Series Preface |
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vii | |
Preface |
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About the Editor |
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xi | |
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xiii | |
Introduction |
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xv | |
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1 Real-Time Tumor Localization |
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1 | (12) |
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1 | (1) |
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1.2 Tumor Localization Systems |
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1 | (5) |
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Electromagnetic Transponder |
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Respiratory Monitoring Devices |
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1.3 Tumor Localization Methods |
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6 | (3) |
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9 | (4) |
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9 | (4) |
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2 Theoretical Aspects of Target Detection and Tracking |
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13 | (8) |
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2.1 The Likelihood Ratio Test |
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13 | (1) |
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14 | (1) |
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2.3 Implications of Detection Theory |
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15 | (1) |
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15 | (1) |
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2.5 Template Selection and Motion Enhancement |
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15 | (1) |
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2.6 Matching Cost Functions |
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16 | (2) |
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Popular Matching Cost Functions |
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Robust Matching Cost Functions |
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2.7 Tracking and Prediction |
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18 | (3) |
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20 | (1) |
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21 | (8) |
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21 | (1) |
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3.2 Historical Development |
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21 | (1) |
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3.3 Planning and Delivering a Gated Treatment |
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22 | (1) |
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3.4 Candidate Patients and Treatment Sites |
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22 | (1) |
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3.5 Candidate Breathing Behaviors and Respiratory Maneuvers |
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22 | (2) |
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Assessing Regularity and Stability of Respiration |
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Feedback-Guided Free Breathing |
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3.6 Simulating and Planning a Gated Treatment |
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24 | (1) |
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3.7 Delivering a Gated Treatment |
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25 | (1) |
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3.8 Gating Quality Assurance and Control |
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26 | (1) |
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Commissioning a Gating System |
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Routine Quality Assurance |
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3.9 Limitations and Future Developments |
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27 | (2) |
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27 | (2) |
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4 The CyberKnife® Image-Guided Radiosurgery System |
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29 | (4) |
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4.1 Adaptation to Nonperiodic Movement |
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29 | (1) |
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4.2 Adaptation to Periodic (Respiratory) Motion |
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30 | (3) |
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31 | (2) |
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5 Fundamentals of Tracking with a Linac Multileaf Collimator |
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33 | (6) |
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33 | (1) |
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5.2 Intrafraction Breathing Motion |
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34 | (1) |
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5.3 The Early Work on Tracking One-Dimensional Motion |
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34 | (1) |
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5.4 The Fatal Flaw of Motion Deconvolution Attempts |
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35 | (1) |
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5.5 Tracking Two-Dimensional Motion |
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35 | (1) |
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5.6 Tracking Delivery Design by Direct Aperture Optimization in 4D |
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35 | (1) |
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36 | (1) |
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36 | (3) |
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36 | (1) |
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37 | (2) |
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6 Couch-Based Target Alignment |
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39 | (8) |
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39 | (1) |
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6.2 Couch Shifts for Patient Alignment |
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39 | (2) |
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6.3 Transient and Low-Frequency Couch-Based Target Alignment |
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41 | (1) |
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6.4 Dynamic Couch-Based Target Motion Compensation |
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41 | (2) |
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43 | (1) |
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6.6 The Future of Couch-Based Motion Correction in Radiation Therapy |
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44 | (3) |
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45 | (2) |
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7 Robotic LINAC Tracking Based on Correlation and Prediction |
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47 | (18) |
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47 | (1) |
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48 | (6) |
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Basic Correlation Methods |
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Advanced Correlation Methods |
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7.3 Prediction of Respiratory and Pulsatory Motion |
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54 | (5) |
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The MULIN Family of Algorithms |
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59 | (1) |
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60 | (5) |
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Fusion of Prediction and Correlation |
