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E-raamat: NMR in Structural Biology: A Collection of Works by Kurt Wuthrich [World Scientific e-raamat]

Edited by (The Scripps Research Inst, Usa & Eth Zurich, Switzerland)
  • World Scientific e-raamat
  • Hind: 175,56 €*
  • * hind, mis tagab piiramatu üheaegsete kasutajate arvuga ligipääsu piiramatuks ajaks
The volume presents a survey of the research by Kurt Wüthrich and his associates during the period 1965 to 1994. A selection of reprints of original papers on the use of NMR spectroscopy in structural biology is supplemented with an introduction, which outlines the foundations and the historical development of the use of NMR spectroscopy for the determination of three-dimensional structures of biological macromolecules in solution. The original papers are presented in groups highlighting protein structure determination by NMR, studies of dynamic properties and hydration of biological macromolecules, and practical applications of the NMR methodology in fields such as enzymology, transcriptional regulation, immunosuppression and protein folding.
NMR and structural biology; the avenue to three-dimensional protein
structure determination in solution; establishing credibility for NMR
structures of proteins; evolution of NMR structure determination with
biological macromolecules 1985-94; selected NMR structure determinations;
confirmational equilibria and internal mobility in proteins in solution;
hydration of proteins and nucleic acids in solution; protein folding; and
seven appendices.