| Preface |
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| Contributors |
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Part I Challenges in Veterinary Vaccine Development |
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1 Challenges in Veterinary Vaccine Development and Immunization |
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3 | (36) |
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Part II Vaccines for Farm Animals |
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2 Development of Mycoplasma hyopneumoniae Recombinant Vaccines |
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39 | (12) |
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Silvana Beutinger Marchioro |
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3 Computational Prediction of Immunodominant Epitopes on Outer Membrane Protein (Omp) H of Pasteurella multocida Toward Designing of a Peptide Vaccine |
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51 | (8) |
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4 DNA Vaccines Against Maedi--Visna Virus |
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59 | (18) |
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5 Detection of Avian Antigen-Specific T Cells Induced by Viral Vaccines |
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77 | (12) |
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Helle Risdahl Juul-Madsen |
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6 Generation of Newcastle Disease Virus (NDV) Recombinants Expressing the Infectious Laryngotracheitis Virus (ILTV) Glycoprotein gB or gD as Dual Vaccines |
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89 | (14) |
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7 A Reverse Genetics Approach for the Design of Methyltransferase-Defective Live Attenuated Avian Metapneumovirus Vaccines |
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103 | (20) |
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8 Development of Fasciola Vaccine in an Animal Model |
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123 | (12) |
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9 Development of Experimental Vaccines Against Liver Flukes |
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135 | (18) |
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10 Towards a Preventive Strategy for Toxoplasmosis: Current Trends, Challenges, and Future Perspectives for Vaccine Development |
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153 | (12) |
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11 DNA Vaccination in Chickens |
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165 | (16) |
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Part III Vaccines for Fishes and Shellfish |
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12 Selection of Vaccine Candidates for Fish Pasteurellosis Using Reverse Vaccinology and an In Vitro Screening Approach |
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181 | (12) |
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13 Development of Vaccines Against Nocardiosis in Fishes |
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193 | (10) |
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14 Design of an Immersion Vaccine Against Aeromonad Septicemia in Perch (Perca fluviatilis L.) |
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203 | (8) |
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15 Prokaryotic Production of Virus-Like Particle Vaccine of Betanodavirus |
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211 | (14) |
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16 Design and Construction of Shrimp Antiviral DNA Vaccines Expressing Long and Short Hairpins for Protection by RNA Interference |
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225 | (18) |
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Part IV Vaccines Against Ticks |
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17 Developing Anti-tick Vaccines |
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243 | (18) |
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18 Host Immunization with Recombinant Proteins to Screen Antigens for Tick Control |
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261 | (14) |
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19 Vaccinomics Approach to Tick Vaccine Development |
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275 | (14) |
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20 Development of CpG ODN Based Vaccine Adjuvant Formulations |
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289 | (12) |
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Part VI Vaccine Vectors and Production Systems |
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21 Assembly and Assessment of DNA Scaffolded Vaccines |
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301 | (12) |
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22 Alphavirus-Based Vaccines |
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313 | (16) |
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23 Vaccine Design: Replication-Defective Adenovirus Vectors |
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329 | (22) |
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24 Generation of Lymphocytic Choriomeningitis Virus Based Vaccine Vectors |
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351 | (14) |
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25 Production of Japanese Encephalitis Virus-Like Particles Using Insect Cell Expression Systems |
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365 | (12) |
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26 Subunit Protein Vaccine Delivery System for Tuberculosis Based on Hepatitis B Virus Core VLP (HBc-VLP) Particles |
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377 | (16) |
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27 Formulation Studies During Preclinical Development of Influenza Hemagglutinin and Virus-Like Particle Vaccine Candidates |
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393 | (30) |
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28 Strategies for Vaccine Design Using Phage Display-Derived Peptides |
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423 | (14) |
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29 Production of Well-Characterized Virus-like Particles in an Escherichia co/j-Based Expression Platform for Preclinical Vaccine Assessments |
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437 | (22) |
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30 Laboratory Scale Production of Recombinant Haa86 Tick Protein in Pichia pastoris and in Escherichia coli System |
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459 | (24) |
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31 Production and Purification of Recombinant Filamentous Bacteriophages Displaying Immunogenic Heterologous Epitopes |
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483 | (14) |
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32 Oral Vaccine Development by Molecular Display Methods Using Microbial Cells |
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497 | (14) |
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33 Facile Method for the Production of Recombinant Cholera Toxin B Subunit in E. coli |
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511 | (8) |
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34 Immunoproteomic Approach for Screening Vaccine Candidates from Bacterial Outer Membrane Proteins |
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519 | (10) |
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35 Construction and Immunogenicity Testing of Whole Recombinant Yeast-Based T-Cell Vaccines |
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529 | (18) |
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36 Oral Rabies Vaccine Design for Expression in Plants |
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547 | (22) |
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37 Purification of Virus-Like Particles (VLPs) from Plants |
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569 | (12) |
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38 Transient Expression of Viral Proteins in Plants Using Agrobacterium tumefaciens |
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581 | (16) |
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39 A Plant-Based Transient Expression System for the Rapid Production of Malaria Vaccine Candidates |
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597 | (24) |
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40 Recombinant Botulinum Toxoids: A Practical Guide for Production |
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621 | (14) |
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Gustavo Marcal S. G. Moreira |
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Carlos Eduardo P. da Cunha |
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Part VII Vaccine Delivery Systems |
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41 Preparation of Multifunctional Liposomes as a Stable Vaccine Delivery-Adjuvant System by Procedure of Emulsification-Lyophilization |
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635 | (16) |
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42 Preparation of the Multifunctional Liposome-Containing Microneedle Arrays as an Oral Cavity Mucosal Vaccine Adjuvant-Delivery System |
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651 | (18) |
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43 Preparation and Characterization of PLGA Encapsulated Protective Antigen Domain 4 Nanoformulation |
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669 | (14) |
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44 Attenuated Salmonella sp. as a DNA Delivery System for Trypanosoma cruzi Antigens |
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683 | (14) |
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45 Poly-ε-caprolactone/Chitosan and Chitosan Particles: Two Recombinant Antigen Delivery Systems for Intranasal Vaccination |
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697 | (18) |
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46 Micro-fractional Epidermal Powder Delivery for Skin Vaccination |
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715 | (12) |
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Part VIII Vaccine Bioinformatics |
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47 A Bioinformatics Method for the Design of Live Attenuated Virus Vaccine Utilizing Host MicroRNA Response Elements |
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727 | (14) |
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48 The Web-Based DNA Vaccine Database DNAVaxDB and Its Usage for Rational DNA Vaccine Design |
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741 | (12) |
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49 MetaMHCpan, A Meta Approach for Pan-Specific MHC Peptide Binding Prediction |
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753 | (8) |
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50 A Cohesive and Integrated Platform for Immunogenicity Prediction |
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761 | (12) |
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Part IX Vaccine Safety and Regulation |
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51 The Regulatory Evaluation of Vaccines for Human Use |
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773 | (18) |
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Part X Vaccine Intellectual Property |
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52 Vaccines and IP Rights: A Multifaceted Relationship |
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791 | (22) |
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53 From the Bench to the Pharmacy: Protecting Innovation During Vaccine Development and Commercialization |
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813 | (22) |
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54 Intellectual Property in Vaccine Innovation: Impact of Recent Patent Developments |
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835 | (14) |
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| Index |
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849 | |
