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Breastfeeding and Medication 2nd edition [Pehme köide]

  • Formaat: Paperback / softback, 362 pages, kõrgus x laius: 246x174 mm, kaal: 640 g, 4 Tables, black and white; 31 Line drawings, black and white; 32 Halftones, black and white
  • Ilmumisaeg: 11-May-2018
  • Kirjastus: Routledge
  • ISBN-10: 1138298328
  • ISBN-13: 9781138298323
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  • Formaat: Paperback / softback, 362 pages, kõrgus x laius: 246x174 mm, kaal: 640 g, 4 Tables, black and white; 31 Line drawings, black and white; 32 Halftones, black and white
  • Ilmumisaeg: 11-May-2018
  • Kirjastus: Routledge
  • ISBN-10: 1138298328
  • ISBN-13: 9781138298323
Teised raamatud teemal:
Sadly, women often feel they have no alternative but to give up breastfeeding, having been prescribed or purchased medication. In many cases, however, this is unnecessary. This book outlines the evidence base for the use of medication during breastfeeding.

Breastfeeding and Medication presents a comprehensive A to Z guide to the most frequently prescribed drugs and their safety for breastfeeding mothers. Evaluating the evidence for interventions and using a simple format for quickly identifying medications that are safe or unsafe to use, it also highlights those drugs where there is inconclusive evidence. Additional contextual information makes this the most complete text for those practitioners who support and treat breastfeeding women. It:











provides an overview of the anatomy and physiology of the breast together with hormonal influences to better understand how complications, such as mastitis, arise and inform the approach to their treatment;





includes a section on conditions that affect women specifically when they are lactating where prescription of medication may be necessary;





discusses the importance of breastfeeding and its advantages, as well as its disadvantages; and





explores how to support breastfeeding mothers, and presents a counselling model approach.

This new edition contains information on more drugs and a chapter on the management of some chronic conditions which may affect breastfeeding mothers. In most cases there are options to support the mothers optimal care whilst allowing her to continue to breastfeed her baby as long as she wishes. This is a topic which raises many questions on social media, which informed the choice of conditions to consider.

