| List of Contributors |
|
xv | |
| Symbols and Abbreviations |
|
xvii | |
| 1 Scientific principles in clinical toxicology |
|
1 | (30) |
|
Epidemiology of poisoning |
|
|
2 | (2) |
|
Basic mechanisms of poisoning |
|
|
4 | (4) |
|
Basic mechanisms of mutagenicity and carcinogenicity |
|
|
8 | (2) |
|
Drug handling in the poisoned patient—toxicokinetics |
|
|
10 | (2) |
|
Poisons information services |
|
|
12 | (2) |
|
|
|
14 | (2) |
|
Principles of surveillance of non-pharmaceutical poisoning (toxicovigilance) |
|
|
16 | (4) |
|
|
|
20 | (2) |
|
Study assessment and interpretation |
|
|
22 | (2) |
|
Classification of psychiatric disorders and principles of treatment relevant to poisoning |
|
|
24 | (4) |
|
Risk assessment and principles of occupational exposure assessment |
|
|
28 | (3) |
| 2 General management of the poisoned patient |
|
31 | (32) |
|
Assessment and general management |
|
|
32 | (4) |
|
|
|
36 | (4) |
|
Principles of enhanced elimination in the poisoned patient |
|
|
40 | (2) |
|
|
|
42 | (4) |
|
Drug and alcohol withdrawal |
|
|
46 | (2) |
|
Management of the pregnant woman who is poisoned |
|
|
48 | (4) |
|
Psychiatric risk assessment and management of the patient with self-harm |
|
|
52 | (4) |
|
Management of vulnerable, violent, and disturbed patients |
|
|
56 | (3) |
|
UK health law and competency and its application to the poisoned patient |
|
|
59 | (4) |
| 3 Common complications of poisoning |
|
63 | (32) |
|
|
|
64 | (4) |
|
Respiratory tract management in poisoning |
|
|
68 | (2) |
|
|
|
70 | (3) |
|
|
|
73 | (2) |
|
Acid—base and electrolyte disturbances in the poisoned patient |
|
|
75 | (2) |
|
Rhabdomyolysis and compartment syndrome |
|
|
77 | (2) |
|
|
|
79 | (2) |
|
|
|
81 | (2) |
|
The anticholinergic syndrome |
|
|
83 | (2) |
|
|
|
85 | (2) |
|
|
|
87 | (2) |
|
Delirium (acute confusional state) |
|
|
89 | (2) |
|
|
|
91 | (2) |
|
|
|
93 | (2) |
| 4 CNS drugs |
|
95 | (20) |
|
|
|
96 | (4) |
|
|
|
100 | (4) |
|
|
|
104 | (2) |
|
|
|
106 | (2) |
|
|
|
108 | (2) |
|
|
|
110 | (2) |
|
|
|
112 | (3) |
| 5 Analgesics |
|
115 | (16) |
|
|
|
116 | (6) |
|
Non-steroidal anti-inflammatory drugs |
|
|
122 | (2) |
|
|
|
124 | (4) |
|
|
|
128 | (3) |
| 6 Cardiovascular acting agents |
|
131 | (18) |
|
Beta-adrenoceptor antagonists |
|
|
132 | (2) |
|
|
|
134 | (2) |
|
ACE inhibitors and angiotensin receptor antagonists |
|
|
136 | (2) |
|
|
|
138 | (2) |
|
|
|
140 | (2) |
|
|
|
142 | (4) |
|
|
|
146 | (3) |
| 7 Other common pharmaceutical toxins |
|
149 | (30) |
|
Antibiotics and antituberculous drugs |
|
|
150 | (2) |
|
|
|
152 | (2) |
|
|
|
154 | (4) |
|
|
|
158 | (2) |
|
|
|
160 | (2) |
|
|
|
162 | (2) |
|
|
|
164 | (2) |
|
|
|
166 | (2) |
|
Methotrexate and other chemotherapeutic agents |
|
|
168 | (4) |
|
|
|
172 | (2) |
|
Thyroxine and tri-iodothyronine |
|
|
174 | (2) |
|
|
|
176 | (3) |
| 8 Drugs of abuse |
|
179 | (26) |
|
Introduction to problems in the drug user |
|
|
180 | (2) |
|
Amfetamines and related compounds |
|
|
182 | (2) |
|
|
|
184 | (2) |
|
|
|
186 | (2) |
|
Gamma-hydroxybutyrate and related compounds |
|
|
188 | (2) |
|
Ketamine and related compounds |
|
|
190 | (2) |
