Fernandez-Botran and Vetvicka (both, pathology, U. of Louisville, Kentucky) provides a tool for laboratory investigators using cellular immunological techniques in their research, whether or not immunology is their main area of expertise. Step-by-step they address background information, alternative techniques, potential limitations or pitfalls, and other useful information. They do not mention a date for the first edition, but have deleted some techniques no longer in use; updated others; and added new information and methodology, especially pertaining to novel cytokines and chemokines. The plastic claw binding lies open flat. Annotation c. Book News, Inc., Portland, OR (booknews.com)