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Biological Science, Books a la Carte Edition 6th ed. [köitmata]

(Utah State University), (University of Washington), (Salisbury University), (College of William and Mary), (California Polytechnic State University San Luis Obispo), (California Polytechnic State University in San Luis Obispo), (Uni)
  • Formaat: Loose-leaf, 1360 pages, kõrgus x laius x paksus: 274x226x43 mm, kaal: 3057 g
  • Ilmumisaeg: 15-Jan-2016
  • Kirjastus: Pearson
  • ISBN-10: 0134243064
  • ISBN-13: 9780134243061
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  • Formaat: Loose-leaf, 1360 pages, kõrgus x laius x paksus: 274x226x43 mm, kaal: 3057 g
  • Ilmumisaeg: 15-Jan-2016
  • Kirjastus: Pearson
  • ISBN-10: 0134243064
  • ISBN-13: 9780134243061
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&>NOTE: This edition features the same content as the traditional text in a convenient, three-hole-punched, loose-leaf version. Books a la Carte also offer a great value–this format costs significantly less than a new textbook. Before purchasing, check with your instructor or review your course syllabus to ensure that you select the correct ISBN. Several versions of Pearsons MyLab & Mastering products exist for each title, including customized versions for individual schools, and registrations are not transferable. In addition, you may need a CourseID, provided by your instructor, to register for and use Pearsons MyLab & Mastering products.For introductory courses for biology majors.   Uniquely engages biology students in active learning, scientific thinking, and skill development.Scott Freeman’s Biological Science is beloved for its Socratic narrative style, its emphasis on experimental evidence, and its dedication to active learning. Science education research indicates that true mastery of content requires a move away from memorization towards active engagement with the material in a focused, personal way.Biological Science is designed to equip students with strategies to assess their level of understanding and identify the types of cognitive skills that need improvement. With the Sixth Edition, content has been streamlined with an emphasis on core concepts and core competencies from theVision and Change in Undergraduate Biology Education report. The text’s unique BioSkills section is now placed after Chapter 1 to help students develop key skills needed to become a scientist, new “Making Models” boxes guide learners in interpreting and creating models, and new “Put It all Together” case studies conclude each chapter and help students see connections between chapter content and current, real-world research questions. New, engaging content includes updated coverage of global climate change, advances in genetic editing, and recent insights into the evolution of land plants. Strong media Integration supports book features with MasteringBiology activities, Learning Catalytics™, and new whiteboard videos that guide students in completing “Making Models” assignments. Also available with MasteringBiology™ MasteringBiology from Pearson is the leading online homework, tutorial, and assessment system, designed to improve results by engaging students before, during, and after class with powerful content and activities. Instructors ensure students arrive ready to learn by assigning educationally effective content before class and encourage critical thinking and retention with in-class resources such as Learning Catalytics™. Students can further master concepts after class through traditional and adaptive homework assignments that provide hints and answer-specific feedback. The Mastering gradebook records scores for all automatically graded assignments in one place, while diagnostic tools give instructors access to rich data to assess student understanding and misconceptions.  NOTE: You are purchasing a standalone product; MyLab™ & Mastering™ does not come packaged with this content. Students, if interested in purchasing this title with MyLab & Mastering, ask your instructor for the correct package ISBN and Course ID. Instructors, contact your Pearson representative for more information.If you would like to purchase both the physical text and MyLab & Mastering, search for: 0321993756 / 9780321993755     Biological Science Plus MasteringBiology with eText -- Access Card Package, 6/e Package consists of:0134261992 / 9780134261997     MasteringBiology with Pearson eText -- ValuePack Access Card -- for Biological Science0321976495 / 9780321976499     Biological Science
1 Biology and the Tree of Life
1(15)
1.1 What Does It Mean to Say That Something Is Alive?
2(1)
1.2 Life Is Cellular
2(2)
All Organisms Are Made of Cells
2(1)
Where Do Cells Come From?
3(1)
Life Replicates Through Cell Division
4(1)
1.3 Life Evolves
4(1)
What Is Evolution?
4(1)
What Is Natural Selection?
4(1)
1.4 Life Processes Information
5(1)
The Central Dogma
5(1)
Life Requires Energy
6(1)
1.5 The Tree of Life
6(3)
Using Molecules to Understand the Tree of Life
6(2)
How Should We Name Branches on the Tree of Life?
8(1)
1.6 Doing Biology
9(5)
The Nature of Science
9(1)
Why Do Giraffes Have Long Necks? An Introduction to Hypothesis Testing
9(2)
How Do Ants Navigate? An Introduction to Experimental Design
11(3)
Chapter Review
14(2)
BioSkills Doing Biology
16(39)
B.1 Using the Metric System and Significant Figures
19(2)
Metric System Units and Conversions
19(1)
Significant Figures
20(1)
B.2 Reading and Making Graphs
21(3)
Getting Started
21(2)
Types of Graphs
23(1)
Getting Practice
23(1)
B.3 Interpreting Standard Error Bars and Using Statistical Tests
24(2)
Standard Error Bars
24(1)
Using Statistical Tests
25(1)
Interpreting P Values and Statistical Significance
25(1)
B.4 Working with Probabilities
26(1)
The Both-And Rule
26(1)
The Either-Or Rule
26(1)
B.5 Using Logarithms
27(1)
B.6 Separating and Visualizing Molecules
28(3)
Using Electrophoresis to Separate Molecules
28(1)
Using Thin Layer Chromatography to Separate Molecules
29(1)
Visualizing Molecules
29(2)
B.7 Separating Cell Components by Centrifugation
31(2)
B.8 Using Spectrophotometry
33(1)
B.9 Using Microscopy
33(3)
Light and Fluorescence Microscopy
33(1)
Electron Microscopy
34(1)
Studying Live Cells and Real-Time Processes
35(1)
Visualizing Cellular Structures in 3-D
35(1)
B.10 Using Molecular Biology Tools and Techniques
36(5)
Making and Using DNA Libraries
36(1)
Amplifying DNA Using the Polymerase Chain Reaction (PCR)
37(1)
Dideoxy Sequencing
38(1)
Shotgun Sequencing
39(1)
DNA Microarray
40(1)
B.11 Using Cell Culture and Model Organisms as Tools
41(4)
Cell and Tissue Culture Methods
41(1)
Model Organisms
42(3)
B.12 Reading and Making Visual Models
45(2)
Tips for Interpreting Models
45(1)
Tips for Making your Own Models
46(1)
Concept Maps
46(1)
B.13 Reading and Making Phylogenetic Trees
47(2)
Anatomy of a Phylogenetic Tree
47(1)
How to Read a Phylogenetic Tree
48(1)
How to Draw a Phylogenetic Tree
48(1)
B.14 Reading Chemical Structures
49(1)
B.15 Translating Greek and Latin Roots in Biology
50(1)
B.16 Reading and Citing the Primary Literature
50(2)
What Is the Primary Literature?
50(1)
Getting Started
50(2)
Citing Sources
52(1)
Getting Practice
52(1)
B.17 Recognizing and Correcting Misconceptions
52(1)
B.18 Using Bloom's Taxonomy for Study Success
53(2)
Categories of Human Cognition
53(1)
Six Study Steps to Success
53(2)
Unit 1 The Molecular Origin And Evolution Of Life 55(87)
2 Water and Carbon: The Chemical Basis of Life
55(23)
2.1 Atoms, Ions, and Molecules: The Building Blocks of Chemical Evolution
56(5)
Basic Atomic Structure
56(2)
How Does Covalent Bonding Hold Molecules Together?
58(1)
Ionic Bonding, Ions, and the Electron-Sharing Continuum
59(1)
Some Simple Molecules Formed from C, H, N, and O
60(1)
The Geometry of Simple Molecules
60(1)
Representing Molecules
60(1)
2.2 Properties of Water and the Early Oceans
61(6)
Why Is Water Such an Efficient Solvent?
62(1)
What Properties Are Correlated with Water's Structure?
62(3)
The Role of Water in Acid-Base Chemical Reactions
65(2)
2.3 Chemical Reactions, Energy, and Chemical Evolution
67(3)
How Do Chemical Reactions Happen?
67(1)
What Is Energy?
68(1)
What Makes a Chemical Reaction Spontaneous?
