Advances in Carbohydrate Chemistry and Biochemistry, Volume 80 highlights new advances in the field, with this new volume presenting interesting chapters on a range of topics, including Vinyl Sulfone-Modified Carbohydrates: Michael Acceptors and 2p Partners for the Synthesis of Functionalized Sugars, Enantiomerically Pure Carbocycles and Heterocycles and a Biographical Memoire for Leslie Hough.
- Features contributions from leading authorities and industry experts who specialize in carbohydrate chemistry, biochemistry and research
- Integrates the industrial, analytical and technological aspects of biochemistry, organic chemistry and instrumentation methodology in the study of carbohydrates
- Informs and updates on all the latest developments in the field
| Contributors |
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vii | |
| Preface |
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ix | |
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1 Combining computational and experimental studies for a better understanding of cellulose and its analogs |
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1 | (14) |
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1 | (2) |
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2 From primitive models to atomistic details |
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3 | (1) |
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3 The limit of experimental determination |
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4 | (2) |
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4 Modeling crystals and prediction of experimental response |
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6 | (4) |
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5 Understanding the underlying interactions and thermodynamics |
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10 | (1) |
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11 | (4) |
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11 | (4) |
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2 Combining computational chemistry and crystallography for a better understanding of the structure of cellulose |
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15 | (80) |
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16 | (3) |
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II Information from crystals of related small molecules |
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19 | (21) |
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40 | (17) |
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IV Detection of new stabilizing interactions in cellulose with atoms-in-molecules Theory |
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57 | (4) |
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V Modeling crystals of cellulose |
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61 | (7) |
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68 | (2) |
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Appendix. Molecular structure drawings for saccharide analogues having β(1 → 4) linkages |
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70 | (25) |
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82 | (1) |
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83 | (12) |
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3 Recent advances on glycosyltransferases involved in the biosynthesis of the proteoglycan linkage region |
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95 | (26) |
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1 Xylosyltransferase-I/II |
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96 | (9) |
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2 β-1,4-Galactosyltransferase 7 |
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105 | (8) |
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113 | (8) |
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114 | (1) |
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114 | (7) |
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4 Strategies in synthesis of heparin/heparan sulfate oligosaccharides: 2000-present |
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121 | (44) |
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123 | (10) |
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133 | (7) |
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III Active-latent glycosylation strategy |
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140 | (5) |
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145 | (3) |
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V Reactivity-based chemoselective glycosylation |
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148 | (2) |
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VI Reactivity-independent, pre-activation-based, chemoselective glycosylation |
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150 | (4) |
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VII Chemoenzymatic synthesis |
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154 | (3) |
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157 | (8) |
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158 | (1) |
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158 | (7) |
| Author Index |
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165 | (14) |
| Subject Index |
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179 | |
Prof. David C. Baker has a broad research and teaching experience in the organic and medicinal chemistry of the carbohydrates, including nucleosides and cell-surface carbohydrates that are documented in over 200 publications, presentations, and patents. He was elected a Fellow of the American Chemical Society where he has been active principally in the Division of Carbohydrate Chemistry.
