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E-raamat: Bone and Joint Infections - From Microbiology to Diagnostics and Treatment, Second Edition: From Microbiology to Diagnostics and Treatment 2nd Edition [Wiley Online]

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  • Formaat: 464 pages
  • Ilmumisaeg: 29-Apr-2021
  • Kirjastus: Wiley-Blackwell
  • ISBN-10: 1119720672
  • ISBN-13: 9781119720676
Teised raamatud teemal:
  • Wiley Online
  • Hind: 256,87 €*
  • * hind, mis tagab piiramatu üheaegsete kasutajate arvuga ligipääsu piiramatuks ajaks
Bone and Joint Infections - From Microbiology to Diagnostics and Treatment, Second Edition: From Microbiology to Diagnostics and Treatment 2nd EditionSuurem pilt
  • Formaat: 464 pages
  • Ilmumisaeg: 29-Apr-2021
  • Kirjastus: Wiley-Blackwell
  • ISBN-10: 1119720672
  • ISBN-13: 9781119720676
Teised raamatud teemal:
Wiley Online e-raamatudRohkem infot Wiley Online kohta
Raamatu kodulehekülg: https://onlinelibrary.wiley.com/doi/book/10.1002/9781119720676
BONE AND JOINT INFECTIONS

Explore this comprehensive presentation of bone and joint infections, including non-implant and implant-associated orthopedic infections

In the newly revised Second Edition of Bone and Joint Infections: From Microbiology to Diagnostics and Treatment, accomplished researcher and author Werner Zimmerli delivers a comprehensive overview of the most recent developments in the subject of bone and joint infection. Covering much of the new information appearing over the last five years, the book includes four new chapters presenting the diagnostic approach in bone and joint infections, discussing the identification of pathogens by non-culture techniques, management of multi-resistant bacteria in bone and joint infections ­by bacteriophages, and unusual microorganisms in periprosthetic joint infections.

Many of the chapters are also updated to include new information on topics like eubacterial PCR, multiplex PCR, and the shotgun metagenomics approach. These subjects are of increased applicability and interest to increase the fraction of cases with identified pathogens. The book also helps clinicians to understand MRI-based images and rapidly interpret and plan for comprehensive therapy.

Readers will also benefit from the inclusion of:

  • A thorough introduction to the pharmacokinetics and pharmacodynamics of antibiotics in bone and preclinical models of infection in bone and joint surgery
  • An exploration of native joint arthritis in children and adults, as well as an overview of septic arthritis of axial joints
  • A practical discussion of the general aspects of periprosthetic joint infection, as well as specific aspects of periprosthetic joint infection after total hip and knee, shoulder, elbow, and ankle arthroplasty
  • A concise treatment of osteomyelitis in children and adults

Perfect for infectious disease specialists, microbiologists, orthopedic and trauma surgeons, and internists, Bone and Joint Infections: From Microbiology to Diagnostics and Treatment will also earn a place in the libraries of professionals working in the implant industry and pharmaceuticals, as well as clinical pharmacologists and rheumatologists.