68(2)
2.4 Model Systems for Investigating Chemical Evolution
70(3)
Early Origin-of-Life Experiments
70(1)
Recent Origin-of-Life Experiments
71(2)
2.5 The Importance of Organic Molecules
73(2)
Linking Carbon Atoms Together
73(2)
Functional Groups
75(1)
Chapter Review
75(3)
3 Protein Structure and Function
78(15)
3.1 Amino Acids and Their Polymerization
79(4)
The Structure of Amino Acids
79(1)
The Nature of Side Chains
79(2)
How Do Amino Acids Link to Form Proteins?
81(2)
3.2 What Do Proteins Look Like?
83(5)
Primary Structure
84(1)
Secondary Structure
85(1)
Tertiary Structure
86(1)
Quaternary Structure
87(1)
3.3 Folding and Function
88(2)
Normal Folding Is Crucial to Function
88(1)
Protein Shape Is Flexible
89(1)
3.4 Protein Functions Are as Diverse as Protein Structures
90(1)
Why Are Enzymes Good Catalysts?
90(1)
Did Life Arise from a Self-Replicating Enzyme?
91(1)
Chapter Review
91(2)
4 Nucleic Acids and the RNA World
93(14)
4.1 What Is a Nucleic Acid?
94(3)
Could Chemical Evolution Result in the Production of Nucleotides?
95(1)
How Do Nucleotides Polymerize to Form Nucleic Acids?
95(2)
4.2 DNA Structure and Function
97(4)
What Is the Nature of DNA's Secondary Structure?
97(2)
The Tertiary Structure of DNA
99(1)
DNA Functions as an Information-Containing Molecule
99(1)
The DNA Double Helix Is a Stable Structure
100(1)
4.3 RNA Structure and Function
101(2)
Structurally, RNA Differs from DNA
101(1)
RNA's Versatility
102(1)
RNA Can Function as a Catalytic Molecule
102(1)
4.4 In Search of the First Life-Form
103(2)
How Biologists Study the RNA World
104(1)
The RNA World May Have Sparked the Evolution of Life
104(1)
Chapter Review
105(2)
5 An Introduction to Carbohydrates
107(12)
5.1 Sugars as Monomers
108(2)
What Distinguishes One Monosaccharide from Another?
108(1)
Can Monosaccharides Form by Chemical Evolution?
109(1)
5.2 The Structure of Polysaccharides
110(3)
Starch: A Storage Polysaccharide in Plants
111(1)
Glycogen: A Highly Branched Storage Polysaccharide in Animals
111(2)
Cellulose: A Structural Polysaccharide in Plants
113(1)
Chitin: A Structural Polysaccharide in Fungi and Animals
113(1)
Peptidoglycan: A Structural Polysaccharide in Bacteria
113(1)
Polysaccharides and Chemical Evolution
113(1)
5.3 What Do Carbohydrates Do?
113(4)
Carbohydrates Can Provide Structural Support
114(1)
The Role of Carbohydrates in Cell Identity
114(1)
Carbohydrates and Energy Storage
115(2)
Chapter Review
117(2)
6 Lipids, Membranes, and the First Cells
119(21)
6.1 Lipid Structure and Function
120(3)
How Does Bond Saturation Affect Hydrocarbon Structure?
120(1)
A Look at Three Types of Lipids Found in Cells
121(1)
How Membrane Lipids Interact with Water
122(1)
Were Lipids Present during Chemical Evolution?
123(1)
6.2 Phospholipid Bilayers
123(4)
Artificial Membranes as an Experimental System
124(1)
Selective Permeability of Lipid Bilayers
124(1)
How Does Lipid Structure Affect Membrane Permeability?
125(1)
How Does Temperature Affect the Fluidity and Permeability of Membranes?
126(1)
6.3 How Substances Move across Lipid Bilayers: Diffusion and Osmosis
127(3)
Diffusion
127(1)
Osmosis
128(1)
Membranes and Chemical Evolution
129(1)
6.4 Proteins Alter Membrane Structure and Function
130(8)
Development of the Fluid-Mosaic Model
130(2)
Systems for Studying Membrane Proteins
132(1)
Channel Proteins Facilitate Diffusion
132(2)
Carrier Proteins Facilitate Diffusion
134(1)
Pumps Perform Active Transport
135(2)
Plasma Membranes Define the Intracellular Environment
137(1)
Chapter Review
138(2)
Big Picture: The Chemistry of Life
140(2)
Unit 2 Cell Structure And Function 142(129)
7 Inside the Cell
142(29)
7.1 Bacterial and Archaeal Cell Structures and Their Functions
143(3)
A Revolutionary New View
143(1)
Prokaryotic Cell Structures: A Parts List
143(3)
7.2 Eukaryotic Cell Structures and Their Functions
146(8)
The Benefits of Organelles
146(1)
Eukaryotic Cell Structures: A Parts List
146(8)
7.3 Putting the Parts into a Whole
154(1)
Structure and Function at the Whole-Cell Level
154(1)
The Dynamic Cell
154(1)
7.4 Cell Systems I: Nuclear Transport
155(2)
Structure and Function of the Nuclear Envelope
155(1)
How Do Molecules Enter the Nucleus?
156(1)
7.5 Cell Systems II: The Endomembrane System Manufactures, Ships, and Recycles Cargo
157(6)
Studying the Pathway through the Endomembrane System
157(2)
Entering the Endomembrane System: The Signal Hypothesis
159(1)
Moving from the ER to the Golgi Apparatus
160(1)
What Happens Inside the Golgi Apparatus?
160(1)
How Do Proteins Reach Their Destinations?
160(1)
Recycling Material in the Lysosome
160(3)
7.6 Cell Systems III: The Dynamic Cytoskeleton
163(5)
Actin Filaments
163(1)
Intermediate Filaments
164(1)
Microtubules
164(2)
Flagella and Cilia: Moving the Entire Cell
166(2)
Chapter Review
168(3)
8 Energy and Enzymes: An Introduction to Metabolism
171(18)
8.1 What Happens to Energy in Chemical Reactions?
172(3)
Chemical Reactions Involve Energy Transformations
172(1)
Temperature and Concentration Affect Reaction Rates
173(2)
8.2 Nonspontaneous Reactions May Be Driven Using Chemical Energy
175(4)
Redox Reactions Transfer Energy via Electrons
175(2)
ATP Transfers Energy via Phosphate Groups
177(2)
8.3 How Enzymes Work
179(3)
Enzymes Help Reactions Clear Two Hurdles
179(2)
What Limits the Rate of Catalysis?
181(1)
Do Enzymes Work Alone?
182(1)
8.4 What Factors Affect Enzyme Function?
182(2)
Enzymes Are Optimized for Particular Environments
182(1)
Most Enzymes Are Regulated
183(1)
8.5 Enzymes Can Work Together in Metabolic Pathways
184(2)
Metabolic Pathways Are Regulated
185(1)
Metabolic Pathways Evolve
185(1)
Chapter Review
186(3)
9 Cellular Respiration and Fermentation
189(21)
9.1 An Overview of Cellular Respiration
190(3)
What Happens When Glucose Is Oxidized?
190(2)
Cellular Respiration Plays a Central Role in Metabolism
192(1)
9.2 Glycolysis: Oxidizing Glucose to Pyruvate
193(3)
Glycolysis Is a Sequence of 10 Reactions
193(1)
How Is Glycolysis Regulated?
194(2)
9.3 Processing Pyruvate to Acetyl CoA
196(1)
9.4 The Citric Acid Cycle: Oxidizing Acetyl CoA to CO2
197(3)
How Is the Citric Acid Cycle Regulated?
197(2)
What Happens to the NADH and FADH2?
199(1)
9.5 Electron Transport and Chemiosmosis: Building a Proton Gradient to Produce ATP
200(6)
The Electron Transport Chain
201(2)
The Discovery of ATP Synthase
203(1)
The Chemiosmosis Hypothesis
203(2)
Organisms Use a Diversity of Electron Acceptors
205(1)
9.6 Fermentation
206(2)
Many Different Fermentation Pathways Exist
206(1)
Fermentation as an Alternative to Cellular Respiration
207(1)
Chapter Review
208(2)
10 Photosynthesis
210(22)
10.1 Photosynthesis Harnesses Sunlight to Make Carbohydrate
211(2)
Photosynthesis: Two Linked Sets of Reactions
211(1)
Photosynthesis Occurs in Chloroplasts
212(1)
10.2 How Do Pigments Capture Light Energy?
213(5)
Photosynthetic Pigments Absorb Light
213(3)
When Light Is Absorbed, Electrons Enter an Excited State
216(2)
10.3 The Discovery of Photosystems I and II
218(5)
How Does Photosystem II Work?
