Muutke küpsiste eelistusi

Biomedical Imaging Instrumentation: Applications in Tissue, Cellular and Molecular Diagnostics [Pehme köide]

Edited by (Director General R&D and KIIT University CEO, KIIT-Technology Business Incubator, Bhubaneswar, India), Edited by , Edited by (Assistant Professor, KIIT School of Biotechnology; Head, Bio-innovations, KIIT Technology Business Incubator, KIIT Deemed to Be Uni)
  • Formaat: Paperback / softback, 238 pages, kõrgus x laius: 235x191 mm, kaal: 500 g, 20 illustrations (10 in full color); Illustrations
  • Sari: Primers in Biomedical Imaging Devices and Systems
  • Ilmumisaeg: 06-Dec-2021
  • Kirjastus: Academic Press Inc
  • ISBN-10: 0323856500
  • ISBN-13: 9780323856508
Teised raamatud teemal:
Biomedical Imaging Instrumentation: Applications in Tissue, Cellular and Molecular DiagnosticsSuurem pilt
  • Formaat: Paperback / softback, 238 pages, kõrgus x laius: 235x191 mm, kaal: 500 g, 20 illustrations (10 in full color); Illustrations
  • Sari: Primers in Biomedical Imaging Devices and Systems
  • Ilmumisaeg: 06-Dec-2021
  • Kirjastus: Academic Press Inc
  • ISBN-10: 0323856500
  • ISBN-13: 9780323856508
Teised raamatud teemal:
Püsilink: https://www.kriso.ee/db/9780323856508.html
Märksõnad:

Primers in Biomedical Imaging Devices and Systems is a 10-volume series which covers the key principles, background, and advancements in biomedicine-related technologies. It explores the essential fundamental techniques required to analyze and process signals and images for diagnosis, scientific discovery, and medical applications.

The volumes in this book series cover a wide range of interdisciplinary areas, combining foundational content with practical case studies to demonstrate the applications of the technology in real-world situations. The series considers various medical devices, electronics, circuits, sensors, and algorithms. Several applications ranging from the basic biological science to clinical practice are included to facilitate ongoing research.

This book series covers a wide range of interdisciplinary applications including use in imaging modalities, nuclear medicine, computed tomographic systems, x-ray systems, magnetic resonance imaging, ultrasound, and virtual reality. The wide scope of technology considered in this series makes it an ideal source for researchers, graduate students, engineers and medical practitioners involved with medical device development and application in the healthcare industry.

Biomedical Imaging Instrumentation: Applications in Tissue, Cellular and Molecular Diagnostics

provides foundational information about imaging modalities, reconstruction and processing and their applications. Content includes coverage of Electrical Impedance Tomography, Fluorescence and Raman imaging, CARS microscopy, sonography, and acoustic microscopy. Each chapter is divided into: Definitions, Summaries, Detailed methods / protocols, Applications, Recent developments, Calculations / worked examples. This book is ideal for supporting learning, and will be useful for students and early career researchers in fields such as medical imaging and biomedical instrumentation.