List of Contributors xii
Preface to the Second Edition xvi
Foreword to the First Edition xvii
Acknowledgments xix
Chapter 1 Introduction 1(4)
Werner Zimmerli
Chapter 2 Diagnostic Approach in Bone and Joint Infections 5(16)
Nora Renz
Donara Margaryan
Andrej Trampuz
Introduction
5(2)
Common Microorganisms Causing Bone and Joint Infection
7(1)
Diagnostic Approach in Spinal Infection
8(2)
Diagnostic Approach in Bone Fixation Device-Associated Infection
10(2)
Diagnostic Approach in Native Arthritis and Infections after Anterior Cruciate Ligament Repair (ACL-R)
12(3)
Diagnostic Approach in Periprosthetic Joint Infections (PJI)
15(2)
Key Points
17(1)
References
17(4)
Chapter 3 Unusual Microorganisms in Periprosthetic Joint Infection 21(30)
Camelia Marculescu
Werner Zimmerli
Introduction
21(1)
Gram-Positive Microorganisms
21(5)
Gram-Negative Microorganisms
26(3)
Zoonotic Microorganisms
29(5)
Anaerobic Microorganisms
34(1)
Mycobacteria
35(3)
Other Microorganisms
38(2)
Key Points
40(1)
References
40(11)
Chapter 4 Identification of Pathogens in Bone and Joint Infections by Non-Culture Techniques 51(14)
Maria Eugenia Portillo
Stephane Corvec
Introduction
51(1)
Broad-Range PCR
51(2)
Targeted PCR
53(1)
Multiplex PCR
54(1)
Next-Generation Sequencing Approach
55(3)
Mass Spectrometry-Based Methods
58(3)
Key Points
61(1)
References
61(4)
Chapter 5 Bacteriophages for Treatment of Biofilm Infections 65(16)
Mercedes Gonzalez-Moreno
Paula Morovic
Tamta Tkhilaishvili
Andrej Trampuz
History of Bacteriophage Use in Human Infections
65(1)
Principles of Bacteriophage Therapy
66(3)
Activity of Bacteriophages against Bacterial Biofilms and Persisters
69(2)
Bacteriophage Susceptibility Testing: the Phagogram
71(1)
Experimental and Clinical Evidence with Bacteriophage Treatment
72(2)
Local Delivery and Systemic Bacteriophage Application
74(2)
Outlook and Future Perspectives
76(1)
Key Points
77(1)
References
78(3)
Chapter 6 Pharmacokinetics and Pharmacodynamics of Antibiotics in Bone 81(18)
Cornelia B. Landersdorfer
Jurgen B. Bulitta
Roger L. Nation
Fritz Sorgel
Pharmacokinetics
81(1)
Bone Sample Preparation and Analysis
82(1)
Pharmacokinetic Sampling and Data Analysis
83(1)
Penetration of Antibiotics into Bone
84(9)
Pharmacodynamics and Monte Carlo Simulations
93(2)
Conclusions
95(1)
Key Points
96(1)
References
96(3)
Chapter 7 Preclinical Models of Infection in Bone and Joint Surgery 99(18)
Caroline Constant
Lorenzo Calabro
Willem-Jan Metsemakers
R. Geoff Richards
T. Fintan Moriarty
Introduction
99(1)
Influence of Species in Preclinical Models of Bone and Joint Infection
100(3)
Overview of Animal Models
103(1)
Direct Inoculation with Minimal Trauma
103(5)
Animal Models of Bone and Joint Infection Incorporating Trauma
108(1)
Hematogenous Models
108(1)
Future Directions
109(1)
Conclusions
110(1)
Key Points
110(1)
References
110(7)
Chapter 8 Native Joint Arthritis in Children 117(22)
Pablo Yagupsky
Introduction
117(1)
Epidemiology
117(1)
Microbiology
118(4)
Pathogenesis
122(1)
Clinical Presentation
123(2)
Laboratory Investigation
125(2)
Imaging Studies
127(1)
Differential Diagnosis
128(1)
Treatment
128(5)
Prognosis
133(1)
Key Points
134(1)
References
134(5)
Chapter 9 Native Joint Arthritis in Adults 139(12)
Florian B. Imhoff
David E. Bauer
Ilker Uckay
Introduction
139(1)
Risk Factors
139(1)
Pathogenesis, Epidemiology, and Microbiology
140(1)
Diagnosis
141(3)
Treatment
144(3)
Outcome
147(1)
Key Points
148(1)
Acknowledgments
148(1)
References
148(3)
Chapter 10 Septic Arthritis of Axial Joints 151(20)
Werner Zimmerli
Septic Arthritis of the Sternoclavicular Joint
151(6)
Key Points
157(1)
Septic Arthritis of the Symphysis Pubis
157(4)
Key Points
161(1)
Septic Arthritis of the Sacroiliac Joint
161(4)
Key Points
165(1)
References
165(6)
Chapter 11 Periprosthetic Joint Infection: General Aspects 171(16)
Werner Zimmerli
Introduction
171(1)
Definition
172(1)
Classification
172(1)
Pathogenesis
172(4)
Laboratory Investigation
176(2)
Therapeutic Management
178(1)
Prophylaxis
179(1)
Errors in the Management of PJI
180(1)
Key Points
180(1)
References
181(6)
Chapter 12 Periprosthetic Joint Infection after Total Hip and Knee Arthroplasty 187(26)
Werner Zimmerli
Rihard Trebse
Martin Clauss
Introduction
187(1)
Risk Factors
188(1)
Microbiology
188(1)
Clinical Features
189(1)
Laboratory Investigation
190(1)
Imaging Procedures
191(1)
Management
192(10)
Instructive Cases
202(4)
References
206(7)