218(2)
How Does Photosystem I Work?
220(1)
The Z Scheme: Photosystems II and I Work Together
221(2)
10.4 How Is Carbon Dioxide Reduced to Produce Sugars?
223(7)
The Calvin Cycle Fixes Carbon
223(2)
The Discovery of Rubisco
225(1)
How Is Photosynthesis Regulated?
226(1)
Oxygen and Carbon Dioxide Pass through Stomata
227(1)
Mechanisms for Increasing CO2 Concentration
227(2)
What Happens to the Sugar That Is Produced by Photosynthesis?
229(1)
Chapter Review
230(2)
Big Picture: Energy for Life
232(2)
11 Cell-Cell Interactions
234(19)
11.1 The Cell Surface
235(3)
The Structure and Function of an Extracellular Layer
235(1)
The Extracellular Matrix in Animals
235(1)
The Cell Wall in Plants
236(2)
11.2 How Do Adjacent Cells Connect and Communicate?
238(5)
Cell-Cell Attachments in Multicellular Eukaryotes
238(3)
Cells Communicate via Cell-Cell Gaps
241(2)
11.3 How Do Distant Cells Communicate?
243(6)
Cell-Cell Signaling in Multicellular Organisms
243(1)
Signal Reception
243(1)
Signal Processing
244(4)
Signal Response
248(1)
Signal Deactivation
248(1)
Crosstalk: Synthesizing Input from Many Signals
248(1)
11.4 Signaling between Unicellular Organisms
249(1)
Chapter Review
250(3)
12 The Cell Cycle
253(18)
12.1 How Do Cells Replicate?
254(3)
What Is a Chromosome?
254(1)
Cells Alternate between M Phase and Interphase
255(1)
The Discovery of S Phase
255(1)
The Discovery of the Gap Phases
255(1)
The Cell Cycle
256(1)
12.2 What Happens during M Phase?
257(6)
Events in Mitosis
257(3)
How Do Chromosomes Move during Anaphase?
260(2)
Cytokinesis Results in Two Daughter Cells
262(1)
Bacterial Cell Replication
262(1)
12.3 Control of the Cell Cycle
263(3)
The Discovery of Cell-Cycle Regulatory Molecules
263(2)
Cell-Cycle Checkpoints Can Arrest the Cell Cycle
265(1)
12.4 Cancer: Out-of-Control Cell Division
266(3)
Properties of Cancer Cells
267(1)
Cancer Involves Loss of Cell-Cycle Control
267(2)
Chapter Review
269(2)
Unit 3 Gene Structure And Expression 271(164)
13 Meiosis
271(18)
13.1 How Does Meiosis Occur?
272(8)
Chromosomes Come in Distinct Sizes and Shapes
272(1)
The Concept of Ploidy
273(1)
An Overview of Meiosis
273(4)
The Phases of Meiosis I
277(1)
The Phases of Meiosis II
278(1)
A Closer Look at Synapsis and Crossing Over
279(1)
Mitosis versus Meiosis
279(1)
13.2 Meiosis Promotes Genetic Variation
280(3)
Chromosomes and Heredity
281(1)
The Role of Independent Assortment
281(1)
The Role of Crossing Over
282(1)
How Does Fertilization Affect Genetic Variation?
282(1)
13.3 What Happens When Things Go Wrong in Meiosis?
283(1)
How Do Mistakes Occur?
283(1)
Why Do Mistakes Occur?
284(1)
13.4 Why Does Meiosis Exist?
284(3)
The Paradox of Sex
284(1)
The Purifying Selection Hypothesis
285(1)
The Changing-Environment Hypothesis
285(2)
Chapter Review
287(2)
14 Mendel and the Gene
289(27)
14.1 Mendel's Experimental System
290(2)
What Questions Was Mendel Trying to Answer?
290(1)
The Garden Pea Served as the First Model Organism in Genetics
290(2)
14.2 Mendel's Experiments with a Single Trait
292(4)
The Monohybrid Cross
292(2)
Particulate Inheritance
294(2)
14.3 Mendel's Experiments with Two Traits
296(3)
The Dihybrid Cross
296(2)
Using a Testcross to Confirm Predictions
298(1)
14.4 The Chromosome Theory of Inheritance
299(3)
Meiosis Explains Mendel's Principles
300(1)
Testing the Chromosome Theory
300(2)
14.5 Extending Mendel's Rules
302(8)
Linkage: What Happens When Genes Are Located on the Same Chromosome?
303(3)
Quantitative Methods 14.1 Linkage and Genetic Mapping
305(1)
How Many Alleles Can a Gene Have?
306(1)
Are Alleles Always Dominant or Recessive?
306(1)
Does Each Gene Affect Just One Trait?
306(1)
Are All Traits Determined by a Gene?
307(1)
Can Mendel's Principles Explain Traits That Don't Fall into Distinct Categories?
308(2)
14.6 Applying Mendel's Rules to Human Inheritance
310(2)
Identifying Alleles as Recessive or Dominant
310(1)
Identifying Traits as Autosomal or Sex-Linked
311(1)
Chapter Review
312(4)
15 DNA and the Gene: Synthesis and Repair
316(19)
15.1 What Are Genes Made Of?
317(2)
The Hershey-Chase Experiment
317(1)
The Secondary Structure of DNA
318(1)
15.2 Testing Early Hypotheses about DNA Synthesis
319(1)
Three Alternative Hypotheses
320(1)
The Meselson-Stahl Experiment
320(1)
15.3 A Model for DNA Synthesis
320(7)
Where Does Replication Start?
322(1)
How Is the Helix Opened and Stabilized?
322(2)
How Is the Leading Strand Synthesized?
324(1)
How Is the Lagging Strand Synthesized?
324(3)
15.4 Replicating the Ends of Linear Chromosomes
327(2)
The End Replication Problem
327(1)
Telomerase Solves the End Replication Problem
328(1)
Effect of Telomere Length on Cell Division
329(1)
15.5 Repairing Mistakes and DNA Damage
329(3)
Correcting Mistakes in DNA Synthesis
330(1)
Repairing Damaged DNA
330(1)
Xeroderma Pigmentosum: A Case Study
331(1)
Chapter Review
332(3)
16 How Genes Work
335(13)
16.1 What Do Genes Do?
336(2)
The One-Gene, One-Enzyme Hypothesis
336(1)
An Experimental Test of the Hypothesis
336(2)
16.2 The Central Dogma of Molecular Biology
338(3)
The Genetic Code Hypothesis
338(1)
RNA as the Intermediary between Genes and Proteins
338(1)
Dissecting the Central Dogma
339(2)
16.3 The Genetic Code
341(2)
How Long Is a "Word" in the Genetic Code?
341(1)
How Did Researchers Crack the Code?
342(1)
16.4 What Are the Types and Consequences of Mutation?
343(3)
Point Mutations
344(1)
Chromosome Mutations
345(1)
Chapter Review
346(2)
17 Transcription, RNA Processing, and Translation
348(19)
17.1 An Overview of Transcription
349(4)
Initiation: How Does Transcription Begin in Bacteria?
349(2)
Elongation and Termination
351(1)
Transcription in Eukaryotes
351(2)
17.2 RNA Processing in Eukaryotes
353(2)
The Startling Discovery of Split Eukaryotic Genes
353(1)
RNA Splicing
353(1)
Adding Caps and Tails to Transcripts
354(1)
17.3 An Introduction to Translation
355(1)
Ribosomes Are the Site of Protein Synthesis
355(1)
Translation in Bacteria and Eukaryotes
355(1)
How Does an mRNA Triplet Specify an Amino Acid?
356(1)
17.4 The Structure and Function of Transfer RNA
356(3)
What Do tRNAs Look Like?
357(1)
How Are Amino Acids Attached to tRNAs?
358(1)
How Many tRNAs Are There?
