This is the first of three volumes in the series All Dimensions of Pathology, providing a comprehensive foundation for understanding disease mechanisms and the biological basis of pathology. The accompanying volumes focus on clinical applications and modern diagnostic techniques, and together the series offers an integrated overview of contemporary pathology.Fundamentals of Pathology introduces the essential principles underlying disease development, beginning with cellular biology, metabolism, genetic and chromosomal abnormalities, embryogenesis, and congenital disorders. Core concepts such as cell injury, cell death, inflammation, immune responses, hemodynamic disturbances, and mechanisms of carcinogenesis are presented in a structured and accessible manner.
The volume further provides concise system-based introductory chapters that establish the morphological and functional framework of major organ systems, bridging basic mechanisms with organ pathology. Designed for medical students, pathology residents, and clinicians seeking a solid conceptual background, this book emphasizes clarity, scientific accuracy, and clinical relevance.
By integrating molecular mechanisms with classical morphology, Fundamentals of Pathology serves as an essential starting point for mastering pathology as both a scientific discipline and a diagnostic practice.
Basis of Diseases-CELL and METABOLISM.- A Brief Overview of DNA and
Chromosomal Disorders.- EMBRYOGENESIS AND CONGENITAL MALFORMATIONS.- A GLANCE
OF METABOLIC DISORDERS CAN BE DIAGNOSED BY HYSTOPATHOLOGICAL EXAMINATION.-
CELL INJURY AND ADAPTATON MECHANSMS.- TYPES OF CELLS DEATH- NECROSS,
APOPTOSS, AND OTHERS.- INFLAMMATION AND REPAIR.- A BRIEF OVERVIEW OF IMMUNE
SYSTEM.- DISORDERS OF IMMUNE SYSTEM.- Pathology of Cardiovascular System and
Hemodynamic Disorders.- Neoplasia and Basis of Carcinogenesis.- THE
DIFFERENCES BETWEEN CANCER CELLS AND NORMAL CELLS.- Angiogenesis, invasion
and metastasis.- BASIC SIGNALING PATHWAYS AND DNA REPAIR MECHANISMS EFFECTIVE
IN CARCINOGENESIS.- Autophagia, Epigenetic, and Other Novel Mechanisms in
Carcinogenesis.- A Brief Overview of Gastrointestinal System.- A Brief
Overview of Hepatopancreatobiliary System.- RESPIRATORY SYSTEM FROM A TO Z.-
ABC of Urinary Tracts and Male Genital System.- ABC OF FEMALE REPRODUCTIVE
SYSTEM.- ABC OF HEMOPOIETIC HEMATOPOIETIC SYSTEM.- ABC OF DERMATOPATHOLOGY.-
ABC of Nervous System v30.
Gulden Diniz is professor of pathology at the Izmir Democracy University. She serves as chief of the Pathology Laboratory of Izmir Buca Seyfi Demirsoy Research Hospital. She graduated from Ege University Faculty of Medicine in 1985. She became a microbiologist and an infectious diseases specialist in 1991 and a pathologist in 1998. In 2011, she completed her basic oncology doctorate education at the Oncology Institute of Dokuz Eylül University. She is interested in muscle and nerve biopsy, transplantation pathology, hematopathology, pediatric pathology, molecular pathology, nephropathology, and dermatopathology. During her education, she has voluntarily studied muscle, nerve, and transplantation pathologies from Professor Carolina Sewry, Professor Sebastian Brandner, and Professor Phillipe Ruiz in 2010 and 2018. She is the author of a Turkish pathology book titled Autobiography of a Live Cell (2009), a Turkish biostatistics book titled Basic Statistics for Dervishes (2015), and a Turkish pathology book series titled Around the Pathology in 380 Days (2017). She is the editor of an international book titled clues for differential diagnosis of neuromuscular disorders (2023). She has also been the editor of the Journal of Izmir Behcet Uz Childrens Hospital since 2011. In addition, she is the author of numerous national and international published articles and book chapters.
