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Amyotrophic Lateral Sclerosis, Second Edition 2nd edition [Pehme köide]

Edited by (Massachusetts General Hospital, Charlestown, USA), Edited by (The Royal London Hospital, London, UK), Edited by (Massachusetts Gen. Hosp East, Charlestown, Massachusetts, US)
  • Formaat: Paperback / softback, 392 pages, kõrgus x laius: 246x189 mm, kaal: 816 g
  • Ilmumisaeg: 05-Sep-2019
  • Kirjastus: CRC Press
  • ISBN-10: 0367390639
  • ISBN-13: 9780367390631
Teised raamatud teemal:
  • Formaat: Paperback / softback, 392 pages, kõrgus x laius: 246x189 mm, kaal: 816 g
  • Ilmumisaeg: 05-Sep-2019
  • Kirjastus: CRC Press
  • ISBN-10: 0367390639
  • ISBN-13: 9780367390631
Teised raamatud teemal:
Amyotrophic lateral sclerosis or motor neurone disease is one of the most debilitating and devastating of the neurological diseases. The only comprehensive textbook available on the topic, this completely reorganized and expanded new edition examines all aspects of ALS from pathology to patient care and provides the reader with a ready reference to help with the difficulties encountered in patient diagnosis and treatment. Undoubtedly an important work in the field, this book will be of great interest to clinical neurologists and trainees, and to all those concerned with the care of people with ALS.

Arvustused

"an extremely good book. The chapters are authoritative, clearly written, relatively concise, and well referenced. Although this book is a second edition, it is not mean to replace, but rather to supplement, the first edition." -Doody's Review Services



"The current edition is not merely an update of the first one; new authors have been recruited and chapter titles reflect changing concepts of pathogenesis.It is difficult to think of any important topics that have been omitted. Clinicians working with patients, the patients and their families, and investigators will appreciate this new, up-to-date, thorough, and handsomely produced volume."

-Lewis P. Rowland, Eleanor and Lou Gehrig MDA/ALS Center, Neurological Institute, Columbia University Medical Center, New York, New York

List of contributors
vii
Preface xi
Foreword xiii
Color section xv
Section 1 Clinical data
1(42)
1 The spectrum of motor neuron disorders
3(22)
Brian Murray
Hiroshi Mitsumoto
2 Epidemiology of amyotrophic lateral sclerosis
25(18)
Lorene M. Nelson
Valerie McGuire
Section 2 Functional studies
43(96)
3 Neuroimaging in amyotrophic lateral sclerosis
45(24)
Martin R. Turner
Victoria Williams
Camilla Blain
Derek Jones
Blot Koritnik
P. Nigel Leigh
4 Motor unit number estimation in amyotrophic lateral sclerosis
69(14)
Devanand Jillapalti
Jeremy M. Shefner
5 The corticomotoneuronal system in amyotrophic lateral sclerosis
83(22)
Markus Weber
6 Conventional neurophysiology in amyotrophic lateral sclerosis
105(20)
Mamede de Carvalho
Michael Swash
7 The neuropsychology of amyotrophic lateral sclerosis
125(14)
Jennifer Murphy
Cathy Lomen-Hoerth
Section 3 Genetics of amyotrophic lateral sclerosis and related disorders
139(100)
8 Familial motor neuron diseases other than amyotrophic lateral sclerosis
141(46)
Alice Brockington
Pamela J. Shaw
9 Amyotrophic lateral sclerosis genetics with Mendelian inheritance
187(22)
Peter M. Andersen
10 Modifying genes in amyotrophic lateral sclerosis
209(16)
Claire L. Simpson
Ammar Al-Chalabi
11 From genetic defects to molecular pathogenesis of memory and movement disorders
225(14)
William H. Stoothoff
Bradley T. Hyman
Section 4 Pathogenic mechanisms
239(94)
12 Transgenic mouse and mutagenesis models
241(16)
Ludo Van Den Bosch
Wim Robberecht
13 Apoptotic cell death pathways in amyotrophic lateral sclerosis: a review
257(12)
Piera Pasinelli
Robert H. Brown Jr
14 Amyotrophic lateral sclerosis and neurodegeneration: possible insights from the molecular biology of aging
269(14)
Anne-Marie A. Wills
Robert H. Brown Jr
15 Neurotrophic factors
283(26)
Michael Sendtner
16 Axonal transport and amyotrophic lateral sclerosis
309(14)
Andy Grierson
Chris Miller
17 Mitochondrial dysfunction and energy metabolism in amyotrophic lateral sclerosis
323(10)
Giovanni Manfredi
M. Flint Beal
Section 5 Therapy of amyotrophic lateral sclerosis and related disorders
333(30)
18 Therapeutic trials in amyotrophic lateral sclerosis: past, present and future
335(22)
Jacqueline Lau
Robin Conwit
Robert Miller
Merit Cudkowicz
19 Palliative care and quality of life in amyotrophic lateral sclerosis
357(6)
David Oliver
Gian Domenico Borasio
Index 363
Robert H. Brown, Micheal Swash, Piera Pasinelli