358(1)
17.5 The Structure of Ribosomes and Their Function in Translation
359(5)
Initiating Translation
361(1)
Elongation: Extending the Polypeptide
361(1)
Terminating Translation
362(1)
Post-Translational Modifications
363(1)
Chapter Review
364(3)
18 Control of Gene Expression in Bacteria
367(12)
18.1 An Overview of Gene Regulation and Information Flow
368(2)
Mechanisms of Regulation
368(1)
Metabolizing Lactose-A Model System
369(1)
18.2 Identifying Regulated Genes
370(2)
18.3 Negative Control of Transcription
372(3)
The Operon Model
373(1)
How Does Glucose Regulate the lac Operon?
374(1)
Why Has the lac Operon Model Been So Important?
375(1)
18.4 Positive Control of Transcription
375(1)
18.5 Global Gene Regulation
376(1)
Chapter Review
377(2)
19 Control of Gene Expression in Eukaryotes
379(17)
19.1 Gene Regulation in Eukaryotes-An Overview
380(1)
19.2 Chromatin Remodeling
380(4)
What Is Chromatin's Basic Structure?
381(1)
Evidence that Chromatin Structure Is Altered in Active Genes
382(1)
How Is Chromatin Altered?
382(1)
Chromatin Modifications Can Be Inherited
383(1)
19.3 Initiating Transcription: Regulatory Sequences and Proteins
384(4)
Promoter-Proximal Elements Are Regulatory Sequences Near the Core Promoter
385(1)
Enhancers Are Regulatory Sequences Far from the Core Promoter
385(1)
The Role of Transcription Factors in Differential Gene Expression
386(1)
How Do Transcription Factors Recognize Specific DNA Sequences?
386(1)
A Model for Transcription Initiation
387(1)
19.4 Post-Transcriptional Control
388(3)
Alternative Splicing of Primary Transcripts
388(1)
How Is Translation Controlled?
389(2)
Post-Translational Control
391(1)
19.5 How Does Gene Expression Compare in Bacteria and Eukaryotes?
391(1)
19.6 Linking Cancer to Defects in Gene Regulation
392(1)
The Genetic Basis of Uncontrolled Cell Growth
392(1)
The p53 Tumor Suppressor: A Case Study
392(1)
Chapter Review
393(3)
Big Picture: Genetic Information
396(2)
20 The Molecular Revolution: Biotechnology and Beyond
398(20)
20.1 Recombinant DNA Technology
399(2)
Using Plasmids in Cloning
399(1)
Using Restriction Endonucleases and DNA Ligase to Cut and Paste DNA
399(2)
Transformation: Introducing Recombinant Plasmids into Bacterial Cells
401(1)
Using Reverse Transcriptase to Produce cDNAs
401(1)
Biotechnology in Agriculture
401(1)
20.2 The Polymerase Chain Reaction
401(2)
Requirements of PCR
401(1)
DNA Fingerprinting
402(1)
A New Branch of the Human Family Tree
402(1)
20.3 DNA Sequencing
403(2)
Whole-Genome Sequencing
404(1)
Bioinformatics
404(1)
Which Genomes Are Being Sequenced, and Why?
404(1)
Which Sequences Are Genes?
404(1)
20.4 Insights from Genome Analysis
405(6)
The Natural History of Prokaryotic Genomes
406(1)
The Natural History of Eukaryotic Genomes
407(3)
Insights from the Human Genome Project
410(1)
20.5 Finding and Engineering Genes: The Huntington Disease Story
411(3)
How Was the Huntington Disease Gene Found?
411(1)
How Are Human Genes Found Today?
412(1)
What Are the Benefits of Finding a Disease Gene?
412(1)
Can Gene Therapy Provide a Cure?
413(1)
20.6 Functional Genomics, Proteomics, and Systems Biology
414(1)
What Is Functional Genomics?
414(1)
What Is Proteomics?
414(1)
What Is Systems Biology?
414(1)
Chapter Review
415(3)
21 Genes, Development, and Evolution
418(17)
21.1 Shared Developmental Processes
419(3)
Cell Division
419(1)
Cell-Cell Interactions
420(1)
Cell Differentiation
420(1)
Cell Movement and Changes in Shape
421(1)
Programmed Cell Death
421(1)
21.2 Genetic Equivalence and Differential Gene Expression in Development
422(2)
Evidence that Differentiated Plant Cells Are Genetically Equivalent
422(1)
Evidence that Differentiated Animal Cells Are Genetically Equivalent
422(1)
How Does Differential Gene Expression Occur?
423(1)
21.3 Regulatory Cascades Establish the Body Plan
424(5)
Morphogens Set Up the Body Axes
424(2)
Regulatory Genes Provide Increasingly Specific Positional Information
426(2)
Regulatory Genes and Signaling Molecules Are Evolutionarily Conserved
428(1)
One Regulator Can Be Used Many Different Ways
429(1)
21.4 Cells Are Determined Before They Differentiate
429(2)
Commitment and Determination
430(1)
Master Regulators of Differentiation and Development
430(1)
Stem Cell Therapy
431(1)
21.5 Changes in Developmental Gene Expression Drive Evolutionary Change
431(1)
Chapter Review
432(3)
Unit 4 Evolutionary Patterns And Processes 435(83)
22 Evolution by Natural Selection
435(21)
22.1 The Rise of Evolutionary Thought
436(1)
Plato and Typological Thinking
436(1)
Aristotle and the Scale of Nature
436(1)
Lamarck and the Idea of Evolution as Change through Time
437(1)
Darwin and Wallace and Evolution by Natural Selection
437(1)
22.2 The Pattern of Evolution: Have Species Changed, and Are They Related?
437(8)
Evidence for Change through Time
437(3)
Evidence of Descent from a Common Ancestor
440(3)
Evolution's "Internal Consistency"- The Importance of Independent Data Sets
443(2)
22.3 The Process of Evolution: How Does Natural Selection Work?
445(1)
Darwin's Inspiration
445(1)
Darwin's Four Postulates
445(1)
The Biological Definitions of Fitness, Adaptation, and Selection
446(1)
22.4 Evolution in Action: Recent Research on Natural Selection
446(5)
Case Study 1: How Did Mycobacterium tuberculosis Become Resistant to Antibiotics?
446(2)
Case Study 2: Why Do Beak Sizes and Shapes Vary in Galapagos Finches?
448(3)
22.5 Debunking Common Myths about Natural Selection and Adaptation
451(3)
Natural Selection Does Not Change Individuals
451(1)
Natural Selection Is Not Goal Directed
452(1)
Natural Selection Does Not Lead to Perfection
453(1)
Chapter Review
454(2)
23 Evolutionary Processes
456(24)
23.1 Analyzing Change in Allele Frequencies: The Hardy-Weinberg Principle
457(4)
The Gene Pool Concept
457(1)
Quantitative Methods 23.1 Deriving the Hardy-Weinberg Principle
458(1)
The Hardy-Weinberg Principle Makes Important Assumptions
458(1)
How Do Biologists Apply the Hardy-Weinberg Principle to Real Populations?
459(2)
23.2 Nonrandom Mating
461(1)
How Does Inbreeding Affect Allele Frequencies and Genotype Frequencies?
461(1)
How Does Inbreeding Influence Evolution?
462(1)
23.3 Natural Selection
462(7)
How Does Selection Affect Genetic Variation?
462(4)
Sexual Selection
466(3)
23.4 Genetic Drift
469(4)
Simulation Studies of Genetic Drift
469(1)
Experimental Studies of Genetic Drift
470(2)
What Causes Genetic Drift in Natural Populations?
472(1)
23.5 Gene Flow
473(2)
Measuring Gene Flow between Populations
473(1)
Gene Flow Is Random with Respect to Fitness
474(1)
23.6 Mutation
475(3)
Mutation as an Evolutionary Process
475(1)
Experimental Studies of Mutation
475(1)
Studies of Mutation in Natural Populations
476(1)
Take-Home Messages
477(1)
Chapter Review
478(2)
24 Speciation
480(16)
24.1 How are Species Defined and Identified?
481(4)
The Biological Species Concept
481(1)
The Morphospecies Concept
482(1)
The Phylogenetic Species Concept
482(2)
Species Definitions in Action: The Case of the Dusky Seaside Sparrow
484(1)
24.2 Isolation and Divergence in Allopatry
485(2)
Allopatric Speciation by Dispersal
485(1)
Allopatric Speciation by Vicariance
486(1)
24.3 Isolation and Divergence in Sympatry
487(4)
Sympatric Speciation by Disruptive Selection
487(2)
Sympatric Speciation by Polyploidization
489(2)
24.4 What Happens When Isolated Populations Come into Contact?
491(2)
Reinforcement
491(1)
Hybrid Zones
491(1)
New Species through Hybridization
492(1)
Chapter Review
493(3)
25 Phylogenies and the History of Life
496(20)
25.1 Tools for Studying History: Phylogenetic Trees
497(6)
How Do Biologists Estimate Phylogenies?