  • A basic, fundamental, easy to understand introduction to medical imaging techniques
  • Insights into the limitations of each technology and innovations that are happening related to that technology
  • Each technique provides a report, and this book explains these reports in an accessible and easy to understand way
Contributors xiii
Preface xvii
Chapter 1 Biomedical techniques in cellular and molecular diagnostics: Journey so far and the way forward
1(12)
Gajraj Singh Kushwaha
Neel Sarovar Bhavesh
Namrata Misra
Mrutyunjay Suar
1.1 Biomedical imaging technology
1(9)
1.1.1 CTscan
2(1)
1.1.2 Ultrasound imaging
3(1)
1.1.3 Magnetic resonance imaging
4(1)
1.1.4 Positron emission tomography scans
5(1)
1.1.5 Single-photon emission computerized tomography
6(1)
1.1.6 Mammography
6(1)
1.1.7 Hyperspectral imaging
7(1)
1.1.8 Photoacoustic (PA) imaging
8(1)
1.1.9 Near-infrared spectroscopy (NIRS)
8(1)
1.1.10 Microscopy imaging
9(1)
1.2 Way forward
10(3)
References
10(3)
Chapter 2 Role of CT scan in medical and dental imaging
13(20)
Lora Mishra
Rini Behera
Satabdi Pattanaik
Naomi Ranjan Singh
2.1 Introduction to computed tomography
13(1)
2.2 Benefits and uses of CT scan
14(1)
2.3 Issues regarding CT scan
14(1)
2.4 Technical parameters and clinical applications
15(3)
2.4.1 Head and neck
16(1)
2.4.2 Lung
16(1)
2.4.3 Kidney
16(1)
2.4.4 Liver
16(1)
2.4.5 Pancreas
16(1)
2.4.6 Vascular system
17(1)
2.4.7 Heart
17(1)
2.4.8 Bone
17(1)
2.5 Advancement in CT scans
18(2)
2.5.1 Extreme MDCT
18(1)
2.5.2 Iterative reconstruction
18(1)
2.5.3 Dual-energy CT
19(1)
2.5.4 Phase-contrast CT
20(1)
2.5.5 Cone beam CT
20(1)
2.6 Application of CBCT in dentistry
20(7)
2.6.1 CBCT in dental implantology
20(2)
2.6.2 CBCT in oral and maxillofacial surgery
22(1)
2.6.3 CBCT in endodontics
23(2)
2.6.4 Applications in orthodontics
25(1)
2.6.5 Pediatric dentistry
25(1)
2.6.6 Periodontics
26(1)
2.6.7 Forensic dentistry
27(1)
2.7 Conclusion
27(6)
References
27(6)
Chapter 3 Ultrasonography Technology and applications in clinical radiology
33(12)
Syamantak Mookherjee
Devjani Ghosh Shrestha
Skandesh Mohan
3.1 Introduction
33(1)
3.2 Properties of sound
33(2)
3.3 Interaction between ultrasound and matter
35(3)
3.3.1 Reflection
35(1)
3.3.2 Refraction
35(2)
3.3.3 Absorption
37(1)
3.4 Fundamental technology
38(2)
3.4.1 Piezoelectricity and production of ultrasound
38(2)
3.5 Instrumentation and image formation
40(2)
3.5.1 Transmitter
40(1)
3.5.2 Beam former
40(1)
3.5.3 Transducer
40(1)
3.5.4 Receiver
41(1)
3.5.5 Image processor/scan converter
42(1)
3.5.6 Image display
42(1)
3.6 Image representation and clinical application
42(2)
3.6.1 Modes of ultrasound
42(2)
3.6.2 Elastography
44(1)
3.7 Conclusion
44(1)
Chapter 4 Magnetic resonance imaging: Basic principles and advancement in clinical and diagnostics approaches in health care
45(22)
Doniparthi Pradeep
Manoj Kumar Tembhre
Anita Singh Parihar
Chandrabhan Rao
4.1 Introduction
45(1)
4.2 Basic principles of MRI
46(2)
4.3 Components of MRI
48(3)
4.3.1 Magnet
48(2)
4.3.2 Gradient and shim coils
50(1)
4.3.3 Radiofrequency coils (RFC)
50(1)
4.3.4 Computer system
51(1)
4.4 The basic concept of image acquisition and formation in an MRI system
51(3)
4.5 Contrast agents used in MRI
54(2)
4.5.1 Magnetic susceptibility
54(1)
4.5.2 Molecular tumbling/Larmor frequency and dipole interactions: A rationale of contrast
55(1)
4.5.3 Nature of contrast agents
55(1)
4.5.4 Classification of contrast agents
55(1)
4.6 Intravenous agents
56(1)
4.7 MRI contrast agents: based on the specific area of interest
57(1)
4.7.1 Brain
57(1)
4.7.2 Spine
57(1)
4.7.3 Abdomen
57(1)
4.7.4 Blood vessels
57(1)
4.7.5 Breast imaging
57(1)
4.6.6 Safety concerns associated with the use of contrast agents
57(1)
4.8 Types of MRI and their applications
58(2)
4.8.1 Anatomic imaging
58(1)
4.8.2 Functional magnetic resonance imaging (fMRI)
