Muutke küpsiste eelistusi

E-raamat: Story of Interferon: Ups and Downs in the Life of a Scientist [World Scientific e-raamat]

  • Formaat: 252 pages
  • Ilmumisaeg: 21-May-1998
  • Kirjastus: World Scientific Publishing Co Pte Ltd
  • ISBN-13: 9789812817013
  • World Scientific e-raamat
  • Hind: 47,12 €*
  • * hind, mis tagab piiramatu üheaegsete kasutajate arvuga ligipääsu piiramatuks ajaks
  • Formaat: 252 pages
  • Ilmumisaeg: 21-May-1998
  • Kirjastus: World Scientific Publishing Co Pte Ltd
  • ISBN-13: 9789812817013
The Finnish doctor Kari Cantell is one of the scientists to whom the development of the drugs called interferons can be attributed. Interferons have achieved an important place in the treatment of cancer, viral infections and multiple sclerosis. In the 1960s Cantell and his coworkers developed a method for the preparation of interferon in white blood cells. During those years, most of the global production of interferon took place in Finland and the vast majority of the clinical studies in the world employed Finnish interferon.The memoirs of Cantell record interferon's long road from the laboratory to the pharmacy shelf. The journey took more than three decades and involved moments of triumph as well as desperation in the lives of many scientists.The book will give the reader a glimpse of the world of science; how research is carried out in the laboratory and the clinic; how the mind of the scientist operates and how he experiences success and failure; how warm friendships and bitter conflicts develop between investigators; how the involvement of money and politics harms as well as helps research.The Interferon Story is a richly rewarding book written for ordinary people without a basic knowledge of biology or medicine. It can be read as a thriller describing the struggle of scientists against the most feared diseases of mankind.
Preface vii
The way through an impasse
1(3)
Chance
4(3)
Into the world of laboratory life
7(3)
I become involved with mumps virus
10(4)
Interferon comes on the scene
14(4)
My thesis -- and other matters!
18(3)
Should I become a scientist?
21(5)
To the New World
26(3)
An embarrassing episode
29(2)
The Henles' laboratory in Philadelphia
31(2)
My Jewish friend, Kurt
33(4)
Working with Kurt
37(6)
Great and small prophets
43(3)
Back home again
46(5)
Chick interferon
51(3)
Human interferon
54(5)
Tapani Vainio
59(3)
Hans and Gyurka
62(4)
How much interferon can be prepared in human white cells?
66(6)
Harri Nevanlinna
72(3)
The shadow of Maurice Hilleman
75(7)
The yardstick
82(4)
Competitors
86(4)
Against the current
90(7)
The lesson from animal experiments
97(3)
Eureka!
100(8)
From the laboratory to the clinic
108(11)
Double-blind
119(3)
Interest in interferons increases
122(9)
Things start to move
131(5)
Is it difficult to grind a barrel organ?
136(5)
The Cubans
141(9)
Why is interferon not in clinical use today?
150(4)
Namalwa
154(11)
A phone call from Zurich
165(11)
I miss a "moment of decision"
176(4)
The value of a scientific observation
180(5)
New information about interferons
185(6)
Mathilde, once again!
191(4)
Interferon becomes a superstar
195(7)
Who will get interferon?
202(8)
Interferon in the eye
210(7)
Interferon in the nose
217(8)
The breakthrough
225(8)
Finnferon-alpha
233(5)
Interferons as drugs today and tomorrow
238(2)
Acknowledgements 240