Muutke küpsiste eelistusi

Alpha-1 Antitrypsin: Methods and Protocols 2024 ed. [Kõva köide]

  • Formaat: Hardback, 193 pages, kõrgus x laius: 254x178 mm, kaal: 591 g, 27 Illustrations, color; 7 Illustrations, black and white, 1 Hardback
  • Sari: Methods in Molecular Biology 2750
  • Ilmumisaeg: 19-Dec-2023
  • Kirjastus: Humana
  • ISBN-10: 1071636049
  • ISBN-13: 9781071636046
Teised raamatud teemal:
  • Kõva köide
  • Hind: 150,78 €*
  • * hind on lõplik, st. muud allahindlused enam ei rakendu
  • Tavahind: 177,39 €
  • Säästad 15%
  • Raamatu kohalejõudmiseks kirjastusest kulub orienteeruvalt 3-4 nädalat
  • Kogus:
  • Lisa ostukorvi
  • Tasuta tarne
  • Tellimisaeg 2-4 nädalat
  • Lisa soovinimekirja
  • Formaat: Hardback, 193 pages, kõrgus x laius: 254x178 mm, kaal: 591 g, 27 Illustrations, color; 7 Illustrations, black and white, 1 Hardback
  • Sari: Methods in Molecular Biology 2750
  • Ilmumisaeg: 19-Dec-2023
  • Kirjastus: Humana
  • ISBN-10: 1071636049
  • ISBN-13: 9781071636046
Teised raamatud teemal:
This volume provides a collection of protocols that will allow researchers to further explore the multiple, fascinating activities of  Alpha-1 Antitrypsin (AAT) isoforms in innate immunity, and gene therapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.





 





Authoritative and cutting-edge, Alpha-1 Antitrypsin: Methods and Protocols aims to ensure successful results in the further study of this vital field.
 Introduction: Alpha-1 Antitrypsin Deficiency.- Approaches to
Therapeutic Gene Editing in Alpha-1 Antitrypsin Deficiency.-Manipulation of
Proteostasis Networks in Transgenic ZAAT Zebrafish via CRISPR-Cas9 Gene
Editing.- PCR Analysis to Identify AAT Gene Promoters and Splice
Variants.- Native and Ion Mobility Mass Spectrometry Characterization of
Alpha-1 Antitrypsin Variants and Oligomers.- Sanger and Next Generation
Sequencing of AAT.- Measuring the Concentration of Active Alpha-1 Antitrypsin
in Serum.- Characterization of Novel Alpha-1 Antitrypsin Coding Variants in a
Mammalian Cellular Model.- Alpha-1 Antitrypsin (A1AT) Proteotyping by
LC-MS/MS.- Serum Western Blot for the Detection of a c-Myc Protein Tag in
Non-Human Primates and Mice.- An Enzyme-Linked Immunosorbent Assay (ELISA)
for Quantification of Circulating Pi*Z Alpha-1 Antitrypsin
Polymers.- Measuring of Alpha1 Antitrypsin Concentration by Nephelometry or
Turbidimetry.- Autoantibody Recognition of Natural and Homocysteinylated
Alpha-1 Antitrypsin: Indirect Enzyme-Linked ImmunoSorbent Assay (ELISA)
Quantification in Sera.- Monitoring the Secretion and Activity of Alpha-1
Antitrypsin in Various Mammalian Cell Types.- Lipoproteins in Negative
Feedback with Alpha-1 Antitrypsin.- Silencing Very Low Density Lipoprotein
Receptor Reveals Alpha-1 Antitrypsin Role in HIV infectivity.- Purified
versus Plasma Alpha-1 Antitrypsin Effects on Cellular Activities.