"This book, Clinical Biochemistry and Drug Development: From Fundamentals to Output, focuses on clinical biochemistry fundamentals, cell culture techniques, and drug discovery and development concepts. It deals with three different fields of clinical research: cell culture, clinical biochemistry, and drug discovery and development. The book introduces cell animal and bacterial culture techniques and their potential uses as well as cell culture techniques. The biochemistry aspect of the book covers the principles of clinical biochemistry and biochemical analysis, biochemical aids to clinical diagnosis, measurement, and quality control. The book also presents important concepts in cell membrane receptor signal transduction pathways as drug targets. The drug development focus of the book discusses the fundamentals of human disease and drug discovery. Various in silico, in vitro, and in vivo approaches for drug discovery are examined, along with a discussion on drug delivery carriers and clinical trials. Overall, the volume provides an overview of the journey from clinical fundamentals to clinical output. The book aims to provide an understanding for the students of health science and life sciences. This book involves the fundamentals of clinical biochemistry and use of cell culture techniques. Furthermore the book will discuss the fundamentals of drug discovery and development. Over the entire boo"--
This book, Clinical Biochemistry and Drug Development: From Fundamentals to Output, focuses on clinical biochemistry fundamentals, cell culture techniques, and drug discovery and development concepts. It deals with three different fields of clinical research: cell culture, clinical biochemistry, and drug discovery and development. The book introduces cell animal and bacterial culture techniques and their potential uses as well as cell culture techniques. The biochemistry aspect of the book covers the principles of clinical biochemistry and biochemical analysis, biochemical aids to clinical diagnosis, measurement, and quality control. The book also presents important concepts in cell membrane receptor signal transduction pathways as drug targets. The drug development focus of the book discusses the fundamentals of human disease and drug discovery.
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ix | |
| Abbreviations |
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xi | |
| Preface |
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xvii | |
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1 An Introduction to Cell Culture |
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4 Potential Use of Cell Cultures |
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5 Principles of Clinical Biochemistry and Biochemical Analysis |
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6 Biochemical Aids to Clinical Diagnosis |
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7 Clinical Measurements and Quality Control |
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M. S. Sandeep Vedanarayana |
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9 Mechanisms of Signal Transduction |
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10 Human Disease Drug Therapy and Drug Discovery |
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11 Drug Development: In Silico, In Vivo, and System Biology Approach |
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12 Drug Development: Drug Delivery Carriers and Clinical Trial |
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13 Role of Micro RNA in Prostate Cancer Therapy |
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14 Pathogenesis, Molecular Mechanisms of Progression, and Therapeutic Targets of Liver Fibrosis: An Update |
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15 Prostate Cancer: Molecular Aspects, Biomarkers, and Chemo-Preventive Agents |
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16 Overview of Tuberculosis Biomarkers: An Update |
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219 | (14) |
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| Index |
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233 | |
Shashank Kumar, PhD, is an Assistant Professor in the Department of Biochemistry and Microbial Sciences at the Central University of Punjab, India. He previously worked as a postdoctoral fellow at the Department of Biochemistry at King Georges Medical University, India. Dr. Kumar has edited several books, including Concepts in Cell Signaling; Secondary Metabolites and Functional Food Components; Carbohydrate Metabolism Theory and Practical Approach; Phytochemistry: An in silico and in vitro Update; among others. Dr. Kumar has published more than 30 scientific papers, reviews, and editorial articles in various national and international journals. He has expertise in the areas of free radical biology, cancer biology, cell culture techniques, characterization of plant products, xenobiotic metabolism, and microbiology. He has presented his research findings at more than 25 national and international conferences and has attended many workshops at many major universities and medical colleges throughout India. Dr. Kumar is an editorial board member and reviewer for about 25 international journals. He is a lifetime member of the Italo-Latin American Society of Ethnomedicine and the Indian Sciences Congress Association and is also a member of Publication Integrity & Ethics, London, UK. Dr. Kumar received his BSc, MSc, and PhD degrees in biochemistry from the Department of Biochemistry, University of Allahabad, India.
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