498(2)
How Can Biologists Distinguish Homology from Homoplasy?
500(1)
Whale Evolution: A Case Study
501(2)
25.2 Tools for Studying History: The Fossil Record
503(4)
How Do Fossils Form?
503(1)
Limitations of the Fossil Record
504(1)
Life's Time Line
504(3)
25.3 Adaptive Radiation
507(4)
Why Do Adaptive Radiations Occur?
507(2)
The Cambrian Explosion
509(2)
25.4 Mass Extinction
511(2)
How Do Mass Extinctions Differ from Background Extinctions?
511(1)
The End-Permian Extinction
511(1)
The End-Cretaceous Extinction
512(1)
The Sixth Mass Extinction?
513(1)
Chapter Review
513(3)
Big Picture: Evolution
516(2)
Unit 5 The Diversification Of Life 518(186)
26 Bacteria and Archaea
518(21)
26.1 Why Do Biologists Study Bacteria and Archaea?
519(4)
Biological Impact
519(1)
Some Prokaryotes Thrive in Extreme Environments
519(1)
Medical Importance
520(2)
Role in Bioremediation
522(1)
26.2 How Do Biologists Study Bacteria and Archaea?
523(2)
Using Enrichment Cultures
523(1)
Using Metagenomics
524(1)
Investigating the Human Microbiome
524(1)
Evaluating Molecular Phylogenies
524(1)
26.3 What Themes Occur in the Diversification of Bacteria and Archaea?
525(9)
Genetic Variation through Gene Transfer
525(1)
Morphological Diversity
526(2)
Metabolic Diversity
528(3)
Ecological Diversity and Global Impacts
531(3)
26.4 Key Lineages of Bacteria and Archaea
534(3)
Bacteria
534(1)
Archaea
534(3)
Chapter Review
537(2)
27 Protists
539(22)
27.1 Why Do Biologists Study Protists?
540(3)
Impacts on Human Health and Welfare
540(2)
Ecological Importance of Protists
542(1)
27.2 How Do Biologists Study Protists?
543(3)
Microscopy: Studying Cell Structure
544(1)
Evaluating Molecular Phylogenies
544(1)
Discovering New Lineages via Direct Sequencing
545(1)
27.3 What Themes Occur in the Diversification of Protists?
546(10)
What Morphological Innovations Evolved in Protists?
546(5)
How Do Protists Obtain Food?
551(1)
How Do Protists Move?
552(1)
How Do Protists Reproduce?
552(4)
27.4 Key Lineages of Protists
556(2)
Amoebozoa
556(1)
Excavata
556(1)
Plantae
556(1)
Rhizaria
556(2)
Alveolata
558(1)
Stramenopila (Heterokonta)
558(1)
Chapter Review
558(3)
28 Green Algae and Land Plants
561(29)
28.1 Why Do Biologists Study Green Algae and Land Plants?
562(2)
Plants Provide Ecosystem Services
562(1)
Plants Provide Humans with Food, Fuel, Fiber, Building Materials, and Medicines
563(1)
28.2 How Do Biologists Study Green Algae and Land Plants?
564(4)
Analyzing Morphological Traits
564(1)
Using the Fossil Record
565(1)
Evaluating Molecular Phylogenies
566(2)
28.3 What Themes Occur in the Diversification of Land Plants?
568(13)
The Transition to Land, I: How Did Plants Adapt to Dry Conditions with Intense Sunlight?
568(3)
Mapping Evolutionary Changes on the Phylogenetic Tree
571(1)
The Transition to Land, II: How Do Plants Reproduce in Dry Conditions?
571(9)
The Angiosperm Radiation
580(1)
28.4 Key Lineages of Green Algae and Land Plants
581(7)
Green Algae
581(1)
Nonvascular Plants
582(1)
Seedless Vascular Plants
582(1)
Seed Plants: Gymnosperms and Angiosperms
582(6)
Chapter Review
588(2)
29 Fungi
590(23)
29.1 Why Do Biologists Study Fungi?
591(2)
Fungi Have Important Economic and Ecological Impacts
591(1)
Mycorrhizal Fungi Provide Nutrients for Land Plants
592(1)
Saprophytic Fungi Accelerate the Carbon Cycle on Land
593(1)
29.2 How Do Biologists Study Fungi?
593(5)
Analyzing Morphological Traits
594(2)
Evaluating Molecular Phylogenies
596(2)
29.3 What Themes Occur in the Diversification of Fungi?
598(10)
Fungi Often Participate in Symbioses
599(3)
What Adaptations Make Fungi Such Effective Decomposers?
602(1)
Variation in Reproduction
603(2)
Four Major Types of Life Cycles
605(3)
29.4 Key Lineages of Fungi
608(2)
Microsporidia
608(1)
Chytrids
609(1)
Zygomycetes
609(1)
Glomeromycota
610(1)
Basidiomycota
610(1)
Ascomycota
610(1)
Chapter Review
610(3)
30 An Introduction to Animals
613(21)
30.1 What Is an Animal?
614(1)
30.2 What Key Innovations Occurred during the Origin of Animal Phyla?
615(8)
Origin of Multicellularity
616(2)
Origin of Embryonic Tissue Layers and Muscle
618(1)
Origin of Bilateral Symmetry, Cephalization, and the Nervous System
619(2)
Origin of the Coelom
621(1)
Origin of Protostomes and Deuterostomes
622(1)
Origin of Segmentation
623(1)
30.3 What Themes Occur in the Diversification of Animals within Phyla?
623(7)
Sensory Organs
624(1)
Feeding
625(1)
Movement
626(2)
Reproduction
628(1)
Life Cycles
629(1)
30.4 Key Lineages of Animals: Non-Bilaterian Groups
630(2)
Porifera (Sponges)
630(1)
Ctenophora (Comb Jellies)
631(1)
Cnidaria (Jellyfish, Corals, Anemones, Hydroids)
631(1)
Chapter Review
632(2)
31 Protostome Animals
634(21)
31.1 What Is a Protostome?
635(2)
The Water-to-Land Transition
636(1)
Modular Body Plans
637(1)
31.2 What Is a Lophotrochozoan?
637(7)
What Is a Flatworm?
640(1)
What Is a Segmented Worm?
641(1)
What Is a Mollusk?
641(3)
31.3 What Is an Ecdysozoan?
644(9)
What Is a Roundworm?
645(1)
What Are Tardigrades and Velvet Worms?
645(1)
What Is an Arthropod?
645(3)
Arthropod Diversity
648(4)
Arthropod Metamorphosis
652(1)
Chapter Review
653(2)
32 Deuterostome Animals
655(27)
32.1 What Is an Echinoderm?
656(3)
The Echinoderm Body Plan
656(1)
Echinoderms Are Important Consumers
657(2)
32.2 What Is a Chordate?
659(2)
The Cephalochordates
660(1)
The Urochordates
660(1)
The Vertebrates
661(1)
32.3 What Is a Vertebrate?
661(1)
32.4 What Key Innovations Occurred during the Evolution of Vertebrates?
662(11)
Urochordates: Outgroup to Vertebrates
662(2)
First Vertebrates: Origin of the Cranium and Vertebrae
664(1)
Gnathostomes: Origin of the Vertebrate Jaw
665(2)
Origin of the Bony Endoskeleton
667(1)
Tetrapods: Origin of the Limb
667(1)
Amniotes: Origin of the Amniotic Egg
668(1)
Mammals: Origin of Lactation and Fur
669(1)
Reptiles: Origin of Scales and Feathers Made of Keratin
670(2)
Parental Care
672(1)
Take-Home Messages
673(1)
32.5 The Primates and Hominins
673(7)
The Primates
673(2)
Fossil Humans
675(3)
The Out-of-Africa Hypothesis
678(1)
Have Humans Stopped Evolving?
