This book, Clinical Biochemistry and Drug Development: From Fundamentals to Output, focuses on clinical biochemistry fundamentals, cell culture techniques, and drug discovery and development concepts. It deals with three different fields of clinical research: cell culture, clinical biochemistry, and drug discovery and development.
This new volume focuses on clinical biochemistry fundamentals, cell culture techniques, and drug discovery and development concepts. It deals with three different fields of clinical research: cell culture, clinical biochemistry, and drug discovery and development.
The book introduces cell animal and bacterial culture techniques and their potential uses as well as cell culture techniques. The biochemistry aspect of the book covers the principles of clinical biochemistry and biochemical analysis, biochemical aids to clinical diagnosis, measurement, and quality control. The book also presents important concepts in cell membrane receptor signal transduction pathways as drug targets.
The drug development focus of the book discusses the fundamentals of human disease and drug discovery. Various in silico, in vitro, and in vivo approaches for drug discovery are examined, along with a discussion on drug delivery carriers and clinical trials. Overall, the volume provides an overview of the journey from clinical fundamentals to clinical output.
1. An Introduction to Cell Culture
2. Animal Cell Culture
3. Bacterial
Cell Culture
4. Potential Use of Cell Cultures
5. Principles of Clinical
Biochemistry and Biochemical Analysis
6. Biochemical Aids to Clinical
Diagnosis
7. Clinical Measurements and Quality Control
8. Cell Membrane
Receptor
9. Mechanisms of Signal Transduction
10. Human Disease Drug
Therapy and Drug Discovery
11. Drug Development: In Silico, In Vivo and
System Biology Approach
12. Drug Development: Drug Delivery Carriers and
Clinical Trial
13. Role of Micro RNA in Prostate Cancer Therapy
14.
Pathogenesis, Molecular Mechanisms of Progression, and Therapeutic Targets of
Liver Fibrosis: An Update
15. Prostate Cancer: Molecular Aspects,
Biomarkers, and Chemo-Preventive Agents
16. Overview of Tuberculosis
Biomarkers: An Update
Shashank Kumar, PhD, is an Assistant Professor in the Department of Biochemistry and Microbial Sciences at the Central University of Punjab, India. He previously worked as a postdoctoral fellow at the Department of Biochemistry at King Georges Medical University, India. Dr. Kumar has edited several books, including Concepts in Cell Signaling; Secondary Metabolites and Functional Food Components; Carbohydrate Metabolism Theory and Practical Approach; Phytochemistry: An in silico and in vitro Update; among others. Dr. Kumar has published more than 30 scientific papers, reviews, and editorial articles in various national and international journals. He has expertise in the areas of free radical biology, cancer biology, cell culture techniques, characterization of plant products, xenobiotic metabolism, and microbiology. He has presented his research findings at more than 25 national and international conferences and has attended many workshops at many major universities and medical colleges throughout India. Dr. Kumar is an editorial board member and reviewer for about 25 international journals. He is a lifetime member of the Italo-Latin American Society of Ethnomedicine and the Indian Sciences Congress Association and is also a member of Publication Integrity & Ethics, London, UK. Dr. Kumar received his BSc, MSc, and PhD degrees in biochemistry from the Department of Biochemistry, University of Allahabad, India.
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