Presents 14 contributions addressing the chemistry, pharmacology, mode of action, target animal safety, environmental impact, efficacy, and resistance of all the macrocyclic lactones with highlights of information on the use of MLs to control parasites in target animals particularly cattle, sheep, goats, horses, swine, dogs, cats, domesticated wild ruminants, man, mammalian pets, and non-mammalians. The first five chapters offer a general review of the MLs, followed by eight chapters which focus on the specific use of MLs for particular hosts. Suitable for researchers in antiparasitics and fields researchers involved in parasite control, as well as practicing veterinarians. Distributed by Oxford University Press. Annotation (c) Book News, Inc., Portland, OR (booknews.com)
Macrocyclic lactones are chemical compounds that represent the main treatment for parasitic diseases of animals, not only for helminth infections, but also a number of major ectoparasitic infestations. There has been no comprehensive book on this subject for more than a decade. This book fills this gap and provides detailed coverage of the basic science of these drugs and their mode of action, as well as their clinical use in farm and companion animals and in humans. Contents include: Chemistry and mode of action; pharmacology, toxicology and efficacy; use in large and small animals and in humans; and resistance against MLs.
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