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E-raamat: Cyclic Nucleotide Signaling [Taylor & Francis e-raamat]

Edited by (University of Texas Health Science Center, Houston, USA)
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Cyclic Nucleotide SignalingSuurem pilt
Teised raamatud teemal:
Taylor & Francis e-raamatudRohkem infot Taylor & Francis e-raamatute kohta
Raamatu kodulehekülg: https://www.taylorfrancis.com/books/9780429161926
Showcasing the recent progresses of the field, Cyclic Nucleotide Signaling covers the major tools and methodologies used in various areas of research. The majority of the chapters are protocol oriented, with the goal of providing clear directions for laboratory use. Students and investigators new to the field will find this book particularly informative, as will scientists already actively researching nucleotide signaling.
Compartmentalization of cyclic nucleotide signaling. Analysis of
EPAC-mediated cAMP functions in cell communication. Cyclic nucleotide analogs
as pharmacological tools for studying signaling pathways. Discovery of small
molecule EPAC specific modulators. Adenylyl cyclase and A kinase-anchoring
proteins in cardiovascular physiology and pathology. Cyclic nucleotide
recognition and selectivity. Real-time intracellular imaging of cGMP.
Dissecting cyclic nucleotide signalosomes by chemical proteomics. Cyclic
nucleotide analogs as chemical tools for interaction analyses. cAMP signaling
in pancreatic ß cells. Quantitative high throughput cAMP assay for G-protein
coupled receptors. Quantitative proteomics analysis of the cAMP signaling
pathway. Network analysis of cyclic nucleotide signaling. Evolution and
functional diversity of cyclic nucleotide binding domains. X-ray
crystallographic analysis of cyclic nucleotide activated protein kinases.
Dissect physiological functions of PKA isoforms using genetically modified
mouse models. Assessing cyclic nucleotide binding domain allostery by NMR
analysis. Fluorescence resonance energy transfer (FRET) imaging of cyclic
nucleotide in live cells. Structural and functional analyses of exchange
protein directly activated by cAMP. Structural analysis of PKA: strategies
for therapeutic intervention. Monitoring cyclic nucleotide signaling using
genetically encoded fluorescent reporters.
Cheng, Xiaodong
Püsilink: https://www.kriso.ee/db/9780429161926_pe.html
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