This reference book compiles the latest literature on the genetic diversity, therapeutics, and drug resistance in protozoan parasites, with a focus on malaria parasites, Plasmodium falciparum, and P. vivex. The book covers the mechanisms of drug resistance, drug resistance detection and spread, and factors affecting drug resistance.
The present book describes the common human diseases caused by the blood infecting protozoans, diagnosis and treatment. This book compiles the latest literature on the genetic diversity, therapeutics, and drug resistance in protozoan parasites, with a focus on malaria parasites, Plasmodium falciparum, and P. vivex. It explores the association of parasite genetic makeup with drug resistance. The book covers the mechanisms of drug resistance, and its spread, and factors affecting drug resistance. The book facilitates research design and development of therapeutics against malarial parasites. The book is meant for post-graduate students of microbiology, parasitology, and medicine, as well as healthcare workers, medical practitioners, public health staff, and policymakers.
Key Features
- Describes the recent updates on how the different protozoan parasites cause human diseases
- Includes the genomics and epidemiology of important protozoan parasites like Plasmodium, Trypanosoma, Leishmania, and Toxoplasma.
- Further, it covers the role of nanotechnology in diagnosis and treatment of the diseases.
- Covers the detection of drug resistance in vitro and in vivo and Insilco tools for functional genomics.
- Throws light on the aspect of copy number variation (CNV) as a part of the adaption strategy in parasites.
- Discusses the molecular basis of antimalarial drug resistance in Plasmodium vivax.
- Reviews the factors contributing to the spread of resistance in malaria parasites.
1. Current updates on the causes of human diseases resulting from
protozoan parasites.
2. Understanding the genomics and epidemiology of common
protozoan diseases.
3. Diagnosis and treatment of protozoan diseases: an
update.
4. Nanotechnology in diagnosis and treatment of protozoan diseases.
5. The emergence and spread of drug resistance in blood infecting protozoans:
a major threat to human health.
6. Mechanism of drug resistance and treatment
failure in Leishmaniasis, trypanosomiasis, Toxoplasma gondii and Babesia.
7.
Investigation of sesquiterpene lactone endoperoxides and associated genetic
markers for drug resistance in P. falciparum.
8. Drug resistance marker for
Amino alcohols, Aminoquinolines, and antifolates in P. falciparum.
9.
Molecular basis of antimalarial drug resistance in Plasmodium sp., current
challenges and future perspectives.
10. Unmasking influential factors in
malaria drug resistance transmission.
11. Detection of resistance: assessing
in vivo and in vitro drug resistance in malaria parasite.
12. Monitoring of
Plasmodium Genetic Diversity and Drug Resistance Can Be an Effective Tool for
Malaria Elimination in Resource-Limited Endemic Regions.
Dr. M. Tabish Qidwai is an Associate Professor at SRM University, Lucknow, Uttar Pradesh, India. He has worked as a faculty member at B.B. Ambedkar Central University, Lucknow and Raja Balwant Singh College, Agra. His research interests are focused on the functional genomics, immunology, and infectious disease research. He received various prestigious awards including the Rashtriya Gaurav Award for remarkable contributions to Science and Technology, Certificate of Excellence in Science and Technology, University Gold Medal, Research Excellence Award, Teaching and Learning Innovation Award and several certificate of appreciation for significant contribution to academics. He has 13 years of teaching and research experience in genomics and immunology and infectious diseases. He has published nearly more than 50 book chapters, research articles, review articles and authored/edited 5 books. He has I10 index 25 and h index 21 and more than 1100 citations. Currently, He is supervising 5 PhD students and 3 PhD is awarded under his supervision. He is a member of many national and international scientific societies and organizations.