58(1)
4.8.3 Diffusion tensor imaging
59(1)
4.8.4 Arterial spin labeling (ASL)
59(1)
4.8.5 Neuromelanin-sensitive MRI
60(1)
4.8.6 Quantitative susceptibility mapping
60(1)
4.9 Current clinical applications of MRI in cardiovascular diseases
60(2)
4.9.1 Assessment of left and right ventricular volumes and mass, as well as systolic function
61(1)
4.9.2 Assessment of myocardial viability and myocardial perfusion
61(1)
4.9.3 Evaluation of congenital heart disease with shunt calculation
61(1)
4.9.4 Evaluation and follow-up of valvular disease
61(1)
4.9.5 Evaluation of pericardial disease
61(1)
4.9.6 Evaluation of aortic disease
62(1)
4.9.7 Evaluation of cardiac masses
62(1)
4.9.8 Cardiomyopathies
62(1)
4.9.9 Arrhythmogenic right ventricular cardiomyopathy
62(1)
4.10 Role of MRI in diagnosis, staging, and disease evaluation in cancers
62(1)
4.11 Contraindications and limitations of MRI
63(1)
4.12 Conclusion
63(4)
References
64(3)
Chapter 5 Current update about instrumentation and utilization of PET-CT scan in oncology and human diseases
67(18)
Rohit Gundamaraju
Chandrabhan Rao
Naresh Poondla
5.1 Introduction
67(1)
5.2 PET imaging and instrumentation
68(3)
5.2.1 Principles of PET
68(1)
5.2.2 Acquisition and image reconstruction: 2D versus 3D
68(1)
5.2.3 Random correction
69(1)
5.2.4 Attenuation correction
69(1)
5.2.5 Scatter correction
70(1)
5.2.6 Image reconstruction methods
70(1)
5.2.7 The need for PET screening in diverse cancers
70(1)
5.3 Clinical significances of PET in cancer
71(7)
5.3.1 Clinical endorsement by PET-CT
72(3)
5.3.2 Detailed staging with the help of PET
75(1)
5.3.3 PET-CT as support therapy
76(2)
5.4 Role of PET in the diagnosis of human diseases other than cancer
78(1)
5.5 Conclusion
78(7)
References
79(6)
Chapter 6 Revolutionizing medical diagnosis with SPECT imaging: Clinical applications of a nuclear imaging technology
85(20)
Mena Asha Krishnan
Amulya Cherukumudi
Sibi Oommen
Sumeet Suresh Malapure
Venkatesh Chelvam
6.1 Introduction
85(1)
6.1.1 Historical origin and development of single photon emission tomography
85(1)
6.2 Components and working of SPECT imaging device
86(4)
6.3 SPECT applications
90(5)
6.3.1 SPECT/CT for benign conditions of the bone
90(1)
6.3.2 SPECT/CT in neuroendocrine neoplasms
90(3)
6.3.3 Radionuclide bone imaging for staging malignant metastases
93(2)
6.4 Targeted imaging of prostate cancer with radioligands
95(2)
6.5 SPECT imaging using 67ga-citrate SPECT/CT in lymphoma
97(1)
6.6 SPECT imaging: nononcologic diseases
98(1)
6.7 Conclusion
99(6)
References
100(5)
Chapter 7 Mammography--sentinel of breast cancer management
105(10)
Joseph Thomas
Amulya Cherukumudi
V. Pramod
7.1 Introduction
105(1)
7.2 Evolution of mammography
106(1)
7.3 Dissecting the mammography machine
107(2)
7.4 How a mammogram is captured
109(1)
7.5 Deciphering a mammogram
109(2)
7.6 Limitations
111(1)
7.7 Recent advances in mammography
111(1)
7.7.1 Contrast-enhanced mammography
111(1)
7.7.2 Three-dimensional mammography
111(1)
7.7.3 Photon counting mammography
111(1)
7.7.4 Galactography
112(1)
7.8 Alternatives
112(1)
7.9 Conclusion
112(3)
References
112(3)
Chapter 8 Hyperspectral Imaging: Current and Potential Clinical Applications
115(16)
Sakir Ahmed
Prajna Anirvan
Priyanku Pratik Sharma
Manmath Kumar Das
8.1 Introduction
115(1)
8.2 Concept
115(1)
8.3 Principles
116(1)
8.4 Techniques
117(1)
8.5 Analysis
118(1)
8.6 Biomedical uses
118(1)
8.7 Use externally to the human body
119(1)
8.7.1 Monitoring of patients in critical care
119(1)
8.7.2 Diagnosis of skin cancers
119(1)
8.7.3 Diagnosis and monitoring of other skin lesions
119(1)
8.7.4 Screening for arthritis
120(1)
8.7.5 Screening for vascular diseases
120(1)
8.8 Use in endoscopies
120(2)
8.8.1 Upper and lower gastrointestinal endoscopy
120(1)
8.8.2 Endoscopic retrograde chonlangiopancreatogram (ERCP) and choledochoscopy
