| Preface |
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xi | |
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xiii | |
| Introduction |
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1 | (2) |
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1 The Significance of Heterocycles for Pharmaceuticals and Agrochemicals |
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3 | (18) |
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3 | (1) |
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1.2 Heterocycles as Framework of Biologically Active Compounds |
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4 | (2) |
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1.3 Fine-Tuning the Physicochemical Properties with Heterocycles |
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6 | (1) |
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1.4 Heterocycles as Prodrugs |
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6 | (1) |
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1.5 Heterocycles as Peptidomimetics |
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7 | (1) |
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1.6 Heterocycles as Isosteric Replacement of Functional Groups |
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8 | (3) |
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1.7 Heterocycles as Isosteric Replacement of Alicyclic Rings |
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11 | (2) |
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1.8 Heterocycles as Isosteric Replacement of other Heterocyclic Rings |
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13 | (8) |
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16 | (5) |
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21 | (82) |
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23 | (16) |
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23 | (1) |
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23 | (4) |
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27 | (4) |
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31 | (3) |
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2.4.1 Point Mutation in psbA Gene |
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33 | (1) |
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2.4.2 Glutathione Conjugation |
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33 | (1) |
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2.4.3 Metabolic Resistance |
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34 | (1) |
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34 | (1) |
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2.6 Structure-Activity Relationships |
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34 | (5) |
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37 | (2) |
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3 Pyrimidinyl and Triazinylsulfonylurea Herbicides |
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39 | (12) |
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39 | (1) |
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39 | (2) |
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41 | (1) |
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41 | (1) |
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41 | (4) |
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45 | (1) |
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46 | (1) |
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3.6 Structure-Activity Relationship |
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47 | (4) |
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48 | (3) |
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4 Acetohydroxyacid Synthase Inhibiting Triazolopyrimidine Herbicides |
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51 | (10) |
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51 | (1) |
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51 | (2) |
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53 | (2) |
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55 | (1) |
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56 | (1) |
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4.6 Structure-Activity Relationship |
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57 | (4) |
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59 | (2) |
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5 HPPD-Inhibiting Benzoylpyrazole Herbicides |
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61 | (8) |
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61 | (1) |
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61 | (1) |
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62 | (2) |
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64 | (2) |
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66 | (1) |
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5.6 Structure-Activity Relationship |
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66 | (3) |
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68 | (1) |
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6 Pyridyloxyphenoxypropionate Herbicides: Inhibitors of Acetyl-CoA Carboxylase |
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69 | (14) |
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69 | (1) |
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69 | (2) |
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71 | (2) |
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73 | (2) |
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75 | (1) |
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6.6 Structure-Activity Relationships |
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76 | (7) |
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80 | (3) |
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7 Imidazolinone Herbicides |
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83 | (8) |
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83 | (1) |
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83 | (2) |
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85 | (1) |
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86 | (1) |
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86 | (2) |
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7.6 Structure-Activity Relationship |
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88 | (3) |
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89 | (2) |
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8 Protoporphyrinogen-IX-Oxidase-Inhibiting Uracil Herbicides |
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91 | (12) |
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91 | (1) |
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91 | (1) |
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92 | (2) |
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94 | (1) |
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94 | (3) |
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8.6 Structure-Activity Relationship |
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97 | (6) |
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100 | (3) |
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103 | (92) |
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9 Benzimidazole Fungicides |
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105 | (14) |
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105 | (1) |
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105 | (3) |
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108 | (2) |
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110 | (2) |
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112 | (2) |
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9.6 Structure-Activity Relationship |
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114 | (5) |
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116 | (3) |
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10 Morpholine Fungicides for the Treatment of Powdery Mildew |
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119 | (10) |
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119 | (1) |
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119 | (1) |
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120 | (2) |
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122 | (1) |
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123 | (1) |
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10.6 Structure-Activity Relationship |
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124 | (5) |
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126 | (3) |
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11 Sterol Biosynthesis Inhibiting Triazole Fungicides |
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129 | (18) |
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129 | (1) |
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129 | (5) |
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134 | (4) |
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138 | (2) |
