Behçets disease is characterized by mucocutaneous symptoms, which are crucial for diagnosing the condition. However, the clinical spectrum of this multisystem inflammatory disease varies significantly, requiring tailored treatment strategies that consider the specific manifestations, their severity, and frequency. This complete, handy guide built by experienced experts offers detailed explanation of controversies and specifics of the diagnosis process, ensuring any clinician reading this book has the capacity to diagnose a patient with Behçets disease. All dermatology sections and subsections cover classic and rare disease manifestations with a unique set of high quality colour pictures. The treatment sections provide separate chapters for topical and systemic treatment of mucocutaneous and systemic findings. The treatment chapters for the algorithmic approach and treatment of special groups (pregnant, lactation) will help professionals from different disciplines to assess, consult, treat and follow up patient. Dermatologists, rheumatologists, ophthalmologists, and other specialists dealing with the disease encounter patients with various phenotypes of Behçets disease, each bringing a unique perspective on its clinical presentation, pathogenesis, and treatment. Behçets Disease: An Integrated Approach carefully integrates these expert viewpoints, creating a comprehensive guide for clinicians across multiple disciplines.
1. Hulusi Behçet; highlights from his personal and professional life.-
2. Historical aspects and description of Behçets disease.-
3. Behçets
disease epidemiology and geographical variations.-
4. What do the genetic
studies tell us about Behçet disease?.-
5. How Behçet's disease occurs:
disease mechanisms.-
6. Microbiota; does it have a role in the development
and severity of the disease?.-
7. Mucocutaneous manifestations and
differential diagnosis in Behçets disease.-
8. Specificity of papulopustular
lesions in the diagnosis of Behçets disease.-
9. Skin pathergy test; how
important is it for Behcets disease?.-
10. Topical treatment approaches of
mucocutaneous Behçet's disease.-
11. Systemic treatments for mucocutaneous
Behçets disease.-
12. Algorithmic approach to the treatment of Behçets
disease.-
13. Eye disease in Behçets disease.-
14. Musculoskeletal
manifestations in Behçets syndrome.-
15. Clinical features and diagnostic
tools in vascular and cardiac involvement of Behçets disease.-
16.
Management of cardiovascular involvement in Behçets disease.-
17. Surgical
approach in cardiovascular involvement of Behçet's disease.-
18. Behçet's
disease and nervous system involvement.-
19. Gastrointestinal manifestations
in Behçet's disease.-
20. How should we diagnose Behçets disease?.-
21.
Pathology of skin manifestations in Behçet disease.-
22. Activity scales used
in Behçets disease.-
23. Quality of life and scales used in Behçet's
disease.-
24. Clinical features and differential diagnosis in pediatric
Behçets disease.-
25. Treatment and prognosis of pediatric Behçets
disease.-
26. Treatment algorithms in patients with Behçet's disease during
pregnancy and lactation.-
27. Prognosis in Behçet's disease: What to
expect?.-
28. Future directions of Behcets disease.
Erkan Alpsoy, professor of dermatology who has extensive experience and academic interest in various skin disorders such as Behçets disease, psoriasis, hidradenitis suppurativa, atopic dermatitis, and Fabry disease. He is a member of several international societies such as the European Academy of Dermatology and Venereology and the European Society for Dermatologic Research. Alpsoy was included in the "World's Most Influential Scientists" list compiled by Stanford University in 2024 and published by Plos Biology. He has published many articles on Behçets disease and has contributed to various studies, including a randomized, placebo-controlled, and double-blind study on interferon alpha-2a in the treatment of Behçet disease.
Aye Boyvat is a highly experienced professor of dermatology with a particular focus on Behçet's disease, which has led to her lecturing extensively on national and international events. In addition to Behçet's disease, her academic interests include vasculitis, contact dermatitis, and atopic dermatitis. Aye Boyvat is running one of the largest Behçets disease centers in Turkey in Ankara University. She is a member of EULAR MHC-I-opathy group focusing on Behçets disease, psoriasis and ankylosing spondyloarthropathy.
Tülin Ergün is a qualified dermatology professor and a researcher experienced in Behçets disease. She has academic interests in psoriasis, connective tissue disorders, Behçets Disease, Hidradenitis suppurativa, and research ethics. Ergün has several selected publications on Behçets disease, including studies on the histopathology of the spontaneous pustules, the efficacy of topical cyclosporine-A, the anti-inflammatory and regulatory effects of Thalidomide, and the effects of azithromycin on intracellular cytokine responses and mucocutaneous manifestations. Additionally, her recent studies focus on the venous vessel wall thickness in lower extremity and the efficacy of TNF inhibitors for refractory vascular Behçet's disease.
