Allergic and Immunologic Diseases: A Practical Guide to the Evaluation, Diagnosis and Management of Allergic and Immunologic Diseases is a valuable resource for researchers in and others in the actual day to day practice of allergy and immunology, with specific information, protocols and algorithms to guide their thinking. It is not meant to be a cookbook, yet it provides practical and usable information and an explanation of why and how we do things the way we do. It also addresses limitations of testing and treatment, and how what we know and what we do not know impacts our choices. It also focuses on scientific based practices, and the known pathophysiology of allergic and immunologic diseases as well as mechanisms of action of various treatment modalities. This book is unique in that it explains the rationale behind everything we do in allergy and immunology and it offers the reader specific information on how to do procedures, order tests and treat allergic and immunologic diseases.
- Contains all useful information on allergic and immunologic diseases, from why we do things the way we do, to how to do them, to interpretation of the results to management of the diseases
- Provides information that can be immediately downloadable for any specific procedure or treatment algorithm for immediate use
- Evaluates the scientific merit and evidence or lack thereof
Section A: Background
1. A history of allergy and immunology
2. The
development of clinical laboratory methods in the diagnosis of human disease
3. Discoveries with significant impact in how we diagnosis and treat diseases
4. Taking an allergy and immunology history and physical
5. Basic genetics
and epigenetics for the immunologist and allergist
6. Immunological studies
utility and limitations
7. Future developments and how they will impact the
practice of medicine
Section B: Diagnosis of allergic diseases
8. Epicutaneous and intradermal
skin testing
9. The interpretation of epicutaneous and intradermal skin
testing for foods
10. The use of in vitro methods to evaluate allergy
11.
Food challenges
12. Testing for the physical urticarias
13. Techniques to
evaluate asthma
14. Drug allergy testing
15. Sinus diseases and
rhinolaryngoscopy
16. Approach to the rash from an allergy/immunology
perspective
17. Patch testing and the evaluation of contact allergy
18. Skin
biopsies and their utility
19. The evaluation of mast cell related disorders
20. The evaluation of a patient with urticaria and angioedema
21. Evaluating
the patient with eosinophilia or eosinophilic disease
22. Unproven and
controversial testing methods in allergy and immunology
Section C: Evaluation of immune function
23. Testing for primary
immunodeficiency
24. Testing the innate immune system
25. Testing the
adaptive immune system
26. Periodic fever syndromes and autoinflammatory
diseases
27. Immunological dysfunction disorders
28. The AIDS workup
29.
Basic workup for autoimmune diseases
30. Neuroimmunology
31. Genetic testing
Section D: Treatment of allergic and immunologic diseases
32. Immunotherapy
to environmental allergens
33. Drug allergy desensitization methods
34. Oral,
sublingual and dermatologic immunotherapy to food allergens
35. Conventional
medications for the treatment of allergic diseases
36. The new biologicals in
allergy
37. Action plans and quality of life evaluations
38. The treatment of
atopic dermatitis
39. The recognition and treatment of anaphylaxis
40.
Treatment of venom and other insect allergies
41. Drugs and treatment
modalities for itch and hives
42. Integrative medicine in allergy and
immunology
Section E: Treatment of immunological disorders
43. Treatment of the patient
with PIDD
44. Management of autoinflammatory syndromes and periodic fevers
45. Immunomodulatory pharmaceuticals for the treatment of immune dysfunction
46. Bone marrow transplant for the patient with monogenic PIDD
47. The
immunological management of the solid-organ transplant patient
48. Apheresis
49. Pharmaceuticals for AIDS
50. Gene therapy
Dr Chang is the current Medical Director for Pediatric Immunology, Allergy and Rheumatology at Joe DiMaggio Childrens Hospital in Florida. At the same time, he serves as Associate Program Director for the Allergy Immunology Fellowship program at the University of California at Davis. Dr. Chang has previously been Chief of the Division of Allergy and Immunology at Thomas Jefferson University and Nemours Childrens Hospital in Philadelphia, PA and Wilmington, DE, respectively. He is a fellow of the American Academy of Allergy, Asthma and Immunology (AAAAI) and the American College of Allergy, Asthma and Immunology (ACAAI), and a member of the Clinical Immunology Society (CIS) and the American Association of Immunologists (AAI). He is Chair of the Core Curriculum, Education and Residency Review Committee of the AAAAI and Vice-chair of the Training Program Directors Committee of the ACAAI. He has over 100 original publications and has authored over 20 chapters in immunology, rheumatology and allergy books, and has also edited 2 books with a third on the way. He has over 30 years experience in the practice of Immunology and Allergy and has been involved in the education of future allergists and immunologists at the levels of the medical student, resident and fellow
