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E-raamat: Arthritis: Pathophysiology, Prevention, and Therapeutics [Taylor & Francis e-raamat]

Edited by , Edited by (University of Houston College of Pharmacy, Houston, TX), Edited by (Researcher at Faculty of Pharma-Science, Laboratory of Drug and Gene Delivery Research, Teikyo University, Tokyo, Japan)
  • Formaat: 608 pages
  • Ilmumisaeg: 15-Oct-2019
  • Kirjastus: CRC Press
  • ISBN-13: 9780429147135
  • Taylor & Francis e-raamat
  • Hind: 281,59 €*
  • * hind, mis tagab piiramatu üheaegsete kasutajate arvuga ligipääsu piiramatuks ajaks
  • Tavahind: 402,26 €
  • Säästad 30%
  • Formaat: 608 pages
  • Ilmumisaeg: 15-Oct-2019
  • Kirjastus: CRC Press
  • ISBN-13: 9780429147135

A debilitating disease of pain, inflammation, and loss of mobility and quality of life, arthritis takes victims of all ages, from young children to seniors. Usually chronic, the broad term arthritis refers to nearly 100 distinct manifestations, each with their own etiology, pathophysiology, and treatment. With medical research getting so much attention, it is no wonder there have been recent leaps in the investigation into arthritis treatment. It is important to have a high quality, trusted compendium to capture the breadth and depth of new information in the field.



Covering cutting-edge information on arthritic diseases and their treatment, Arthritis: Pathophysiology, Prevention, and Therapeutics details the intricacies of arthritis and inflammatory responses, their consequences, their economic burden, and their impact on society. Offering a mechanistic approach to pathophysiology and treatment, the book begins with an overview of rheumatoid arthritis, osteoarthritis, and psoriatic arthritis.





Section Two highlights the consequences of arthritis and the link between arthritis and obesity, diabetes, and cardiovascular disease, as well as other related disabilities. The third section focuses on antiarthritic drugs, including an overview and update on antiarthritic drug development by Dr. Micheal G. Lyon from Stanford University School of Medicine, and a chapter on nonsteroidal anti-inflammatory drugs. Other chapters cover biologics in arthritis treatment, topical applications, and the use of hyaluronan and hyaluronic acid in osteoarthritis and rheumatoid arthritis.





Sections Four and Five are devoted to natural therapeutic and orthopedic interventions such as glucosamine and chondroitin, MSM, capsaicin, shark cartilage, and fish oil, while Section Six discusses nonpharmacological approaches including physical exercise and acupuncture. The final section provides a commentary on the correlation between a

