| Contributors |
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vii | |
| Foreword |
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| Abbreviations |
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xii | |
| Part 1: Overview: From Basic Research to Caring for the Laminitis Patient |
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1 Historical Perspective on Equine Laminitis |
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3 | (8) |
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11 | (2) |
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3 Anatomy and Function of the Equine Digit |
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13 | (9) |
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4 Lamellar Function at the Cellular Level |
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22 | (17) |
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5 Digital Biomechanics Relevant to Laminitis |
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39 | (12) |
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| Part 2: Pathophysiology of Laminitis |
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51 | (3) |
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7 Experimental Models of Laminitis: Starch Overload |
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54 | (5) |
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8 Experimental Models of Laminitis: Oligofructose Overload |
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59 | (5) |
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9 Experimental Models of Laminitis: Black Walnut Extract |
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64 | (4) |
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10 Experimental Models of Laminitis: Hyperinsulinemia |
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68 | (7) |
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11 Hemodynamic Events in Laminitis |
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75 | (7) |
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12 The Role of Thrombosis and Coagulation in Equine Laminitis |
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82 | (9) |
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13 Leukocytes and Inflammatory Signaling in Laminitis: Leukocytes |
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91 | (11) |
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14 Leukocytes and Inflammatory Signaling in Laminitis: Inflammatory Signaling |
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102 | (13) |
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15 Role of Proteases in Laminitis |
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115 | (19) |
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16 Endocrine and Metabolic Dysregulation in Laminitis: Role of Pituitary Dysfunction |
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134 | (7) |
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17 Endocrine and Metabolic Dysregulation in Laminitis: Role of Corticosteroids |
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141 | (8) |
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18 Metabolic Syndrome in Humans and Horses: The Relationship Between Obesity and Insulin Resistance |
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149 | (18) |
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19 Dysregulation of the Lamellar Basal Epithelial Cell in Laminitis: Role of the Cytoskeleton and Cell Junctions |
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167 | (9) |
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20 Structural Dynamics of Displacement of the Distal Phalanx |
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176 | (7) |
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| Part 3: Clinical Presentation of Equine Laminitis |
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21 General Clinical Aspects of the Laminitis Case |
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183 | (8) |
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22 Sepsis-Related Laminitis |
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191 | (5) |
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23 Laminitis in Equine Metabolic Syndrome |
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196 | (8) |
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24 Laminitis in Pituitary Pars Intermedia Dysfunction |
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204 | (6) |
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25 Supporting Limb Laminitis |
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210 | (7) |
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| Part 4: Diagnostic Evaluation of Equine Laminitis |
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26 Detailed Physical Examination for Laminitis |
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217 | (9) |
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226 | (14) |
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240 | (12) |
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29 Endocrine and Metabolic Evaluation in Horses with Laminitis |
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252 | (17) |
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| Part 5: Medical Treatment of the Laminitic Patient |
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30 General Supportive Care for the Laminitis Case |
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269 | (8) |
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31 Common Therapies: Anti-Inflammatory Therapy |
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277 | (7) |
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32 Vasoactive Drug Therapy |
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284 | (7) |
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291 | (15) |
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306 | (10) |
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316 | (13) |
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36 Equine Metabolic Syndrome |
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329 | (5) |
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37 Pituitary Pars Intermedia Dysfunction |
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334 | (9) |
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| Part 6: Treatment of Laminitis: Digital Support and Stabilization of the Distal Phalanx |
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38 Therapeutic Shoes: Application of Principles |
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343 | (11) |
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39 Solear Support Techniques |
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354 | (6) |
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40 Approaching Digital Management Prior to Displacement of the Distal Phalanx |
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360 | (4) |
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41 Hoof Care Management of Horses with Displacement of the Distal Phalanx |
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364 | (13) |
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| Part 7: Treatment of the Laminitis Case |
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42 The Use of Casts in Equine Laminitis |
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377 | (5) |
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43 Deep Digital Flexor Tenotomy |
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382 | (9) |
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44 Dorsal Hoof Wall Techniques |
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391 | (11) |
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45 Complications of Laminitis |
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402 | (11) |
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| Part 8: Management of Chronic Laminitis |
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46 Management Changes in the Laminitis Case |
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413 | (10) |
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| Part 9: Prevention of Laminitis |
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47 Overview of Laminitis Prevention |
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423 | (4) |
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48 Prevention of Supporting Limb Laminitis |
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427 | (5) |
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49 Prevention of Sepsis-Related Laminitis |
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432 | (4) |
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50 Nutritional Management for Avoidance of Pasture-Associated Laminitis |
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436 | (6) |
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| Glossary |
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442 | (3) |
| Index |
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445 | |
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