This is an invaluable reference for all health practitioners and volunteers who work with, support and treat breastfeeding women, including lactation consultants, breastfeeding support workers, health visitors, GPs, practice nurses, pharmacists and midwives.
List of illustrations xii
Dedication xiv
Acknowledgements xv
Introduction
1(1)
Breastmilk is normal
1(1)
So why do more mothers not breastfeed?
2(1)
How can this book help?
2(1)
The safety of drugs in breastmilk
3(1)
Evidence for breastfeeding and the management of common conditions
3(1)
Counselling breastfeeding mothers
4(1)
Part I Breastfeeding in the wider context 5(106)
1 Breastfeeding in context
6(9)
The impact of society on breastfeeding
6(3)
Health inequalities and the promotion of breastfeeding
9(1)
Obesity and infant feeding
9(1)
Breastfeeding in public
9(1)
Influences on breastfeeding initiation
10(1)
Influence of friends and family
10(1)
Impact of education on breastfeeding initiation
11(1)
Peer support in populations where breastfeeding rates are historically low
11(1)
Difficulties experienced with breastfeeding
12(1)
Exclusive breastfeeding rates
13(2)
2 How does breastfeeding work?
15(11)
Anatomy of the lactating breast
15(2)
The areola
16(1)
Nipples
17(1)
Prolactin
17(1)
Oxytocin
18(2)
Inhibition of milk production
20(1)
Effective breastfeeding
21(1)
How can healthcare professionals support breastfeeding mothers?
22(1)
Assessing attachment and drainage of the breast
23(1)
Assessment of infant stools as an indicator of good milk transfer
23(1)
Pain on breastfeeding
24(1)
Key points
25(1)
3 Constituents of breastmilk and formula milk
26(6)
Breastmilk - a remarkable liquid
26(4)
Lactoferrin
27(1)
Oligosaccharides
28(1)
Lysozyme
29(1)
Epidermal growth factor
29(1)
Secretory immunoglobulin A
30(1)
Anti-inflammatory molecules
30(1)
Growth factors
30(1)
Bifidus factor
30(1)
Leukocytes
30(1)
So how do these factors protect the breastfed infant?
30(1)
Key points
31(1)
4 Understanding the importance of breastmilk
32(7)
The positive health benefits of breastfeeding
32(3)
Implications for the healthcare system
35(1)
Maternal beliefs about breastfeeding and its advantages
36(1)
Disadvantages of breastfeeding
36(1)
Medical disadvantages of breastfeeding
37(2)
Galactosaemia
37(1)
Maple syrup urine disease
38(1)
Phenylketonuria
38(1)
5 Treating conditions related to breastfeeding
39(22)
Conditions affecting the breastfeeding mother
40(6)
Engorgement
40(1)
Mastitis
40(3)
Post-partum haemorrhage
43(1)
Thromboembolism
43(1)
Raynaud's phenomenon
43(3)
Vasospasm 4S
Conditions affecting the baby
46(6)
Colic
46(1)
Cow's milk protein allergy
47(1)
Lactose intolerance
48(1)
Tongue tie
49(1)
Prematurity
50(1)
Jaundice
51(1)
Conditions that may affect the mother and baby during breastfeeding
52(2)
Oral thrush
52(2)
Medication for women who may become pregnant
54(1)
Pre-conceptual use of medication
54(1)
Pre-conceptual nutrition
54(3)
Folic acid
55(1)
Vitamin D supplements
55(2)
Obesity
57(1)
Smoking
57(1)
Vaping (electronic cigarettes)
58(1)
Alcohol
59(1)
Substance misuse
59(1)
Key points
60(1)
6 Decision-making on the safety of drugs in breastmilk
61(13)
The dilemma of prescribing
62(1)
Assessment of the transfer of drugs in breastmilk
62(1)
Pharmacokinetic data on the transfer of drugs into breastmilk
63(2)
Factors influencing drug transfer into breastmilk
65(5)
The extent of plasma protein binding of the drug
65(1)
Milk-plasma ratio
65(1)
Oral bio-availability
65(1)
First-pass metabolism
65(1)
Drug half-life
66(1)
The size of the drug molecule
66(1)
Peak plasma level
66(1)
Available data
67(1)
Fat solubility
68(1)
Immaturity of the hepatic and renal function of infants
68(1)
Breastmilk production
68(1)
In utero exposure
68(1)
Maturity of the baby
69(1)
Age of the baby and volume of milk consumed
69(1)
Possible side effects for the baby
69(1)
Therapeutic range
69(1)
Duration of exposure to the drug
70(1)
Relative infant dose
70(1)
Summary of points to determine when a drug is likely to be safe for use during breastfeeding
70(1)
Limitations of the literature on transfer of drugs into breastmilk
70(1)
Practical application of pharmacological data
71(2)
Key points
73(1)
7 Professional responsibility and counselling
74(18)
The dilemma of taking prescription drugs during breastfeeding
74(1)
How do mothers perceive the dilemma of drugs during breastfeeding?
75(1)
The polarity map
76(4)
Involving the parents in decision-making
80(3)
