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Preface to the Fourth Edition. |
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1.1 Reasons for Studying Biostatistics. |
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1.2 Initial Steps in Designing a Biomedical Study. |
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1.3 Common Types of Biomedical Studies. |
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2 Populations and Samples. |
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2.2 Definitions of Types of Samples. |
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2.3 Methods of Selecting Simple Random Samples. |
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2.4 Application of Sampling Methods in Biomedical Studies. |
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3 Collecting and Entering Data. |
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4 Frequency Tables and Their Graphs. |
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4.1 Numerical Methods of Organizing Data. |
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5 Measures of Location and Variability. |
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5.1 Measures of Location. |
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5.2 Measures of Variability. |
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5.3 Sampling Properties of the Mean and Variance. |
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5.4 Considerations in Selecting Appropriate Statistics. |
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5.5 A Common Graphical Method for Displaying Statistics. |
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6 The Normal Distribution. |
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6.1 Properties of the Normal Distribution. |
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6.2 Areas Under the Normal Curve. |
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6.3 Importance of the Normal Distribution. |
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6.4 Examining Data for Normality. |
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7 Estimation of Population Means: Confidence Intervals. |
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7.1 Confidence Intervals. |
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7.2 Sample Size Needed for a Desired Confidence Interval. |
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7.4 Confidence Interval for the Mean, Using the t Distribution. |
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7.5 Estimating the Difference Between Two Means: Unpaired Data. |
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7.6 Estimating the Difference Between Two Means: Paired Comparison. |
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8 Tests of Hypotheses on Population Means. |
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8.1 Tests of Hypotheses for a Single Mean. |
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8.2 Tests for Equality of two Means: Unpaired Data. |
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8.3 Testing for Equality of Means: Paired Data. |
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8.4 Concepts Used in Statistical Testing. |
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8.6 Confidence Intervals Versus Tests. |
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8.7 Correcting for Multiple Testing. |
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8.8 Reporting the Results. |
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9 Variances: Estimation and Tests. |
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9.1 Point Estimates for Variances and Standard Deviations. |
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9.2 Testing Whether Two Variances Are Equal: F Test. |
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10 Categorical Data: Proportions. |
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10.1 Single Population Proportion. |
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10.2 Samples from Categorical Data. |
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10.3 The Normal Approximation to the Binomial. |
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10.4 Confidence Intervals for a Single Population Proportion. |
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10.5 Confidence Intervals for the Difference in Two Proportions. |
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10.6 Tests of Hypothesis for Population Proportions. |
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10.7 Sample Size for Testing Two Proportions. |
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10.8 Data Entry and Analysis Using Statistical Programs. |
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11 Categorical Data: Analysis of Two-Way Frequency Tables. |
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11.1 Different Types of Tables. |
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11.2 Relative Risk and Odds Ratio. |
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11.3 Chi-Square Tests for Frequency Tables: two-by-two Tables. |
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11.4 Chi-Square Tests for Larger Tables. |
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12 Regression and Correlation. |
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12.1 The Scatter Diagram: Single Sample. |
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12.2 Linear Regression: Single Sample. |
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12.3 The Correlation Coefficient for two Variables from a Single Sample. |
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12.4 Linear Regression Assuming the Fixed-X Model. |
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12.5 Other Topics in Linear Regression. |
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13 Nonparametric Statistics. |
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13.2 The Wilcoxon Signed Rank Test. |
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13.3 The Wilcoxon-Mann-Whitney Test. |
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13.4 Spearman’s Rank Correlation. |
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14 Introduction to Survival Analysis. |
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14.1 Survival Analysis Data. |
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14.3 Computing Estimates of f(t), S(t), and h(t). |
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14.4 Comparison of Clinical Life Tables and the Kaplan-Meier Method. |
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14.5 Additional Analyses Using Survival Data. |
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Appendix A: Statistical Tables. |
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Appendix B: Answers to Selected Problems. |
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Appendix C: Computer Statistical Program Resources. |
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C.1 Computer Systems for Biomedical Education and Research. |
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C.2 A Brief Indication of Statistics Computer Program Advances and Some Relevant Publications Since 2000. |
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C.3 Choices of Computer Statistical Software. |
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