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140 | (1) |
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11.6 Structure-Activity Relationship |
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141 | (6) |
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143 | (4) |
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12 Methionine Biosynthesis-Inhibiting Anilinopyrimidine Fungicides |
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147 | (8) |
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147 | (1) |
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147 | (1) |
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148 | (2) |
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150 | (1) |
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151 | (1) |
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12.6 Structure-Activity Relationship |
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151 | (4) |
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153 | (2) |
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13 Phenylpyrrole Fungicides |
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155 | (8) |
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155 | (1) |
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155 | (1) |
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156 | (2) |
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158 | (1) |
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158 | (2) |
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13.6 Structure-Activity Relationship |
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160 | (3) |
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161 | (2) |
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14 Broad-Spectrum Fungicidally Active Pyrimidinyldioxy Strobilurins Inhibiting the Respiratory Chain |
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163 | (12) |
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163 | (1) |
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163 | (2) |
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165 | (1) |
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165 | (3) |
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168 | (1) |
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14.6 Structure-Activity Relationship |
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169 | (6) |
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173 | (2) |
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15 Pyrazole Carboxamide Fungicides Inhibiting Succinate Dehydrogenase |
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175 | (20) |
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175 | (1) |
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175 | (2) |
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177 | (6) |
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183 | (2) |
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185 | (2) |
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15.5.1 The Foliar Pyrazole Carboxamides |
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185 | (1) |
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15.5.2 The Seed Treatment Pyrazole Carboxamides |
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186 | (1) |
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15.6 Structure-Activity Relationships |
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187 | (8) |
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191 | (4) |
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191 | (4) |
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195 | (84) |
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16 Avermectin Insecticides and Acaricides |
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197 | (12) |
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197 | (1) |
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197 | (2) |
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199 | (2) |
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201 | (1) |
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202 | (2) |
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16.6 Structure-Activity Relationship |
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204 | (5) |
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206 | (3) |
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17 Pyridine and Thiazole-Containing Insecticides as Potent Agonists on Insect Nicotinic Acetylcholine Receptors |
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209 | (16) |
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209 | (1) |
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209 | (2) |
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211 | (3) |
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214 | (1) |
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215 | (2) |
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17.6 Structure-Activity Relationship |
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217 | (8) |
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221 | (4) |
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18 Pyrazole and Pyrimidine Acaricides and Insecticides Acting as Inhibitors of Mitochondrial Electron Transport at Complex I |
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225 | (14) |
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225 | (1) |
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225 | (2) |
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227 | (2) |
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229 | (1) |
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230 | (1) |
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18.6 Structure-Activity Relationship |
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230 | (9) |
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236 | (3) |
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19 Phenylpyrazole-Containing Fiprole Insecticides |
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239 | (12) |
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239 | (1) |
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239 | (2) |
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241 | (3) |
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244 | (1) |
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244 | (2) |
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19.6 Structure-Activity Relationship |
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246 | (5) |
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248 | (3) |
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20 Pyrazolylpyridine Activators of the Insect Ryanodine Receptor |
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251 | (14) |
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251 | (1) |
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251 | (2) |
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253 | (1) |
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254 | (1) |
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255 | (1) |
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20.6 Structure-Activity Relationships |
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256 | (9) |
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256 | (1) |
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20.6.2 R1 (6-Substituent of the Anthranilic Ring) |
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257 | (1) |
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20.6.3 R2 (4-Substituent of the Anthranilic Ring) |
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257 | (1) |
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20.6.4 R3 (Amide Residue) |
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257 | (1) |
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20.6.5 R4 (3-Pyrazole Substituent) |
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258 | (1) |
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20.6.6 R5 and A (N-Substituted Aryl or Heteroaryl Group) |
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258 | (1) |
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258 | (4) |
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262 | (3) |
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21 Tetronic Acid Insecticides and Acaricides Inhibiting Acetyl-CoA Carboxylase |
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265 | (14) |
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265 | (1) |
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265 | (3) |
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268 | (1) |
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269 | (2) |
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271 | (3) |
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21.6 Structure-Activity Relationship |
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274 | (5) |
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277 | (2) |
| Index |
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