Microneedles provide an artificial pathway across the skin barrier for medical and cosmetic applications. This technology has seen a significant increase in popularity over the past years; as an example, the use of multiple small needles mounted on a roller to pierce the skin, prompting it to stimulate collagen production, has undergone a resurgence of interest as an adjunctive procedure for a number of skin disorders. This monograph draws together what is known about how to integrate microneedle technology into clinical dermatologic practice.
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vii | |
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1 Microneedles and Transdermal Transport |
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1 | (6) |
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2 Skin Perforation and Solid Microneedles |
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7 | (12) |
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3 Dissolvable and Coated Microneedle Arrays: Design, Fabrication, Materials, and Administration Methods |
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19 | (16) |
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35 | (14) |
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5 Microneedles vs. Other Transdermal Technologies |
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49 | (16) |
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6 Combination of Microneedles with Other Methods |
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65 | (10) |
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7 Medical Applications of Microneedles |
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75 | (6) |
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8 Therapeutic Drug and Biomolecule Monitoring Potential for Microneedle Technologies |
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81 | (10) |
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Sahan A. Ranamukhaarachchi |
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9 Commercialized Microneedles |
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91 | (18) |
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10 Considerations for Clinical Trials Involving Microneedle Devices |
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109 | (10) |
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11 Microneedling in Clinical Practice: Cosmetic applications |
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119 | (14) |
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12 Dermatotoxicology of Microneedles in Man |
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133 | (12) |
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| Index |
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145 | |
Boris Stoeber, PEng, PhD is Professor, Mechanical Engineering and Electrical and Computer Engineering, Research Chair in Microfluidics and Sensing Technology, Faculty of Applied Science, University of British Columbia, Vancouver
Raja K Sivamani, MD, MS (Bioengineering), AP is Ayurvedic Practitioner, Pacific Skin Institute; Adjunct Associate Professor of Clinical Dermatology, Director of Clinical Research, University of California, Davis; Associate Professor of Dermatology, California Northstate University, College of Medicine; and Adjunct Assistant Professor, Co-Director of Microbiome Labs Research Initiative, Department of Biological Sciences, California State University, Sacramento
Howard I. Maibach, MD is Professor, Dermatology, School of Medicine, University of California at San Francisco
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