|
|
|
192 | (2) |
|
|
|
194 | (2) |
|
|
|
196 | (2) |
|
|
|
198 | (2) |
|
|
|
200 | (2) |
|
Body packers and stuffers |
|
|
202 | (3) |
| 9 Common chemical poisonings |
|
205 | (60) |
|
|
|
206 | (2) |
|
|
|
208 | (4) |
|
|
|
212 | (2) |
|
|
|
214 | (2) |
|
|
|
216 | (2) |
|
|
|
218 | (1) |
|
|
|
219 | (2) |
|
|
|
221 | (4) |
|
|
|
225 | (2) |
|
Complex glycols (glycol ethers) |
|
|
227 | (2) |
|
|
|
229 | (3) |
|
Dioxins and polychlorinated biphenyls |
|
|
232 | (2) |
|
|
|
234 | (2) |
|
|
|
236 | (3) |
|
|
|
239 | (1) |
|
Ethylene and diethylene glycols |
|
|
240 | (2) |
|
Fluoroacetate (sodium fluoroacetate) |
|
|
242 | (3) |
|
Formaldehyde and metaldehyde |
|
|
245 | (2) |
|
|
|
247 | (2) |
|
|
|
249 | (1) |
|
|
|
250 | (2) |
|
|
|
252 | (2) |
|
Naphthalene and paradichlorobenzene |
|
|
254 | (1) |
|
Nitrogen and nitrogen oxides, and smoke inhalation |
|
|
255 | (2) |
|
Phenol and related compounds |
|
|
257 | (3) |
|
|
|
260 | (1) |
|
|
|
261 | (1) |
|
|
|
262 | (2) |
|
|
|
264 | (1) |
| 10 Poisoning due to metals, and their salts |
|
265 | (24) |
|
|
|
266 | (1) |
|
|
|
267 | (4) |
|
|
|
271 | (1) |
|
|
|
272 | (2) |
|
|
|
274 | (1) |
|
Fluoride (sodium fluoride) |
|
|
275 | (1) |
|
|
|
276 | (2) |
|
|
|
278 | (1) |
|
Mercury and mercury salts |
|
|
279 | (4) |
|
|
|
283 | (1) |
|
|
|
284 | (2) |
|
|
|
286 | (3) |
| 11 Household products |
|
289 | (8) |
|
|
|
290 | (2) |
|
Antiseptics and disinfectants |
|
|
292 | (2) |
|
Non-toxic household products |
|
|
294 | (3) |
| 12 Pesticides, herbicides, and rodenticides |
|
297 | (18) |
|
Organophosphorus insecticides |
|
|
298 | (3) |
|
|
|
301 | (2) |
|
Other insecticides: pyrethroids, nicotine, and neonicotinoids |
|
|
303 | (2) |
|
|
|
305 | (2) |
|
|
|
307 | (2) |
|
|
|
309 | (2) |
|
|
|
311 | (2) |
|
Aluminium phosphide and phosphine |
|
|
313 | (2) |
| 13 Poisoning due to fungi, plants, and animals |
|
315 | (20) |
|
|
|
316 | (4) |
|
|
|
320 | (4) |
|
Venomous animals—spiders and scorpions |
|
|
324 | (4) |
|
|
|
328 | (4) |
|
|
|
332 | (3) |
| 14 Chemical warfare agents |
|
335 | (22) |
|
|
|
336 | (2) |
|
Outline of chemical incident management |
|
|
338 | (4) |
|
|
|
342 | (3) |
|
|
|
345 | (2) |
|
|
|
347 | (1) |
|
|
|
348 | (2) |
|
|
|
350 | (2) |
|
|
|
352 | (3) |
|
Centrally acting incapacitating agents |
|
|
355 | (2) |
| 15 Principles of radiation toxicology |
|
357 | (24) |
|
Outline to radiation biology as applied to poisoning |
|
|
358 | (3) |
|
Biological dosimetry for the clinician |
|
|
361 | (2) |
|
|
|
363 | (4) |
|
|
|
367 | (4) |
|
|
|
371 | (4) |
|
|
|
375 | (1) |
|
Triage, monitoring, treatment for management of the public in the event of a radiation release |
|
|
376 | (2) |
|
Treatment of internal contamination with radionuclides |
|
|
378 | (3) |
| 16 Occupational and industrial aspects of toxicology assessment |
|
381 | (12) |
|
Principles of industrial hygiene and toxic hazards in the workplace |
|
|
382 | (6) |
|
Medical surveillance in the workplace |
|
|
388 | (2) |
|
Principles of air and water safety standards and their regulations |
|
|
390 | (3) |
| Index |
|
393 | |
Rohkem infot Oxford Medicine Online e-raamatute kohta