679(1)
Chapter Review
680(2)
33 Viruses
682(20)
33.1 Why Do Biologists Study Viruses?
683(2)
Viruses Shape the Evolution of Organisms
683(1)
Viruses Cause Disease
683(1)
Current Viral Pandemics in Humans: AIDS
683(2)
33.2 How Do Biologists Study Viruses?
685(9)
Analyzing Morphological Traits
686(1)
Analyzing the Genetic Material
686(1)
Analyzing the Phases of Replicative Growth
687(6)
Analyzing How Viruses Coexist with Host Cells
693(1)
33.3 What Themes Occur in the Diversification of Viruses?
694(2)
Where Did Viruses Come From?
694(1)
Emerging Viruses, Emerging Diseases
694(2)
33.4 Key Lineages of Viruses
696(4)
Chapter Review
700(2)
Big Picture: Diversity of Life
702(2)
Unit 6 How Plants Work 704(114)
34 Plant Form and Function
704(23)
34.1 Plant Form: Themes with Many Variations
705(8)
The Importance of Surface Area/Volume Relationships
706(1)
The Root System
707(1)
The Shoot System
708(2)
The Leaf
710(3)
34.2 Plant Cells and Tissue Systems
713(5)
The Dermal Tissue System
714(1)
The Ground Tissue System
714(2)
The Vascular Tissue System
716(2)
34.3 Primary Growth Extends the Plant Body
718(3)
How Do Apical Meristems Produce the Primary Plant Body?
718(2)
How Is the Primary Root System Organized?
720(1)
How Is the Primary Shoot System Organized?
720(1)
34.4 Secondary Growth Widens Shoots and Roots
721(4)
What Is a Cambium?
721(1)
How Does a Cambium Initiate Secondary Growth?
722(1)
What Do Vascular Cambia Produce?
723(1)
What Do Cork Cambia Produce?
724(1)
The Structure of Tree Trunks
724(1)
Chapter Review
725(2)
35 Water and Sugar Transport in Plants
727(20)
35.1 Water Potential and Water Movement
728(4)
What Is Water Potential?
728(1)
What Factors Affect Water Potential?
728(1)
Working with Water Potentials
729(1)
Water Potentials in Soils, Plants, and the Atmosphere
730(2)
35.2 How Does Water Move from Roots to Shoots?
732(5)
Movement of Water and Solutes into the Root
732(1)
Water Movement via Root Pressure
733(1)
Water Movement via Capillary Action
734(1)
The Cohesion-Tension Theory
734(3)
35.3 Plant Features That Reduce Water Loss
737(1)
Limiting Water Loss
737(1)
Obtaining Carbon Dioxide under Water Stress
738(1)
35.4 Translocation of Sugars
738(7)
Tracing Connections between Sources and Sinks
738(2)
The Anatomy of Phloem
740(1)
The Pressure-Flow Hypothesis
740(1)
Phloem Loading
741(3)
Phloem Unloading
744(1)
Chapter Review
745(2)
36 Plant Nutrition
747(18)
36.1 Nutritional Requirements of Plants
748(3)
Which Nutrients Are Essential?
748(2)
What Happens When Key Nutrients Are in Short Supply?
750(1)
36.2 Soil: A Dynamic Mixture of Living and Nonliving Components
751(3)
The Importance of Soil Conservation
751(1)
What Factors Affect Nutrient Availability?
752(2)
36.3 Nutrient Uptake
754(4)
Mechanisms of Nutrient Uptake
754(2)
Mechanisms of Ion Exclusion
756(2)
36.4 Nitrogen Fixation
758(2)
The Role of Symbiotic Bacteria
759(1)
How Do Nitrogen-Fixing Bacteria Infect Plant Roots?
759(1)
36.5 Nutritional Adaptations of Plants
760(2)
Parasitic Plants
760(1)
Epiphytic Plants
761(1)
Carnivorous Plants
762(1)
Chapter Review
762(3)
37 Plant Sensory Systems, Signals, and Responses
765(28)
37.1 Information Processing in Plants
766(2)
How Do Cells Receive and Process an External Signal?
766(1)
How Do Cells Respond to Cell-Cell Signals?
766(2)
37.2 Blue Light: The Phototropic Response
768(4)
Phototropins as Blue-Light Receptors
768(1)
Auxin as the Phototropic Hormone
769(3)
37.3 Red and Far-Red Light: Germination, Stem Elongation, and Flowering
772(3)
The Red/Far-Red "Switch"
772(1)
Phytochrome Is a Red/Far-Red Receptor
772(1)
Signals That Promote Flowering
773(2)
37.4 Gravity: The Gravitropic Response
775(2)
The Statolith Hypothesis
775(1)
Auxin as the Gravitropic Signal
776(1)
37.5 How Do Plants Respond to Wind and Touch?
777(1)
Changes in Growth Patterns
777(1)
Movement Responses
777(1)
37.6 Youth, Maturity, and Aging: The Growth Responses
778(8)
Auxin and Apical Dominance
778(1)
Cytokinins and Cell Division
779(1)
Gibberellins and ABA: Growth and Dormancy
779(3)
Brassinosteroids and Body Size
782(1)
Ethylene and Senescence
783(1)
An Overview of Plant Growth Regulators
784(2)
37.7 Pathogens and Herbivores: The Defense Responses
786(4)
How Do Plants Sense and Respond to Pathogens?
786(2)
How Do Plants Sense and Respond to Herbivore Attack?
788(2)
Chapter Review
790(3)
38 Plant Reproduction and Development
793(23)
38.1 An Introduction to Plant Reproduction
794(2)
Asexual Reproduction
794(1)
Sexual Reproduction and the Plant Life Cycle
795(1)
38.2 Reproductive Structures
796(3)
The General Structure of the Flower
796(1)
How Are Female Gametophytes Produced?
797(1)
How Are Male Gametophytes Produced?
798(1)
38.3 Pollination and Fertilization
799(3)
Pollination
799(3)
Fertilization
802(1)
38.4 Seeds and Fruits
802(5)
The Role of Drying in Seed Maturation
803(1)
Fruit Development and Seed Dispersal
803(2)
Seed Dormancy
805(1)
Seed Germination
806(1)
38.5 Embryogenesis and Vegetative Development
807(3)
Embryogenesis
807(1)
Meristem Formation
808(1)
Which Genes Determine Body Axes in the Plant Embryo?
809(1)
Which Genes Determine Leaf Structure and Shape?
810(1)
38.6 Reproductive Development
810(3)
The Floral Meristem and the Flower
811(1)
The Genetic Control of Flower Structures
811(2)
Chapter Review
813(3)
Big Picture: Plant and Animal Form and Function
816(2)
Unit 7 How Animals Work 818(211)
39 Animal Form and Function
818(18)
39.1 Form, Function, and Adaptation
819(2)
The Role of Fitness Trade-Offs
819(2)
Adaptation and Acclimatization
821(1)
39.2 Tissues, Organs, and Systems: How Does Structure Correlate with Function?
821(5)
Structure-Function Relationships at the Molecular and Cellular Levels
822(1)
Tissues Are Groups of Cells That Function as a Unit
822(3)
Organs and Organ Systems
825(1)
39.3 How Does Body Size Affect Animal Physiology?
826(3)
Surface Area/Volume Relationships: Theory
826(1)
Surface Area/Volume Relationships: Data
827(1)
Adaptations That Increase Surface Area
828(1)
39.4 Homeostasis
829(2)
Homeostasis: General Principles
829(1)
The Role of Regulation and Feedback
830(1)
39.5 Thermoregulation: A Closer Look
831(3)
Mechanisms of Heat Exchange
831(1)
Thermoregulatory Strategies
832(1)
Comparing Endothermy and Ectothermy
832(1)
Countercurrent Heat Exchangers
833(1)
Chapter Review
834(2)
40 Water and Electrolyte Balance in Animals
836(19)
40.1 Osmoregulation and Excretion
837(3)
What Is Osmotic Stress?
837(1)
Osmotic Stress in Seawater, in Freshwater, and on Land
837(2)
How Do Electrolytes and Water Move across Cell Membranes?
