Covering the manufacture of optimized formulations, commercial forms, and forms for applications, this book for formulation chemists and chemical engineers examines the separate disciplines that play a role in the formulation of an active ingredient into its commercial form, with special emphasis on colloid and surface chemistry and the establishment of an interdisciplinary theory of formulation technology. Treatment is independent of individual products and of substance-specific formulation problems. Coverage encompasses basic physico-chemical theory as well as its applications in the chemical industry for the production of pharmaceuticals, agrochemicals, pigments and dyes, food, detergents, cosmetics, and other products. Annotation c. Book News, Inc., Portland, OR (booknews.com)
Many chemical substances or compounds - organic or inorganic, natural or synthetic - are not used in their pure form. In order for the active ingredient to be most effective or to obtain the ideal delivery form for the market, the actual synthesis and purification steps are followed by formulation to give end products that range from powders, agglomerates, and granules to suspensions, emulsions, microemulsions, microcapsules, instant preparations, liposomes, and tablets.
Formulation combines colloid and surface chemistry with chemical process engineering; sometimes it consists of a simple mixing operation, sometimes it requires an entire series of rather complicated engineering procedures such as comminution, dispersion, emulsification, agglomeration or drying.
This book covers basic physico-chemical theory as well as its applications in the chemical industry for the production of pharmaceuticals, agrochemicals, pigments and dyes, food, detergents, cosmetics and many other products; it also provides chemists and chemical engineers with the necessary practical tools for the understanding of the structure/ activity relationship.