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E-raamat: Ischemic Penumbra [Taylor & Francis e-raamat]

Edited by (Addenbrooke's Hospital, Cambridge, UK), Edited by , Edited by (University of California, Davis, California, USA), Edited by
  • Formaat: 344 pages, 133 Halftones, black and white; 29 Tables, black and white; 57 Illustrations, color; 197 Illustrations, black and white, Contains 93 hardbacks
  • Sari: Neurological Disease and Therapy
  • Ilmumisaeg: 13-Apr-2007
  • Kirjastus: Informa Healthcare
  • ISBN-13: 9780429116735
Teised raamatud teemal:
  • Taylor & Francis e-raamat
  • Hind: 249,27 €*
  • * hind, mis tagab piiramatu üheaegsete kasutajate arvuga ligipääsu piiramatuks ajaks
  • Tavahind: 356,10 €
  • Säästad 30%
  • Formaat: 344 pages, 133 Halftones, black and white; 29 Tables, black and white; 57 Illustrations, color; 197 Illustrations, black and white, Contains 93 hardbacks
  • Sari: Neurological Disease and Therapy
  • Ilmumisaeg: 13-Apr-2007
  • Kirjastus: Informa Healthcare
  • ISBN-13: 9780429116735
Teised raamatud teemal:
The Ischemic Penumbra presents the current status of concepts and research on this topic and identifies the latest methods for clinicians to quickly and efficiently recognize viable cerebral tissue for enhanced stroke management. Focusing on state-of-the-science technologies and current trends, the book examines imaging strategies utilizing PET, SPECT, MR, and CT for improved identification of key areas for intervention and therapy in the management of stroke patients.









With chapters by international authorities on the topicincluding the originator of the ischemic penumbra concept, Professor Lindsay Symonthis volume provides a comprehensive view of the ischemic penumbra ranging from neurochemical processes to clinical implications, imaging, and therapy. It contains the first authoritative discussion of the thresholds and duration of the ischemic penumbra documented in various species, with sections that outline cerebral blood flow levels and their effects on important biochemical parameters. The book also supplies an authoritative series of chapters individually focused on current imaging techniques to target the location and extent of the penumbra. It outlines the relevance of the ischemic penumbra to specific therapies, such as extending time windows for therapy, and studies the determination of the presence of penumbra using a novel imaging/clinical mismatch concept, with clinical evidence and validation to date.
Foreword v
Werner Hacke
Preface vii
Contributors xi
Section I: The Ischemic Penumbra: An Overview
The Ischemic Penumbra---The Beginning
1(6)
Lindsay Symon
The Ischemic Penumbra: Overview, Definition, and Criteria
7(14)
Geoffrey A. Donnan
Jean-Claude Baron
Stephen M. Davis
Frank R. Sharp
Perfusion Thresholds in Cerebral Ischemia
21(16)
Ramez R. Moustafa
Jean-Claude Baron
Duration and Thresholds of the Ischemic Penumbra in Different Species
37(22)
Omar Touzani
Jean-Claude Baron
The Ischemic Cascade: Events Within the Penumbra
59(18)
Juliane Klehmet
Ulrich Dirnagl
Jens Peter Dreier
Andreas Meisel
Multimodal Mapping of the Ischemic Penumbra in Animal Models
77(16)
Konstantin-A. Hossmann
Gunter Mies
Molecular Biology of the Penumbra
93(16)
Frank R. Sharp
Huichun Xu
Xinshe Liu
Ruiqiong Ran
Selective Neuronal Loss
109(16)
Anthony J. Strong
Anna M. Planas
Inflammation and Reperfusion Injury Within the Penumbra
125(12)
Adrian Parry-Jones
Johann R. Selvarajah
Pippa J. Tyrrell
Nancy J. Rothwell
Section II: Imaging the Penumbra: Other Approaches
Imaging Penumbra and Neuronal Loss: Positron Emission Tomography with Flumazenil
137(12)
Wolf-Dieter Heiss
Jan Sobesky
Alexander Thiel
Christian Dohmen
Bernd Bauer
Karl Wienhard
Rudolf Graf
Imaging the Penumbra: Positron Emission Tomography Fluoromisonidazole
149(16)
Neil J. Spratt
David W. Howells
Geoffrey A. Donnan
Can the Penumbra Be Imaged Using Single-Photon Emission Computed Tomography?
165(12)
Toshihiro Ueda
Magnetic Resonance Imaging Assessment of the Ischemic Penumbra in Experimental Stroke
177(10)
Timothy Q. Duong
Marc Fisher
Penumbra Imaged with Magnetic Resonance Imaging in Humans
187(10)
Chelsea S. Kidwell
Steven Warach
Perfusion Computed Tomography and Xenon-Computed Tomography: Current Status and Implications for Therapy
197(22)
Perfusion Computed Tomography
197(10)
Patrik Michel
Max Wintermark
Julien Bogousslavsky
Xenon-Computed Tomography-Cerebral Blood Flow Assessment of Ischemic Penumbra in Acute Stroke
207(12)
Tudor G. Jovin
Lawrence R. Wechsler
Rishi Gupta
Howard Yonas
Magnetic Resonance Imaging of Ischemic Penumbra: New Techniques
219(22)
Gradient Echo
219(3)
Jun Hatazawa
Eku Shimosegawa
``Penumbra'' Defined by Magnetic Resonance Imaging: Oxygen Extraction Fraction and Cerebral Metabolic Rate of Oxygen Utilization
222(12)
Weili Lin
Hongyu An
Yang Wu
Quan Zhu
Katie Vo
Jin-Moo Lee
Chung Y. Hsu
Arterial Spin Labeling
234(7)
John A. Detre
Timothy Q. Duong
Clinical/Imaging Mismatch as an Index of the Penumbra
241(10)
Jane F. Prosser
Antoni Davalos
Stephen M. Davis
The Topography of the Ischemic Penumbra
251(12)
Romesh Markus
David Reutens
Geoffrey A. Donnan
The Penumbra and Intracerebral Hemorrhage
263(18)
Ken Butcher
Romesh Markus
Section III: The Ischemic Penumbra: Implications for Therapy
Extending the Time Window for Therapy
281(26)
Numthip Chitravas
Geoffrey A. Donnan
Magnetic Resonance in the Selection of Stroke Therapies
307(10)
Stephen M. Davis
Joachim Rother
Geoffrey A. Donnan
Index 317