839(1)
Types of Nitrogenous Wastes: Impact on Water Balance
839(1)
40.2 Water and Electrolyte Balance in Marine Fishes
840(1)
Osmoconformation versus Osmoregulation in Marine Fishes
840(1)
How Do Sharks Excrete Salt?
840(1)
40.3 Water and Electrolyte Balance in Freshwater Fishes
841(1)
How Do Freshwater Fishes Osmoregulate?
841(1)
40.4 Water and Electrolyte Balance in Terrestrial Insects
842(2)
How Do Insects Minimize Water Loss from the Body Surface?
843(1)
40.5 Water and Electrolyte Balance in Terrestrial Vertebrates
844(8)
The Structure of the Mammalian Kidney
844(1)
The Function of the Mammalian Kidney: An Overview
845(1)
Filtration: The Renal Corpuscle
846(1)
Reabsorption: The Proximal Tubule
846(1)
Creating an Osmotic Gradient: The Loop of Henle
847(3)
Regulating Water and Electrolyte Balance: The Distal Tubule and Collecting Duct
850(1)
Urine Formation in Nonmammalian Vertebrates
851(1)
Chapter Review
852(3)
41 Animal Nutrition
855(19)
41.1 Nutritional Requirements
856(2)
41.2 Capturing Food: The Structure and Function of Mouthparts
858(1)
Mouthparts as Adaptations
858(1)
A Case Study: The Cichlid Throat Jaw
858(1)
41.3 How Are Nutrients Digested and Absorbed?
859(10)
An Introduction to the Digestive Tract
859(1)
An Overview of Digestive Processes
860(1)
The Mouth and Esophagus
861(1)
The Stomach
862(2)
The Small Intestine
864(4)
The Large Intestine
868(1)
41.4 Nutritional Homeostasis-Glucose as a Case Study
869(2)
The Discovery of Insulin
869(1)
Insulin's Role in Homeostasis
870(1)
Diabetes Mellitus Has Two Forms
870(1)
The Type 2 Diabetes Mellitus Epidemic
870(1)
Chapter Review
871(3)
42 Gas Exchange and Circulation
874(25)
42.1 The Respiratory and Circulatory Systems
875(1)
42.2 Air and Water as Respiratory Media
875(2)
How Do Oxygen and Carbon Dioxide Behave in Air?
875(1)
How Do Oxygen and Carbon Dioxide Behave in Water?
876(1)
42.3 Organs of Gas Exchange
877(7)
Physical Parameters: The Law of Diffusion
877(1)
How Do Gills Work?
878(1)
How Do Insect Tracheae Work?
879(2)
How Do Vertebrate Lungs Work?
881(2)
Homeostatic Control of Ventilation
883(1)
42.4 How Are Oxygen and Carbon Dioxide Transported in Blood?
884(4)
Structure and Function of Hemoglobin
884(3)
CO
O2
Transport and the Buffering of Blood pH
887(1)
42.5 Circulation
888(9)
What Is an Open Circulatory System?
889(1)
What Is a Closed Circulatory System?
889(2)
How Does the Heart Work?
891(4)
Patterns in Blood Pressure and Blood Flow
895(2)
Chapter Review
897(2)
43 Animal Nervous Systems
899(23)
43.1 Principles of Electrical Signaling
900(4)
Types of Neurons
900(1)
The Anatomy of a Neuron
901(1)
An Introduction to Membrane Potentials
901(1)
How Is the Resting Potential Maintained?
902(1)
Using Electrodes to Measure Membrane Potentials
903(1)
What Is an Action Potential?
903(1)
43.2 Dissecting the Action Potential
904(4)
Distinct Ion Currents Are Responsible for Depolarization and Repolarization
904(1)
How Do Voltage-Gated Channels Work?
904(1)
How Is the Action Potential Propagated?
905(3)
43.3 The Synapse
908(4)
Synapse Structure and Neurotransmitter Release
908(2)
What Do Neurotransmitters Do?
910(1)
Postsynaptic Potentials
910(2)
43.4 The Vertebrate Nervous System
912(7)
What Does the Peripheral Nervous System Do?
912(1)
Functional Anatomy of the CNS
913(4)
How Do Learning and Memory Work?
917(2)
Chapter Review
919(3)
44 Animal Sensory Systems
922(20)
44.1 How Do Sensory Organs Convey Information to the Brain?
923(1)
Sensory Transduction
923(1)
Transmitting Information to the Brain
924(1)
44.2 Mechanoreception: Sensing Pressure Changes
924(5)
How Do Sensory Cells Respond to Sound Waves and Other Forms of Pressure?
924(1)
Hearing: The Mammalian Ear
925(3)
The Lateral Line System in Fishes and Amphibians
928(1)
44.3 Photoreception: Sensing Light
929(5)
The Insect Eye
929(1)
The Vertebrate Eye
930(4)
44.4 Chemoreception: Sensing Chemicals
934(3)
Taste: Detecting Molecules in the Mouth
934(1)
Olfaction: Detecting Molecules in the Air
935(2)
44.5 Other Sensory Systems
937(2)
Thermoreception: Sensing Temperature
937(1)
Electroreception: Sensing Electric Fields
938(1)
Magnetoreception: Sensing Magnetic Fields
939(1)
Chapter Review
939(3)
45 Animal Movement
942(19)
45.1 How Do Muscles Contract?
943(4)
Early Muscle Experiments
943(1)
The Sliding-Filament Model
943(1)
How Do Actin and Myosin Interact?
944(2)
How Do Neurons Initiate Contraction?
946(1)
45.2 Muscle Tissues
947(3)
Smooth Muscle
947(1)
Cardiac Muscle
948(1)
Skeletal Muscle
948(2)
45.3 Skeletal Systems
950(4)
Hydrostatic Skeletons
951(1)
Endoskeletons
952(1)
Exoskeletons
953(1)
45.4 Locomotion
954(4)
How Do Biologists Study Locomotion?
954(3)
Size Matters
957(1)
Chapter Review
958(3)
46 Chemical Signals in Animals
961(20)
46.1 Cell-to-Cell Signaling: An Overview
962(4)
Major Categories of Chemical Signals
962(1)
Hormone Signaling Pathways
963(1)
What Makes Up the Endocrine System?
964(1)
How Do Researchers Identify a Hormone?
965(1)
A Breakthrough in Measuring Hormone Levels
965(1)
46.2 How Do Hormones Act on Target Cells?
966(5)
Hormone Concentrations Are Low, but Their Effects Are Large
966(1)
Three Chemical Classes of Hormones
967(1)
Steroid Hormones Bind to Intracellular Receptors
967(1)
Polypeptide Hormones Bind to Receptors on the Plasma Membrane
968(2)
Why Do Different Target Cells Respond in Different Ways?
970(1)
46.3 What Do Hormones Do?
971(5)
How Do Hormones Direct Developmental Processes?
971(2)
How Do Hormones Coordinate Responses to Stressors?
973(2)
How Are Hormones Involved in Homeostasis?
975(1)
46.4 How Is the Production of Hormones Regulated?
976(2)
The Hypothalamus and Pituitary Gland
976(2)
Control of Epinephrine by Sympathetic Nerves
978(1)
Chapter Review
978(3)
47 Animal Reproduction and Development
981(27)
47.1 Asexual and Sexual Reproduction
982(4)
How Does Asexual Reproduction Occur?
982(1)
Switching Reproductive Modes: A Case History
982(2)
Mechanisms of Sexual Reproduction: Gametogenesis
984(2)
47.2 Reproductive Structures and Their Functions
986(3)
The Male Reproductive System
986(1)
The Female Reproductive System
987(2)
47.3 Fertilization and Egg Development
989(5)
External Fertilization
989(1)
Internal Fertilization
989(2)
The Cell Biology of Fertilization
991(1)
Why Do Some Females Lay Eggs While Others Give Birth?
992(2)
47.4 Embryonic Development
994(5)
Cleavage
994(1)
Gastrulation
995(1)
Organogenesis
996(3)
47.5 The Role of Sex Hormones in Mammalian Reproduction
999(3)
Which Hormones Control Puberty?
999(1)
Which Hormones Control the Menstrual Cycle in Humans?
1000(2)
47.6 Pregnancy and Birth in Mammals
1002(3)
Gestation and Development in Marsupials
1003(1)
Major Events during Human Pregnancy
1003(1)
How Does the Mother Nourish the Fetus?
