This book is intended for specialists of B-cell immunology. It investigates such topics as movement of a monoclonal antibody from the laboratory into the clinic, the field of Fc receptors, and the impact of monoclonal antibodies on the diagnosis and treatment of human diseases.
Preface vii Preface: Volume 5 ix List of Contributors xi The Evolution of MAbs from Research Reagents to Mainstream Commercial Therapeutics 1(42) Roland Newman Thomas Ryskamp Fc Receptors 43(80) Marc Daeron Monoclonal Antibodies in Diagnosis, Prognosis, and Therapy of Human Carcinomas: Clinical Impact 20 Years Later 123(28) M. I. Colnaghi S. Canevari S. Menard Expression of the Immunoglobulin Lambda Locus in the Mouse 151(24) Pierre Sanchez Soulef Hachemi-Rachedi Pierre Boudinot Pierre-Andre Cazenave Structural Bases of Light Chain-Related Pathology 175(34) Fred J. Stevens Deborah T. Weiss Alan Solomon Index 209(8) Index to Volume 1 217(12) Index to Volume 2 229(6) Index to Volume 3 235(8) Index to Volume 4 243(8) Contents of Previous Volumes 251
Zanetti, Maurizio; Capra, Donald J.
