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Current and Future Immunosuppressive Therapies Following Transplantation 2001 ed. [Hardback]

  • Format: Hardback, 388 pages, height x width: 235x155 mm, weight: 757 g, IX, 388 p., 1 Hardback
  • Pub. Date: 30-Sep-2001
  • Publisher: Springer-Verlag New York Inc.
  • ISBN-10: 1402000189
  • ISBN-13: 9781402000188
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  • Format: Hardback, 388 pages, height x width: 235x155 mm, weight: 757 g, IX, 388 p., 1 Hardback
  • Pub. Date: 30-Sep-2001
  • Publisher: Springer-Verlag New York Inc.
  • ISBN-10: 1402000189
  • ISBN-13: 9781402000188
Other books in subject:
This title provides a comprehensive and state-of-the-art summary of current and future immunosuppressive strategies in transplantation, with emphasis on the basic science mechanisms and clinical applicability of these strategies. The uniqueness of this book is the inclusion of up-to-date information on the basic mechanisms of actions of the immunosuppressive drugs as well as a summary of the clinical trials data and the potential use of these drugs in clinical organ transplantation. In addition to describing the various immunosuppressive strategies, the book has three special features, including immunosuppression in xenotransplantation, gene therapy approaches, and transplantation tolerance. A group of outstanding investigators have been assembled to write the chapters. The book is intended for the transplant professional and the specialist who wants to stay abreast of the current status of immunosuppression in organ transplantation. The book is also useful for basic scientists who work in the field of transplantation immunology.

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Springer Book Archives
Contributors List xii Introduction 1(40) The History of Immunosuppression for Organ Transplantation 3(16) Johnny C. Hong Barry D. Kahan Clinical Trials in Transplant Immunosuppression: What Have We Learned? 19(22) P. Schnuelle F. J. van der Wounde Pharmacological Immunosuppression 41(144) Pharmacologic Monitoring of Immunosuppressive Drugs 43(18) F. Gaspari N. Perico G. Remuzzi Use of Corticosteroids in Kidney Transplantation 61(24) Donald E. Hricik Mycophenolate Mofetil and Azathioprine 85(26) John D. Pirsch Elias David Neto Cyclosporine Formulations 111(12) V. Ramanathan Hal Helderman Tacrolimus 123(20) Ron Shapiro Sirolimus 143(22) Barry D. Kahan New Agents on the Horizon 165(20) J. Klupp Randall E. Morris Biologicals 185(130) Why Do We Need Induction Therapy? 187(18) John Vella John Neylan Polyclonal Antilymphocyte Therapy 205(16) Paul Morrissey Anthony P. Monaco Monoclonal Antibody Targeting of the T cell Receptor Complex 221(14) Luciene Chatenoud Monoclonal Antibody Targeting of IL-2R-Complex 235(14) Flavio G. Vincenti Monoclonal Antibody Targeting of Adhesion Molecules 249(16) Marcus H. Frank David M. Briscoe Costimulation Blocade 265(14) Roy D. Bloom Laurence A. Turka Immunomodulatory Function of MHC Peptides 279(14) Barbara Murphy Alan Krensky Tolerance: Is It Time to Move to the Clinic? 293(22) Markus H. Frank Mohamed H. Sayegh Gene Therapy 315(42) Molecular Medicine in Organ Transplantation: How and When? 317(18) A. Benigni N. Perico G. Remuzzi Gene Therapy in Organ Transplantation: Applicabilities and Shortcomings 335(22) John C. Magee Randall S. Sung J. Bromberg Immunomodulation Strategies in Xenotransplantation 357 Ian P.J. Alwayn Leo Buhler Murali Basker David K.C. Cooper