroevolution
87(3)
The phylogenetic history of the thyroid
90(2)
An evolutionary vertical integration of the phylogeny and ontogeny of the thyroid
92(2)
Wolff's Law and bone remodeling
94(1)
Goodpasture's syndrome
94(1)
Salinity and the vitamin D receptor
95(2)
References
97(2)
10 The atom and cell are homologous point sources in a quantum world
99(20)
Introduction
99(2)
Biology and physics
101(6)
On the origin of complex physiology
107(3)
The evolution of visceral organs
110(1)
Mechano-transduction and evolutionary fundaments
111(4)
Biologic time as artifact
115(1)
In conclusion---The cell as the first niche construction
116(2)
References
118(1)
11 The Vitruvian Cell
119(6)
Introduction
119(1)
Da Vinci's Vitruvian Man
119(2)
Math, geometry, biology, and metaphysics
121(1)
Leonardo da Vinci
122(1)
Homology between the cell and a crossword puzzle
122(3)
12 Implicate and Explicate Orders as unconscious and conscious
125(24)
Introduction
125(2)
The Periodic Table of Elements and You
127(4)
The environment gave rise to endothermy
131(3)
The Periodic Table and Evolutionary Biology are diachronic vectors of the Big Bang
134(3)
Information Theory meets Informatics
137(1)
Truth be told
138(1)
There is only space, there is no time
139(1)
A novel prediction of Consciousness as the Singularity
140(1)
The vertical integration of gravity, chemistry, and biology as Consciousness
141(2)
Biology and chemistry as vectoral fractals of the Big Bang
143(1)
Terminal Addition and Phantom Limb as "Proof of Principle" for Physiology as our Implicate Order
144(1)
Conclusions
144(1)
References
145(4)
13 The latticework of both the Cosmos and physiology
149(8)
Introduction
149(1)
Nucleosynthesis---First 36 Elements, all relevant to physiology with the exception of iodine, 53, which became adapted by the thyroid
149(2)
Evolutionary vertical integration of the phytogeny and ontogeny of the thyroid
151(1)
Symbiogenesis, Terminal Addition, and cell-cell signaling
152(1)
Gravity is necessary for life and forms the basis for the lattice
153(1)
Synchronicity as a product of latticework
153(1)
Phantom Limb, Terminal Addition, and latticework
153(1)
Quantum Mechanics and latticework: Quantum Chromodynamics theory
154(1)
Using the "reverse-evolution" approach to emergence led from Symbiogenesis to Quantum Entanglement/nonlocalization: But where did QM evolve from? Particle Physics, including QCD theory as the common lattice work of the Cosmos
154(1)
References
155(2)
Afterword 157(2)
Author Index 159(2)
Subject Index 161
John S. Torday is Professor of Pediatrics, Obstetrics and Gynecology, and Evolutionary Medicine, at the University of California- Los Angeles, USA. He has published over 200 papers on lung biology, and over the course of the last 20 years, more than 100 peer-reviewed articles regarding the evolution of physiology based on cellular-molecular principles of development and phylogeny, by exploiting cell-cell signalling as the underlying mechanism. In addition, he has authored or co-authored six books on this topic that are unique to the literature on biology, medicine, cell biology, developmental biology and pathophysiology. He has taken a unique approach to the question of how and why evolution has occurred based on extensive knowledge of lipid physical chemistry, having studied its role in lung evolution under the influence of hormonal effects on structure and function developmentally, physiologically and pathologically.
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