With all the issues of acceptance or rejection of a transplanted organ, immunology is a core subject for all translantation clinicians.
With all the complex issues of acceptance or rejection of a transplanted organ, immunology is a key subject for all transplantation clinicians. During recent years, there has been an explosion of research and knowledge in this area.
Produced in association with the American Society of Transplantation, and written by experts within the field, Transplant Immunology provides a comprehensive overview of the topic in relation to clinical transplantation.
Starting with the basic functionality of the immune system, it then moves on to cover the very latest developments in immunosupressive drugs and protocols, as well as a look at all emerging technologies in the field.
Key chapters include:
Transplant-related complications
- Immune responses to transplants
- Emerging issues in transplantation
- Biomarkers of Allograft rejection and tolerance
- T cells and the principles of immune responses
In full colour throughout, over 100 outstanding diagrams support the text, all figures being fully downloadable via the book's companion website. The result is an essential tool for all those responsible for managing patients awaiting and undergoing organ transplantation, including transplant surgeons and clinicians, immunologists and researchers.
| Contributors |
|
vii | |
| Foreword |
|
xii | |
| Preface |
|
xiv | |
| About the companion website |
|
xv | |
|
1 Tissues and organs of the immune system |
|
|
1 | (24) |
|
|
|
|
|
|
|
2 Cells of the immune system |
|
|
25 | (23) |
|
|
|
|
|
|
|
|
|
|
|
3 Soluble mediators in the immune system |
|
|
48 | (17) |
|
|
|
|
|
|
|
4 Costimulatory molecules |
|
|
65 | (20) |
|
|
|
|
|
5 Major histocompatibility complex |
|
|
85 | (18) |
|
|
|
|
|
|
|
|
|
6 T cells and the principles of immune responses |
|
|
103 | (25) |
|
|
|
|
|
|
|
7 Ischemia and reperfusion injury |
|
|
128 | (14) |
|
|
|
|
|
|
|
|
|
Jerzy W. Kupiec-Weglinski |
|
|
8 Immune responses to transplants |
|
|
142 | (22) |
|
|
|
|
|
9 Principles of hematopoietic cell transplantation |
|
|
164 | (20) |
|
|
|
|
|
10 Therapeutic approaches to organ transplantation |
|
|
184 | (33) |
|
|
|
|
|
|
|
|
|
|
|
11 Organ-specific features in clinical transplantation |
|
|
217 | (20) |
|
|
|
12 Transplant-related complications |
|
|
237 | (22) |
|
|
|
|
|
13 Biomarkers of allograft rejection and tolerance |
|
|
259 | (21) |
|
|
|
|
|
|
|
14 Emerging issues in transplantation |
|
|
280 | (17) |
|
|
|
|
|
|
|
|
|
15 New frontiers and new technologies |
|
|
297 | (19) |
|
|
|
|
|
|
|
|
|
16 Experimental models in discovery and translational studies |
|
|
316 | (21) |
|
|
|
|
|
|
| Index |
|
337 | |
Xian C. Li, MD, PhD, Professor of Immunology/surgery, Weill Cornell Medical College, Cornell University, New York, NY; and Director, Immunobiology and Transplant Science, Houston Methodist Hospital, Texas Medical Center, Houston, TX, USA.
Anthony M. Jevnikar MSc (Immunology), MD, FRCP(C), Professor of Medicine, Surgery, Immunology and Microbiology, Western University, Director Transplantation Nephrology and Director Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre, London ON, Canada.
Rohkem infot Wiley Online kohta