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E-raamat: Kidney: Toxicological Assessment [Taylor & Francis e-raamat]

Edited by (Seoul National University, South Korea)
  • Formaat: 234 pages, 1 Tables, color; 13 Illustrations, color; 30 Illustrations, black and white
  • Ilmumisaeg: 11-Sep-2013
  • Kirjastus: CRC Press Inc
  • ISBN-13: 9780429074172
  • Taylor & Francis e-raamat
  • Hind: 230,81 €*
  • * hind, mis tagab piiramatu üheaegsete kasutajate arvuga ligipääsu piiramatuks ajaks
  • Tavahind: 329,73 €
  • Säästad 30%
  • Formaat: 234 pages, 1 Tables, color; 13 Illustrations, color; 30 Illustrations, black and white
  • Ilmumisaeg: 11-Sep-2013
  • Kirjastus: CRC Press Inc
  • ISBN-13: 9780429074172
"This book bridges the gap between advances in basic biology and chemistry and technological applications in the field of toxicity assessments. 10 chapters describe major areas of progress in the laboratory and clinic. In the first section, the aspects of cellular organelles are discussed. In the second, the basic principles and applications of modern toxicological tools such as transcriptomic, proteomic, and metabolomic approaches are covered. In the third section, the recent developments on molecular modeling and systems biology are described with an eye on the future establishment of virtual cell technology. Finally the clinical implications for the understanding of acute and chronic renal toxicity are studied"--Provided by publisher.

This book bridges the gap between advances in basic biology and chemistry and technological applications in the field of toxicity assessments. 10 chapters describe major areas of progress in the laboratory and clinic. In the first section, the aspects of cellular organelles are discussed. In the second, the basic principles and applications of modern toxicological tools such as transcriptomic, proteomic, and metabolomic approaches are covered. In the third section, the recent developments on molecular modeling and systems biology are described with an eye on the future establishment of virtual cell technology. Finally the clinical implications for the understanding of acute and chronic renal toxicity are studied.

Preface v
Contributors ix
Section I
1 Cellular Organelle-based Renal Toxicity
3(18)
Young-Jin Chun
Section II
2 Transcriptomic Approaches to Toxicity Assessment
21(21)
Dal Woong Choi
Woonun Jung
Il Je Cho
Min Sung Joo
Chan Gyu Lee
Sang Woo Lim
Sang Geon Kim
3 Proteomic Approaches to Toxicity Assessment
42(35)
Sun Young Kim
So Jung Son
Aree Moon
4 A Metabolomics Approach for Evaluation of Target-organ
77(26)
Toxicity Kyu-Bong Kim
A fin Won
Suhkmann Kim
Byung Mu Lee
Hyung Sik Kim
Section III
5 In Silico Approaches to Study Drug-induced Renal Toxicity
103(18)
Rajiv Gandhi Govindaraj
Prasannavenkatesh Durai
Sangdun Choi
6 Systems Toxicology Approaches
121(19)
Hyobin Jeong
Sang Chul Rho
Daehee Hwang
7 Introduction to Virtual Cell and its Possible Application to Toxicity
140(19)
Ji-Young Hong
Eun Bo Shim
Kwang Hyun Cho
Section IV
8 Molecular Pathology of Renal Fibrosis
159(16)
Inah Hwang
Joo young Huh
Hunjoo Ha
9 Clinical Implications of Renal Toxicity
175(16)
Duk-Hee Kang
Section V
10 Classification of Nephrotoxicants
191(14)
Hang-Sik Roh
Jong-Kwon Lee
Tae-Sung Kim
Ji-Hyeon Seok
Ji-Hyun Yun
Ji-Young Yun
Saet-Byul Oh
Soon-Young Han
Jayoung Jeong
Index 205(6)
Color Plate Section 211
Kim, Sang Geon