121(1)
8.8.3 Video-assisted thoracic surgery (VATS)
121(1)
8.8.4 Functional endoscopic sinus surgery and neuroendoscopy
122(1)
8.8.5 Cystoscopy
122(1)
8.9 Applications in surgery
122(3)
8.9.1 Gastrointestinal anastomoses
122(1)
8.9.2 Breast surgery
123(1)
8.9.3 Renal surgery
123(1)
8.9.4 Plastic surgery
124(1)
8.9.5 Transplant surgeries
124(1)
8.9.6 Colorectal cancer surgeries
125(1)
8.10 Applications for imaging the eye
125(1)
8.10.1 Retinal imaging
125(1)
8.11 In vitro imaging
125(1)
8.11.1 Models of wound healing
125(1)
8.11.2 HSI-based light microscopy
125(1)
8.11.3 Confocal microscopy
126(1)
8.12 Conclusion
126(5)
References
126(5)
Chapter 9 PA Imaging: A promising tool for targeted therapeutic implications in Cancer
131(30)
Samudyata C. Prabhuswamimath
9.1 Introduction
131(4)
9.1.1 Principle
132(2)
9.1.2 Breast Cancer
134(1)
9.2 Angiogenesis
135(4)
9.2.1 Vascular Endothelial Growth Factor
136(1)
9.2.2 VEGF and Permeability
137(1)
9.2.3 VEGF expression
138(1)
9.2.4 Angiopoietins
139(1)
9.3 Metastasis
139(4)
9.3.1 Epithelial to Mesenchymal Transition (EMT)
140(2)
9.3.2 Mitogen-activated protein kinase (MAPK) pathway
142(1)
9.4 Nanomedicine
143(4)
9.4.1 Gold nanomaterials
144(1)
9.4.2 Single-walled carbon nanotubes (SWCNTs)
145(1)
9.4.3 Semiconductor nanoparticles
146(1)
9.4.4 Organic nanoparticles
146(1)
9.4.5 Inorganic magnetic nanoparticles
146(1)
9.4.6 Graphene nanomaterial
147(1)
9.5 Biomedical applications of PAI in cancer
147(14)
References
149(12)
Chapter 10 Near-infrared spectroscopy: An important noninvasive and sensitive tool for point-of-care biosensing application
161(24)
Subhavna Juneja
Ranjita Ghosh Moulick
Deepak Kushwaha
Harsh A. Gandhi
Jaydeep Bhattacharya
10.1 Introduction
161(1)
10.2 Fundamentals of near-infrared spectroscopy
162(1)
10.2.1 Basic divisions in infrared region
162(1)
10.2.2 Molecular overtones and near-infrared spectra
163(1)
10.3 Instrumentation of near-infrared spectrophotometer
163(4)
10.3.1 Instrumentation
163(3)
10.3.2 Sampling techniques and measuring methods in near-infrared Spectroscopy
166(1)
10.4 Analyzing an infrared spectrum
167(2)
10.4.1 Data treatment of an infrared spectrum
168(1)
10.5 General applications of near-infrared spectroscopy
169(2)
10.5.1 Non invasive technology in clinical chemistry
170(1)
10.6 Nanomaterial-assisted near-infrared spectroscopy-based biosensing
171(14)
10.6.1 Semiconductor quantum dots (QDs)
173(2)
10.6.2 Carbon nanomaterials
175(1)
10.6.3 Plasmonic nanoparticles and nanoshells
176(1)
10.6.4 Dye encapsulating nanoparticles
177(2)
References
179(6)
Chapter 11 Advances in Microscopy and Their Applications in Biomedical Research
185(21)
Sonali Karhana
Madhusudan Bhat
Anupama Ninawe
Amit Kumar Dinda
11.1 Microscopy as an integral part of biomedical research
185(1)
11.2 Photon-based imaging
186(8)
11.2.1 Fluorescence microscopy: Working, advancements, and biomedical applications
187(3)
11.2.2 Confocal microscopy: Working, advancements, and biomedical applications
190(4)
11.3 Automated imaging workstations for optical microscopy
194(2)
11.4 Near-field scanning optical microscopy (NSOM): Principle and biomedical applications
196(1)
11.5 Electron-based imaging: electron microscopy (EM)
197(6)
11.5.1 Scanning electron microscope: Working and biomedical applications
198(3)
11.5.2 Transmission electron microscope: Working and biomedical applications
201(2)
11.6 Resolution for photon-based and electron-based microscopes
203(1)
11.7 Conclusion
204(2)
References 206(7)
Index 213
Dr. Suar is a PhD in Molecular Microbiology from University of Delhi and Postdoc at ETH Zurich from 2004-2007. In June 2007 he joined KIIT University and established the School of Biotechnology. During this short span of time, the School of Biotechnology became a centre of excellence, supported by the Department of Biotechnology, Govt of India.