Preface xiii
Editors xv
Contributors xvii
SECTION I Overview and Pathophysiology
Chapter 1 An Overview on Rheumatologic Disorders
3(20)
S. Kumar
Rajiva Gupta
Chapter 2 Pathogenesis of Osteoarthritis
23(16)
Allen P. Anandarajah
Chapter 3 Biomarkers in Osteoarthritis
39(16)
Muneaki Ishijima
Hisashi Kurosawa
Haruka Kaneko
Kazuo Kaneko
Chapter 4 Rheumatoid Arthritis: Disease Pathophysiology
55(20)
Ankit Saxena
Smriti K. Raychaudhuri
Siba P. Raychaudhuri
Chapter 5 Osteoclasts and Interleukin-17-Producing Helper T Cells in Rheumatoid Arthritis
75(16)
Kazuo Okamoto
Hiroshi Takayanagi
Chapter 6 WNT/bT-Catenin Signaling Modulating Osteoarthritis
91(12)
Maripat Corr
Chapter 7 Psoriatic Arthritis: Epidemiology, Risk Factors, and Quality of Life
103(12)
Arathi R. Setty
SECTION II Consequences
Chapter 8 Arthritis, Obesity, Increased Cardiovascular Risk, and Disability
115(10)
Shampa Chatterjee
SECTION III Antiarthritic Drugs
Chapter 9 An Overview: Use of Traditional Antiarthritic Drugs and Update on Drug Development
125(14)
Gabriela Schmajuk
Michael G. Lyon
Chapter 10 Nonsteroidal Anti-Inflammatory Drugs
139(8)
Anand Lal
Seeta Sharma
Chapter 11 Biologics: Target-Specific Treatment of Systemic and Cutaneous Autoimmune Diseases
147(18)
Siba P. Raychaudhuri
Smriti K. Raychaudhuri
Chapter 12 Topical Applications for Pain and Arthritic Diseases
165(18)
Norifumi Tanida
Kotaro Maekawa
Masaru Nakanishi
Chapter 13 Hyaluronic Acid and Arthritis: A Review
183(16)
Michele Abate
Chapter 14 Hyaluronan for the Treatment of Osteoarthritis and Rheumatoid Arthritis
199(20)
Toshiaki Nakano
Yasufumi Takahashi
SECTION IV Natural Therapeutic Interventions
Chapter 15 Immunomodulatory Activities of Japanese Traditional Medicines in Rheumatoid Arthritis
219(12)
Toshiaki Kogure
Chapter 16 An Overview on Natural Therapeutic Interventions
231(6)
Stanley Naguwa
Chapter 17 Potential Health Benefits from Nutrition and Dietary Supplements in the Prevention of Osteoarthritis and Rheumatoid Arthritis
237(8)
Cathy Creger Rosenbaum
Chapter 18 Antiarthritic Potential of Glucosamine and Chondroitin: An Overview
245(10)
Michael W. Orth
Pooi-See Chan
Chapter 19 An Overview on N-Acetylglucosamine and Arthritis
255(6)
Daiki Kubomura
Uzuka Naoaki
Yoshiharu Matahira
Chapter 20 Hexosamine Flux and the Efficacy and Safety of Glucosamine in the Treatment of Osteoarthritis
261(22)
Akhtar Afshan Ali
William Salminen
Julian E. Leakey
Chapter 21 Safety and Efficacy of a Unique Undenatured Type II Collagen in the Treatment of Arthritis
283(12)
Siba P. Raychaudhuri
Ramesh C. Gupta
Hiroyoshi Moriyama
Manashi Bagchi
Francis C. Lau
Debasis Bagchi
Chapter 22 Targeting Inflammatory Pathways by Nutraceuticals for Prevention and Treatment of Arthritis
295(30)
Bokyung Sung
Gautam Sethi
Kwang Seok Ahn
Manoj K. Pandey
Ajaikumar B. Kunnumakkara
Bharat B. Aggarwal
Chapter 23 Boswellia serrata for Arthritis Relief: A Journey from Frankincense to Aflapin and 5-Loxin
325(16)
Alluri Venkata Krishnaraju
Krishanu Sengupta
Siba P. Raychaudhuri
Golakoti Trimurtulu
Chapter 24 Utilization of Marine Products in the Treatment and Prevention of Osteoarthritis
341(8)
Tadakazu Tamai
Ayako Honmura
Hisashi Yoshioka
Tatsuya Konishi
Shisei Kuninaga
Hiroshi Oda
Akinori Sakamoto
Tsuyoshi Okada
Chapter 25 Benefits of Fish Oil for Rheumatoid Arthritis: A Review
349(36)
Christine Dawczynski
Gerhard Jahreis
Chapter 26 Potential Health Benefits of n-3 and -6 Fatty Acids in Selected Plant Seed Oils in Rheumatoid Arthritis
385(18)
Hiroyuki Takeuchi
Hiroyoshi Moriyama
Debasis Bagchi
Siba P. Raychaudhuri
Chapter 27 Antiarthritic Potential of Bromelain from Ananas comosus and Its Combination
403(6)
Dilip Ghosh
Chapter 28 Anti-Inflammatory Properties of Zingiber officinale var. Rubra (Red Ginger Extract)
409(10)
Hiroshi Shimoda
Chapter 29 Benefits of Radix Tripterygium wilfordii for Rheumatoid Arthritis
419(14)
Xiaojuan He
Shaohua Xu
Miao Jiang
Na Lin
Aiping Lu
Chapter 30 Dehydroepiandrosterone (DHEA): A Review of Its Preclinical Use in the Management of Osteoarthritis
433(10)
Kai Huang
Hai-li-Cai
Chun Zhang
Xiao-wen Zhang
Li-dong Wu
Li-feng Shen
Qiao-feng Guo
Chapter 31 Antiarthritic Potential of Green-Lipped Mussel and Other Marine-Based Nutraceuticals
443(8)
Wendy Pearson
Michael I. Lindinger
Chapter 32 Antioxidant, Anti-Inflammatory, and Anticatabolic Potential of Rosmarinic Acid and High-Rosmarinic Acid Mint (Mentha Spicata) in Osteoarthritis
451(12)
Wendy Pearson
Michael I. Lindinger
Chapter 33 Potential Health Benefits of Orally Administered Hyaluronan in Alleviating Knee Joint Pain
463(10)
Tomoyuki Kanemitsu
Akira Asari
Chapter 34 Pycnogenol---A Nutraceutical for Osteoarthritis
473(20)
Om P. Gulati
SECTION V Orthopedic Approach
Chapter 35 Total Knee Arthroplasty for Osteoarthritis
493(10)
Shuichi Matsuda
Hiromasa Miura
Yukihide Iwamoto
SECTION VI Nonpharmacologic Interventions
Chapter 36 Physical Exercise for Osteoarthritis of the Knee: Main Modality of Treatment and Possible Use for Prevention
503(16)
Hisashi Kurosawa
Chapter 37 Acupuncture for the Treatment of Arthritis
519(24)
Hi-Joon Park
Hyangsook Lee
Chapter 38 Rehabilitative Strategies for Arthritis: Physical, Agents, Exercise, and Prosthesis Therapies
543(10)
Nobuyuki Kawate
Mitsumasa Yoda
Naomi Yoshioka
Masazumi Mizuma
Chapter 39 Rehabilitation for Arthritis: Daily Life Guidelines
553(6)
Fumihito Kasai
Masazumi Mizuma
SECTION VII Commentary
Chapter 40 Arthritis, Aging Society, Exercise, Nutrition, and Other Precautionary Measures
559(4)
Siba P. Raychaudhuri
Hiroyoshi Moriyama
Debasis Bagchi
Index 563
Debasis Baghchi, Ph.D., FACN, CNS, MAIChE, works within the Department of Pharmacy Sciences at University of Houston College of Pharmacy.





Hiroyoshi Moriyama is Founder and Owner of MTI, Inc., a research and development company aimed at producing nutraceutical and cosmeceutical ingredients.