Information on the use of medication from the mother's viewpoint
83(1)
Professional decisions and liability
84(1)
Phrasing of information to parents
85(1)
Counselling skills
85(2)
How is counselling different from medical advice?
87(4)
Scenarios
87(4)
Key points
91(1)
8 Chronic diseases and medication in the breastfeeding mother
92(19)
Post-natal depression
92(2)
Anxiety
94(1)
Asthma
95(1)
Polycystic Ovary Syndrome (PCOS)
96(2)
Obsessional Compulsive Disorder (OCD)
98(1)
Hypertension
98(1)
Systemic lupus erythematosus (lupus)
99(1)
Sjogren's syndrome
100(1)
Multiple Sclerosis (MS)
101(2)
Fibromyalgia
103(2)
Inflammatory bowel disease (IBD)
105(2)
Diabetes
107(1)
Ectopic pregnancy
108(1)
Medical management of miscarriage
109(1)
Termination of pregnancy
109(1)
Hyperemesis/morning sickness
109(1)
Migraine
110(1)
Part II The safety of drugs in breastmilk 111(216)
9 Information on level of drugs into breastmilk
112(215)
Sources used to compile this information
113(3)
LactMed
114(1)
Medications and Mothers' Milk
114(1)
Motherisk
114(1)
The British National Formulary (BNF)
115(1)
The British National Formulary for Children (BNFC)
115(1)
Gastrointestinal system
116(24)
Antacids
116(1)
Alginates
117(1)
Anti-spasmodics
117(3)
H2 antagonists
120(2)
Proton pump inhibitors (PPIs)
122(3)
Anti-diarrhoea medication
125(2)
Inflammatory bowel disease (IBD)
127(5)
Monoclonal antibodies
132(3)
Laxatives
135(3)
Haemorrhoidal preparations
138(1)
Anal fissures
138(2)
Cardiovascular system
140(22)
Diuretics
140(2)
ACE inhibitors
142(4)
Beta blockers
146(4)
Angiotensin II receptor antagonists
150(2)
Calcium channel blockers
152(2)
Alpha blockers
154(1)
Anti-coagulants
155(3)
The novel (non-Vitamin K antagonist) oral anticoagulants (NO AC)
158(1)
Anti-platelet agents
159(2)
Lipid-regulating drugs
161(1)
Respiratory system
162(14)
Bronchodilators
163(1)
Long-acting beta2 agonists
164(1)
Corticosteroids
165(2)
Leukotriene receptor antagonists
167(1)
Anti-histamines
168(5)
Mucolytics
173(1)
Cough preparations
173(1)
Nasal decongestants
174(2)
Centrally acting drugs
176(66)
Hypnotics
176(3)
Anxiolytics
179(3)
Anti-psychotics
182(9)
Drugs to treat bipolar disorder
191(2)
Anti-depressants
193(3)
Selective serotonin re-uptake inhibitors (SSRIs)
196(6)
Serotonin and noradrenaline re-uptake inhibitors
202(1)
Alpha 2-adrenoreceptor antagonist
203(1)
Anti-obesity drugs
204(1)
Drugs used to treat nausea and vertigo
205(5)
Analgesics
210(5)
Opiate analgesics
215(4)
Migraines
219(2)
Epilepsy
221(8)
Drugs of abuse
229(6)
Substance dependence
235(4)
Nicotine replacement therapy
239(2)
Cigarettes and smoking
241(1)
Infections
242(29)
Antibiotics
242(18)
Antifungals
260(4)
Antivirals
264(2)
Neuraminidase inhibitors to treat influenza (H1N1/H5N1)
266(2)
Malarial prophylaxis
268(3)
Anthelmintics
271(1)
Endocrine system
271(6)
Diabetes
271(3)
Thyroid diseases
274(3)
Obstetric conditions
277(16)
Contraception
277(1)
Parenteral progestogen-only contraceptives
277(1)
Oral progestogen-only contraceptive pills (POPS)
278(1)
Intrauterine progestogen-only contraceptives
278(1)
Combined oral contraceptive (COC)
278(1)
Emergency hormonal contraception (EFIC)
279(1)
Suppression of lactation
280(3)
Lactation enhancement
283(6)
Drugs used to induce or augment labour
289(1)
Medical termination of pregnancy
290(2)
Ectopic pregnancy
292(1)
Malignant diseases
293(1)
Nutrition and blood
293(5)
Vitamins and tonics
293(5)
Drugs used to treat musculoskeletal and joint pains
298(4)
Non-steroidal anti-inflammatories
298(3)
Rheumatic disease-suppressing drugs
301(1)
Eye preparations
302(1)
Ear drops
303(1)
Nasal drops
304(1)
Dental treatment
304(2)
Skin
306(6)
Topical creams
306(1)
Emollients
307(1)
Bath preparations
307(1)
Topical corticosteroids
307(1)
Eczema
308(1)
Psoriasis
308(1)
Acne
308(1)
Warts and verrucas
309(1)
Sunscreens
309(1)
Topical antibacterials, antifungals and antivirals
309(1)
Head lice treatment
310(2)
Vaccines
312(8)
Anaesthetics
320(4)
General anaesthetics
320(4)
Local anaesthetics
324(1)
Homeopathic remedies
324(1)
Caffeine
325(2)
Conclusion 327(3)
Appendix 330(2)
References 332(9)
Index 341
Wendy Jones is a pharmacist, with over 25 years of experience as a breastfeeding support worker for The Breastfeeding Network (BfN). She runs the BfN Drugs in Breastmilk Service and has presented widely to healthcare professionals, volunteers and mothers on this subject. She qualified as an independent pharmacist prescriber but is now retired.