| List of Contributors |
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xv | |
| Symbols and Abbreviations |
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xvii | |
| 1 Scientific principles in clinical toxicology |
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1 | (30) |
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Epidemiology of poisoning |
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2 | (2) |
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Basic mechanisms of poisoning |
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4 | (4) |
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Basic mechanisms of mutagenicity and carcinogenicity |
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8 | (2) |
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Drug handling in the poisoned patient—toxicokinetics |
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10 | (2) |
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Poisons information services |
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12 | (2) |
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14 | (2) |
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Principles of surveillance of non-pharmaceutical poisoning (toxicovigilance) |
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16 | (4) |
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20 | (2) |
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Study assessment and interpretation |
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22 | (2) |
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Classification of psychiatric disorders and principles of treatment relevant to poisoning |
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24 | (4) |
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Risk assessment and principles of occupational exposure assessment |
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28 | (3) |
| 2 General management of the poisoned patient |
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31 | (32) |
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Assessment and general management |
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32 | (4) |
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36 | (4) |
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Principles of enhanced elimination in the poisoned patient |
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40 | (2) |
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42 | (4) |
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Drug and alcohol withdrawal |
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46 | (2) |
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Management of the pregnant woman who is poisoned |
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48 | (4) |
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Psychiatric risk assessment and management of the patient with self-harm |
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52 | (4) |
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Management of vulnerable, violent, and disturbed patients |
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56 | (3) |
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UK health law and competency and its application to the poisoned patient |
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59 | (4) |
| 3 Common complications of poisoning |
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63 | (32) |
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64 | (4) |
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Respiratory tract management in poisoning |
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68 | (2) |
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70 | (3) |
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73 | (2) |
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Acid—base and electrolyte disturbances in the poisoned patient |
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75 | (2) |
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Rhabdomyolysis and compartment syndrome |
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77 | (2) |
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79 | (2) |
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81 | (2) |
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The anticholinergic syndrome |
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83 | (2) |
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85 | (2) |
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87 | (2) |
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Delirium (acute confusional state) |
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89 | (2) |
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91 | (2) |
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93 | (2) |
| 4 CNS drugs |
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95 | (20) |
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96 | (4) |
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100 | (4) |
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104 | (2) |
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106 | (2) |
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108 | (2) |
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110 | (2) |
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112 | (3) |
| 5 Analgesics |
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115 | (16) |
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116 | (6) |
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Non-steroidal anti-inflammatory drugs |
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122 | (2) |
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124 | (4) |
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128 | (3) |
| 6 Cardiovascular acting agents |
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131 | (18) |
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Beta-adrenoceptor antagonists |
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132 | (2) |
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134 | (2) |
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ACE inhibitors and angiotensin receptor antagonists |
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136 | (2) |
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138 | (2) |
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140 | (2) |
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142 | (4) |
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146 | (3) |
| 7 Other common pharmaceutical toxins |
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149 | (30) |
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Antibiotics and antituberculous drugs |
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150 | (2) |
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152 | (2) |
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154 | (4) |
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158 | (2) |
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160 | (2) |
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162 | (2) |
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164 | (2) |
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166 | (2) |
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Methotrexate and other chemotherapeutic agents |
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168 | (4) |
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172 | (2) |
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Thyroxine and tri-iodothyronine |
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174 | (2) |
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176 | (3) |
| 8 Drugs of abuse |
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179 | (26) |
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Introduction to problems in the drug user |
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180 | (2) |
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Amfetamines and related compounds |
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182 | (2) |
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184 | (2) |
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186 | (2) |
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Gamma-hydroxybutyrate and related compounds |
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188 | (2) |
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Ketamine and related compounds |
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190 | (2) |
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192 | (2) |
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194 | (2) |
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196 | (2) |
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198 | (2) |
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200 | (2) |
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Body packers and stuffers |
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202 | (3) |
| 9 Common chemical poisonings |
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205 | (60) |
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206 | (2) |
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208 | (4) |
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212 | (2) |
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214 | (2) |
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216 | (2) |
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218 | (1) |
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219 | (2) |
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221 | (4) |
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225 | (2) |
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Complex glycols (glycol ethers) |
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227 | (2) |
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229 | (3) |
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Dioxins and polychlorinated biphenyls |
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232 | (2) |
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234 | (2) |
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236 | (3) |
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239 | (1) |
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Ethylene and diethylene glycols |
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240 | (2) |
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Fluoroacetate (sodium fluoroacetate) |
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242 | (3) |
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Formaldehyde and metaldehyde |
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245 | (2) |
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247 | (2) |
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249 | (1) |
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250 | (2) |
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252 | (2) |
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Naphthalene and paradichlorobenzene |
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254 | (1) |
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Nitrogen and nitrogen oxides, and smoke inhalation |
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255 | (2) |
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Phenol and related compounds |
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257 | (3) |
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260 | (1) |
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261 | (1) |
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262 | (2) |
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264 | (1) |
| 10 Poisoning due to metals, and their salts |
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265 | (24) |
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266 | (1) |
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267 | (4) |
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271 | (1) |
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272 | (2) |
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274 | (1) |
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Fluoride (sodium fluoride) |
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275 | (1) |
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276 | (2) |
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278 | (1) |
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Mercury and mercury salts |
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279 | (4) |
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283 | (1) |
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284 | (2) |
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286 | (3) |
| 11 Household products |
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289 | (8) |
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290 | (2) |
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Antiseptics and disinfectants |
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292 | (2) |
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Non-toxic household products |
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294 | (3) |
| 12 Pesticides, herbicides, and rodenticides |
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297 | (18) |
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Organophosphorus insecticides |
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298 | (3) |
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301 | (2) |
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Other insecticides: pyrethroids, nicotine, and neonicotinoids |
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303 | (2) |
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305 | (2) |
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307 | (2) |
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309 | (2) |
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311 | (2) |
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Aluminium phosphide and phosphine |
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313 | (2) |
| 13 Poisoning due to fungi, plants, and animals |
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315 | (20) |
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316 | (4) |
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320 | (4) |
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Venomous animals—spiders and scorpions |
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324 | (4) |
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328 | (4) |
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332 | (3) |
| 14 Chemical warfare agents |
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335 | (22) |
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336 | (2) |
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Outline of chemical incident management |
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338 | (4) |
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342 | (3) |
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345 | (2) |
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347 | (1) |
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348 | (2) |
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350 | (2) |
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352 | (3) |
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Centrally acting incapacitating agents |
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355 | (2) |
| 15 Principles of radiation toxicology |
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357 | (24) |
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Outline to radiation biology as applied to poisoning |
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358 | (3) |
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Biological dosimetry for the clinician |
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361 | (2) |
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363 | (4) |
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367 | (4) |
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371 | (4) |
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375 | (1) |
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Triage, monitoring, treatment for management of the public in the event of a radiation release |
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376 | (2) |
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Treatment of internal contamination with radionuclides |
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378 | (3) |
| 16 Occupational and industrial aspects of toxicology assessment |
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381 | (12) |
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Principles of industrial hygiene and toxic hazards in the workplace |
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382 | (6) |
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Medical surveillance in the workplace |
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388 | (2) |
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Principles of air and water safety standards and their regulations |
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390 | (3) |
| Index |
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393 | |
Lisainfo e-raamatute kohta