Chapter 13 Periprosthetic Joint Infection after Shoulder Arthroplasty 213(18)
Parham Sendi
Andreas Marc Muller
Beat K. Moor
Matthias A. Zumstein
Introduction
213(1)
Risk Factors
213(2)
Microbiology
215(1)
Pathogenesis
216(1)
Clinical Features
217(1)
Laboratory Investigation
218(2)
Imaging Procedures
220(1)
Management
220(4)
Instructive Cases
224(2)
References
226(5)
Chapter 14 Periprosthetic Joint Infection after Elbow Arthroplasty 231(20)
Yvonne Achermann
Michael C. Glanzmann
Christoph Spormann
Introduction
231(1)
Microbiology
232(1)
Clinical Features
232(2)
Diagnostic Procedures
234(3)
Management
237(5)
Instructive Cases
242(3)
References
245(6)
Chapter 15 Periprosthetic Joint Infection after Ankle Arthroplasty 251(14)
Parham Sendi
Bernhard Kessler
Markus Knupp
Introduction
251(1)
Risk Factors
252(2)
Microbiology
254(1)
Clinical Features
254(1)
Laboratory Investigation
255(1)
Imaging Procedures
256(1)
Management
257(3)
Instructive Cases
260(2)
References
262(3)
Chapter 16 Osteomyelitis: Classification 265(8)
Werner Zimmerli
Classification According to Pathogenesis
265(2)
Classification According to the Duration of Infection
267(1)
Classification According to the Localization
268(1)
Classification According to the Presence of an Implant
269(1)
Classification According to Anatomy and Comorbidity
269(1)
References
270(3)
Chapter 17 Osteomyelitis in Children 273(16)
Alexander Aarvold
Priya Sukhtankar
Saul N. Faust
Introduction
273(1)
Epidemiology
273(1)
Pathophysiology
274(1)
Clinical Presentation, Diagnosis, and Microbiology
275(7)
Treatment
282(2)
Complications
284(1)
Key Points
285(1)
References
286(3)
Chapter 18 Acute Osteomyelitis in Adults 289(20)
Werner Zimmerli
Introduction
289(1)
Pathogenesis
289(1)
Epidemiology
290(1)
Microbiology
291(2)
Risk Factors
293(2)
Clinical Features
295(1)
Laboratory Investigation
296(2)
Imaging Procedures
298(2)
Clinical and Imaging Differential Diagnosis
300(1)
Treatment
301(3)
Key Points
304(1)
References
304(5)
Chapter 19 Subacute Osteomyelitis: Tuberculous and Brucellar Vertebral Osteomyelitis 309(16)
Juan D. Colmenero
Pilar Morata
Introduction
309(1)
Epidemiology
309(1)
Clinical Features
310(2)
Laboratory Investigation
312(3)
Imaging Procedures
315(3)
Antimicrobial and Surgical Therapy
318(3)
Key Points
321(1)
References
321(4)
Chapter 20 Chronic Osteomyelitis in Adults 325(12)
Felix W.A. Waibel
Benedikt Jochum
Ilker Uckay
Introduction
325(1)
Pathogenesis
326(1)
Diagnosis
326(2)
Treatment
328(5)
Key Points
333(1)
Acknowledgments
333(1)
References
333(4)
Chapter 21 Diabetic Foot Osteomyelitis 337(16)
Eric Senneville
Olivier Robineau
Introduction
337(1)
Classification
337(2)
Microbiology
339(2)
Risk Factors
341(1)
Clinical Features
342(1)
Inflammatory Parameters
342(1)
Imaging Procedures
343(1)
Treatment
344(3)
Prevention
347(1)
References
348(5)
Chapter 22 Osteomyelitis of the Jaws 353(14)
Werner Zimmerli
Introduction
353(1)
Classification
353(2)
Microbiology
355(1)
Risk Factors
356(1)
Clinical Features
356(3)
Laboratory Investigation
359(1)
Imaging Procedures
360(1)
Management
361(2)
Key Points
363(1)
References
364(3)
Chapter 23 Fracture-Related Infection of the Long Bones 367(20)
Parham Sendi
Mario Morgenstern
Willem-Jan Metsemakers
Martin McNally
Introduction
367(1)
Classification and Risk Factors
368(2)
Microbiology
370(1)
Clinical Features
371(1)
Laboratory Investigation
372(1)
Imaging Procedures
373(1)
Management
373(7)
Instructive Cases
380(3)
References
383(4)
Chapter 24 Implant-Associated Vertebral Osteomyelitis 387(22)
Todd J. Kowalski
Arick P. Sabin
Introduction
387(1)
Classification and Risk Factors
388(1)
Microbiology
389(4)
Clinical Features
393(1)
Diagnostic Procedures
393(2)
Treatment
395(7)
Instructive Cases
402(2)
References
404(5)
Chapter 25 Postoperative Sternal Osteomyelitis 409(20)
Parham Sendi
Mihai Constantinescu
Lars Englberger
Introduction
409(1)
Risk Factors
410(4)
Microbiology
414(1)
Clinical Features
414(1)
Laboratory Investigation
415(2)
Imaging Procedures
417(1)
Management
417(5)
Instructive Cases
422(3)
References
425(4)
Index 429
Werner Zimmerli is Professor Emeritus in Internal Medicine and Infectious Diseases and Consultant for Orthopedic Infections at the Kantonsspital Baselland/Liestal. His primary research focus is on implant-associated infections. He is also the co-publisher of an algorithm on the surgical management of periprosthetic joint infection.
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