Dr. Suar is involved in research related to interdisciplinary science with specialized focus on infection biology. His research group includes multidimensional researchers working on bacterial infection and development of vaccines. He is also involved in research related to nanobiotechnology focusing on development of nanomaterials for health application and understanding their toxicological aspects with different animal models.

He established KIIT Technology Business Incubator (KIIT-TBI) in 2009 as the CEO, nurturing 200+companies in the area of engineering, energy, biotechnology and allied areas. He has received several recognitions including the American Society of Microbiology (ASM) Professorship award in 2012 during a visit to UCLA, USA; GP Chatterjee memorial award during 102nd Indian Science Congress and the Future Young Technical Leaders by STARS Switzerland in 2010. He also attended the Global Entrepreneurship leadership Symposium at HAAS Business School, USA and visited UC Berkley. Namrata Misra PhD received a M.Sc. degree in Bioinformatics from IIT (BHU) Varanasi, India, and a Ph.D. degree in Biological Science from AcSIR - Academy of Scientific & Innovative Research, CSIR-IMMT. She also received National Post-Doctoral Fellowship from Science and Engineering Research Board, Department of Science & Technology, Government of India. She is currently an Assistant Professor in the Department of Biotechnology, KIIT University. She is also the Head Bio innovations at KIIT Technology Business Incubator, among other key positions. Her research focus is on study of vital metabolic pathways and in-depth sequence-structural analysis of underpinning enzymes and also vaccine development using computational approach. She has also developed several cutting-edge computations tools, databases and webservers. She has authored or coauthored more than 30 international journal publications, and book chapters. She is the principal Investigator of a grant examining the metabolic pathways of algae using system biology approach for biofuel production. She has received the prestigious Odisha Young Scientist Award-2019 by Science and Technology Department of Government of Odisha and also the Best Researcher Award for 2012 at CSIR-IMMT, Bhubaneswar. Dr. Misra has led a number of workshops and training programs on innovation and entrepreneurship across several Institutes. She regularly mentors to students, startups and many young academicians to facilitate the translation of research discovery from lab to market and product development in healthcare sector. She has also visited to University of Edinburgh -UK under the Training-SinnoLABs Managers program in 2018 under the EU Erasmus Mundus Program. Also, she was selected to attend the ENPRENDIA Training of trainers and management meeting in Santiago de Compostela, Spain in January 2020. Dr. Neel Sarovar Bhavesh is Group Leader at the International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India. His group uses an interdisciplinary approach encompassing a wide array of biophysical, biochemical and molecular biology techniques for understanding the structure and function of macromolecules with special thrust on molecular mechanism of Protein-RNA interactions. He is member of the editorial board of Nature Scientific Reports and reviews scientific manuscripts for international journals in the fields of structural biology and grant applications from various granting bodies in India. He presents regularly his research activity at international meetings and seminars.