Providing an annual review of advances in the field of medicinal chemistry, and the chemistry of drug development, this book is aimed at pharmacologists, chemists and physicians.
CNS agents, J.M. McCall; new anxiolytics, L.J. Browne and K.J. Shaw;
recent advances in excitatory amino acid research, G.Johnson and C.F. Bigge;
progress in anti-depressant drugs, D.W. Robertson and R.W. Fuller; diversity
of neuronal calcium channels, N.A. Saccomano and A.H. Ganong; recent advances
in neurokinin receptor anatagonists, M.E. Logan, et al; antipsychotics, L.D.
Wise and T.G. Heffner; cardiovascular and pulmonary agents, D.W. Robertson;
angiotensin/renin modulators, W.J. Greenlee and P.K.S. Siegl; potassium
channel activators, J.M. Evans and S.D. Longman; endogenous vasoactive
peptides, A.M. Doherty; emerging drug discovery targets in thrombosis and
coagulation, R.J. Shebuski; serotonin modulators and
cardiovascular/gastrointestinal disease, J.E. Audia and M.L. Cohen; pulmonary
and anti-allergy agents, D.J. Wolanin and J.B. Campbell; chemotherapeutic
agents, J.J. Plattner; antibacterial agents, K.E. Brighty and P.R. McGuirk;
antiviral agents, M.M. Mansuri and J.C. Martin; HIV protease inhibitors, D.W.
Norbeck and D.J. Kempf; radiosensitizers, M.J. Suto; antiparasitic agents,
D.M. Schmatz and J.M. Schaeffer; function of human retrovirus regulatory
proteins, C.A. Rosen and S.M. Ruben; immunology, endocrinology and metabolic
diseases, W.F. Michne; chemical basis for immune mediated idiosyncratic drug
hypersensitivity, M.A. Sanner and T.J. Higgins; cholecystokinin agonists and
antagonists, A.M. Nadzan and J.F. Kerwin; recent advances in bone metabolism
and osteoporosis research, T.J. Caggiano, et al; mechanism-based
immunosuppressants, J.R. Luly; topics in biology, K.B. Seamon; cytokin
receptors, D.L. Urdal; amyloidogenesis as a therapeutic target in Alzheimer's
disease, B.D. Greenberg and F.J. Kezdy; bacterial adhesins, J. London;
regulation of the ras GTPase cycle, G. Bollag, et al; topics in drug design
and discovery, M.C. Venuti; the search for molecular diversity (1) natural
products, L.J. Nisbet and P.J. Hylands; the search for molecular diversity
(2) recombinant and synthetic randomized peptide libraries, W.J. Dower and
S.P.A. Fodor; receptor modeling by distance geometry, J.M. Blaney and J.S.
Dixon; sequence-defined oligonucleotides as potential therapeutics, M.D.
Matteucci and N. Bischofberger; trends and perspectives, J.A. Bristol; to
market, to market - 1990, J.D. Strupczewski, et al; perspectives on human
gene therapy, G.J. Nabel and E.G. Nabel.