1004(1)
Birth
1005(1)
Chapter Review
1005(3)
48 The Immune System in Animals
1008(21)
48.1 Innate Immunity
1009(4)
Barriers to Entry
1009(1)
The Innate Immune Response
1010(3)
48.2 Adaptive Immunity: Recognition
1013(5)
An Introduction to Lymphocytes
1013(1)
Lymphocytes Recognize a Diverse Array of Antigens
1014(3)
How Does the Immune System Distinguish Self from Nonself?
1017(1)
48.3 Adaptive Immunity: Activation
1018(4)
The Clonal Selection Theory
1018(1)
T-Cell Activation
1019(1)
B-Cell Activation and Antibody Secretion
1020(2)
48.4 Adaptive Immunity: Response and Memory
1022(3)
How Are Extracellular Pathogens Eliminated?
1022(1)
How Are Intracellular Pathogens Eliminated?
1023(1)
Why Does the Immune System Reject Foreign Tissues and Organs?
1024(1)
Responding to Future Infections: Immunological Memory
1024(1)
48.5 What Happens When the Immune System Doesn't Work Correctly?
1025(2)
Allergies
1026(1)
Autoimmune Diseases
1026(1)
Immunodeficiency Diseases
1026(1)
Chapter Review
1027(2)
Unit 8 Ecology 1029
49 An Introduction to Ecology
1029(22)
49.1 Levels of Ecological Study
1030(1)
Organismal Ecology
1030(1)
Population Ecology
1031(1)
Community Ecology
1031(1)
Ecosystem Ecology
1031(1)
Global Ecology
1031(1)
Conservation Biology Applies All Levels of Ecological Study
1031(1)
49.2 What Determines the Distribution and Abundance of Organisms?
1031(5)
Abiotic Factors
1032(1)
Biotic Factors
1032(1)
History Matters: Past Abiotic and Biotic Factors Influence Present Patterns
1033(1)
Biotic and Abiotic Factors Interact
1034(2)
49.3 Climate Patterns
1036(3)
Why Are the Tropics Warm and the Poles Cold?
1036(1)
Why Are the Tropics Wet?
1036(1)
What Causes Seasonality in Weather?
1036(2)
What Regional Effects Do Mountains and Oceans Have on Climate?
1038(1)
49.4 Types of Terrestrial Biomes
1039(4)
Natural Biomes
1039(1)
Anthropogenic Biomes
1040(2)
How Will Global Climate Change Affect Terrestrial Biomes?
1042(1)
49.5 Types of Aquatic Biomes
1043(5)
Salinity
1043(1)
Water Depth and Sunlight Availability
1044(1)
Water Flow
1045(1)
Nutrient Availability
1045(3)
How Are Aquatic Biomes Affected by Humans?
1048(1)
Chapter Review
1048(3)
50 Behavioral Ecology
1051(19)
50.1 An Introduction to Behavioral Ecology
1052(2)
Proximate and Ultimate Causation
1052(1)
Types of Behavior: An Overview
1053(1)
50.2 Choosing What, How, and When to Eat
1054(2)
Proximate Causes: Foraging Alleles in Drosophila melanogaster
1054(1)
Ultimate Causes: Optimal Foraging
1054(2)
50.3 Choosing a Mate
1056(2)
Proximate Causes: How Is Sexual Activity Triggered in Anolis Lizards?
1056(1)
Ultimate Causes: Sexual Selection
1057(1)
50.4 Choosing a Place to Live
1058(3)
Proximate Causes: How Do Animals Navigate?
1058(2)
Ultimate Causes: Why Do Animals Migrate?
1060(1)
50.5 Communicating with Others
1061(3)
Proximate Causes: How Do Honeybees Communicate?
1061(1)
Ultimate Causes: Why Do Honeybees Communicate the Way They Do?
1062(1)
When Is Communication Honest or Deceitful?
1063(1)
50.6 Cooperating with Others
1064(4)
Kin Selection
1064(2)
Quantitative Methods 50.1 Calculating the Coefficient of Relatedness
1065(1)
Manipulation
1066(1)
Reciprocal Altruism
1067(1)
Cooperation and Mutualism
1067(1)
Individuals Do Not Act for the Good of the Species
1067(1)
Chapter Review
1068(2)
51 Population Ecology
1070(22)
51.1 Distribution and Abundance
1071(1)
Geographic Distribution
1071(1)
Sampling Methods
1072(1)
51.2 Demography
1072(4)
Life Tables
1072(3)
Quantitative Methods 51.1 Mark-Recapture Studies
1073(2)
The Role of Life History
1075(1)
Quantitative Methods 51.2 Using Life Tables to Calculate Population Growth Rates
1075(1)
51.3 Population Growth
1076(5)
Exponential Growth
1077(2)
Quantitative Methods 51.3 Using Growth Models to Predict Population Growth
1078(1)
Logistic Growth
1079(1)
What Factors Limit Population Size?
1080(1)
51.4 Population Dynamics
1081(3)
Why Do Some Populations Cycle?
1081(2)
How Do Metapopulations Change through Time?
1083(1)
51.5 Human Population Growth
1084(3)
Age Structure in Human Populations
1084(1)
Analyzing Change in the Growth Rate of Human Populations
1085(2)
51.6 How Can Population Ecology Help Conserve Biodiversity?
1087(3)
Using Life-Table Data
1087(1)
Preserving Metapopulations
1088(2)
Chapter Review
1090(2)
52 Community Ecology
1092(24)
52.1 Species Interactions
1093(10)
Commensalism
1093(1)
Competition
1094(4)
Consumption
1098(3)
Mutualism
1101(2)
52.2 Community Structure
1103(4)
Why Are Some Species More Important than Others in Structuring Communities?
1104(1)
How Predictable Are Communities?
1105(2)
52.3 Community Dynamics
1107(4)
Disturbance and Change in Ecological Communities
1107(1)
Succession: The Development of Communities after Disturbance
1108(3)
52.4 Patterns in Species Richness
1111(3)
Quantitative Methods 52.1 Measuring Species Diversity
1111(1)
Predicting Species Richness: The Theory of Island Biogeography
1112(1)
Global Patterns in Species Richness
1113(1)
Chapter Review
1114(2)
53 Ecosystems and Global Ecology
1116(23)
53.1 How Does Energy Flow through Ecosystems?
1117(6)
How Efficient Are Autotrophs at Capturing Solar Energy?
1117(1)
What Happens to the Biomass of Autotrophs?
1118(1)
Energy Transfer between Trophic Levels
1119(2)
Global Patterns in Productivity
1121(2)
53.2 How Do Nutrients Cycle through Ecosystems?
1123(6)
Nutrient Cycling within Ecosystems
1123(2)
Global Biogeochemical Cycles
1125(4)
53.3 Global Climate Change
1129(8)
What Is the Cause of Global Climate Change?
1130(1)
How Much Will the Climate Change?
1131(2)
Biological Effects of Climate Change
1133(2)
Consequences to Net Primary Productivity
1135(2)
Chapter Review
1137(2)
54 Biodiversity and Conservation Biology
1139(23)
54.1 What Is Biodiversity?
1140(5)
Biodiversity Can Be Measured and Analyzed at Several Levels
1140(2)
How Many Species Are Living Today?
1142(1)
Where Is Biodiversity Highest?
1142(3)
54.2 Threats to Biodiversity
1145(7)
Multiple Interacting Threats
1145(4)
How Will These Threats Affect Future Extinction Rates?
1149(3)
Quantitative Methods 54.1 Species-Area Plots
1150(2)
54.3 Why Is Biodiversity Important?
1152(4)
Biological Benefits of Biodiversity
1152(2)
Ecosystem Services: Economic and Social Benefits of Biodiversity and Ecosystems
1154(1)
An Ethical Dimension
1155(1)
54.4 Preserving Biodiversity and Ecosystem Function
1156(3)
Addressing the Ultimate Causes of Loss
1156(1)
Conservation Strategies to Preserve Genetic Diversity, Species, and Ecosystem Function
1157(2)
Take-Home Message
1159(1)
Chapter Review
1159(3)
Big Picture: Ecology
1162
Appendix A Answers A:1
Appendix B Periodic Table of Elements B:1
Glossary G:1
Credits Cr:1
Index I:1