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Using Surrogates to Improve Prediction Quality |
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61 | (1) |
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61 | (4) |
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8 Treatment Planning for Motion Adaptation in Radiation Therapy |
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65 | (12) |
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65 | (1) |
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8.2 Treatment Planning in Radiation Therapy |
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65 | (1) |
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8.3 Image Processing in Treatment Planning |
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66 | (3) |
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8.4 Planning for Motion-Compensated Treatment |
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69 | (3) |
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8.5 Intratreatment Motion Adaption during Treatment Planning |
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72 | (5) |
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73 | (4) |
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9 Treatment Planning for Motion Management via DMLC Tracking |
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77 | (16) |
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77 | (1) |
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Dynamic Multileaf Collimator Intensity-Modulated Delivery |
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9.2 DMLC Tracking Leaf-Sequencing Evolution |
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78 | (1) |
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Basic Governing Equations |
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Summary of Algorithm Properties |
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9.3 DMLC Control Algorithms for 1D Moving and Deforming Targets |
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79 | (2) |
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Optimal Solutions Developed for a Rigid Moving Target Based on Data Collected Before Treatment |
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Optimal Solutions Developed for a Moving, Deforming Target with Motion Data Based on Prior Measurements |
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Self-Corrected Delivery: Dose Delivery and Motion Model Errors |
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9.4 DMLC Control Algorithms for 3D Moving Targets |
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81 | (3) |
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Synchronized MLC for Tongue and Groove |
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Synchronized MLC for Targets Moving in 3D |
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Real-Time Synchronized MLC for Targets Moving in 3D |
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9.5 Toward Motion-Optimized IMRT |
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84 | (2) |
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Organs at Risk Sparing: DMLC Control Algorithms with Constant Linear Accelerator Dose Rate |
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Organs at Risk Sparing: DMLC Control Algorithms with Variable Linear Accelerator Dose Rate |
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9.6 Motion Management in VMAT |
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86 | (2) |
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88 | (5) |
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88 | (1) |
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Appendix 9.A Derivation of the Basic Equations for MLC Tracking of Moving Targets |
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88 | (2) |
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Appendix 9.B Interdependence of Delivery Parameters of VMAT |
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90 | (1) |
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90 | (3) |
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10 Real-Time Motion Adaptation in Tomotherapy® Using a Binary MLC |
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93 | (14) |
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93 | (1) |
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10.2 Binary MLC and TomoTherapy® Treatment System |
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93 | (1) |
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10.3 Real-Time Motion Adaptation Strategies |
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94 | (3) |
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Motion-Adaptive Optimization |
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97 | (2) |
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10.5 System Integration and Experiments |
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99 | (2) |
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101 | (2) |
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103 | (4) |
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103 | (4) |
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11 Combination of a LINAC with 1.5 T MRI for Real-Time Image Guided Radiotherapy |
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107 | (8) |
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107 | (1) |
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11.2 Design Magnetic Resonance Linac |
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107 | (1) |
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108 | (1) |
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11.4 Dosimetry and Treatment Planning |
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108 | (3) |
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111 | (4) |
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112 | (3) |
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115 | (14) |
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115 | (1) |
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12.2 Historical Perspective |
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115 | (4) |
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Cobalt and Conformal Therapy |
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Patient and Tumor Positioning |
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IGRT Begins for Radiotherapy: CT "Snapshots" |
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MRI versus CT Imaging for Intrafraction Organ Motion |
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119 | (2) |
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Gamma-Ray IMRT Treatment Plans |
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12.4 Radiotherapy and MRI |
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121 | (8) |
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126 | (3) |
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13 Fault Detection in Image-Based Tracking |
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129 | (6) |
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13.1 The Hokkaido RTRT System |
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129 | (1) |
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13.2 Tracking, Prediction, and Online Monitoring |
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130 | (1) |
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130 | (1) |
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131 | (1) |
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13.5 Theory of Reliable Systems---Hardware |
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131 | (2) |
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13.6 Theory of Reliable Systems---Software |
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133 | (1) |
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13.7 System Verification and Validation |
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134 | (1) |
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134 | (1) |
Index |
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135 | |