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Broca-Wernicke Doctrine: A Historical and Clinical Perspective on Localization of Language Functions Softcover reprint of the original 1st ed. 2017 [Pehme köide]

  • Formaat: Paperback / softback, 306 pages, kõrgus x laius: 235x155 mm, kaal: 670 g, 38 Illustrations, color; 73 Illustrations, black and white; XVII, 306 p. 111 illus., 38 illus. in color., 1 Paperback / softback
  • Ilmumisaeg: 12-Sep-2018
  • Kirjastus: Springer International Publishing AG
  • ISBN-10: 3319854402
  • ISBN-13: 9783319854403
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  • Formaat: Paperback / softback, 306 pages, kõrgus x laius: 235x155 mm, kaal: 670 g, 38 Illustrations, color; 73 Illustrations, black and white; XVII, 306 p. 111 illus., 38 illus. in color., 1 Paperback / softback
  • Ilmumisaeg: 12-Sep-2018
  • Kirjastus: Springer International Publishing AG
  • ISBN-10: 3319854402
  • ISBN-13: 9783319854403
It creates an awareness of the need to integrate clinical observations and neuroscientific theories if we want to progress further in clinical language research and patient care.

This book discusses theories that link functions to specific anatomical brain regions. The best known of these are the Broca and Wernicke regions, and these have become synonyms for the location of productive and receptive language functions respectively. This Broca-Wernicke model has proved to be such a powerful concept that is remains the predominant view in modern clinical practice. What is fascinating, however, is that there is little evidence for this strictly localist view on language functions. Modern neuroscience and numerous clinical observations in individual patients show that language functions are represented in complex and ever-changing neural networks. It is fair to say that the model is wrong, and that Broca’s and Wernicke’s areas in their classic forms do not exist.


This is a fascinating paradox: why do neurologists and neurosurgeons continue to use these iconic language models in everyday decision-making? In this book, the author uses his background as a neurosurgeon and a neuroscientist to provide some answers to this question. 


The book acquaints clinicians and researchers with the many different aspects of language representation in the brain. It provides a historical overview of functional localisation, as well as insights into the misjudgements that have kept the localist doctrine alive. It creates an awareness of the need to integrate clinical observations and neuroscientific theories if we want to progress further in clinical language research and patient care.

Arvustused

Geert-Jan Ruttens book The Broca-Wernicke Doctrine offers an extraordinary journey through language localization, symptomatology, and its history. After reading this book, the reader will have a broad panorama of language in neuroscience . A must read for each neurosurgeon interested in the field of aphasia and also in localization of brain function. (Adrien Thomas May and Karl Schaller, Acta Neurochirurgica, Vol. 160 (2), February, 2018)



Geert-Jan Rutten seeks to clarify historical and current concepts of how brain regions relate to language and other functions. The result is an entertaining and enlightening tour of the history of cerebral neuroscience. This book is clearly targeted to neurosurgeons and neuroscientists and includes an appropriate level of scientific detail, yet it is consistently engaging and easy to read with logical organization and excellent summaries. (Jonathan Miller, Neurosurgery, January, 2018)

1 Broca and the Birth of Localization Theories
1(22)
1.1 Gall
3(1)
1.2 Flourens
4(3)
1.3 Bouillaud and Broca
7(6)
1.4 Trousseau and Marie
13(1)
1.5 TheEraofCTandMRI
14(3)
1.6 From Single Words to Sentences
17(2)
References
19(4)
2 Wernicke and Connectionism
23(24)
2.1 Meynert
24(1)
2.2 The Symptom Complex of Aphasia, Part I
25(2)
2.3 The Symptom Complex of Aphasia, Part II
27(12)
2.3.1 Lesion of the Acoustic Nerve
28(1)
2.3.2 Lesion of the Auditory Memory Centre: `Wernicke's Aphasia'
29(6)
2.3.3 Lesion of Tract ab
35(3)
2.3.4 Lesion of Movement Centre b
38(1)
2.3.5 Lesion of the Efferent Tract b
38(1)
2.4 The Symptom Complex of Aphasia, Part III
39(4)
2.5 Wernicke and the Anatomy of Language Areas
43(2)
References
45(2)
3 Aphasia or Agnosia?
47(10)
3.1 Lissauer
48(3)
3.2 Freund
51(2)
3.3 A Systematic Approach to the Anomic Patient
53(1)
References
54(3)
4 The Diagram Makers and Their Critics
57(20)
4.1 Lichtheim
57(2)
4.2 Kussmaul
59(2)
4.3 Hughlings Jackson
61(6)
4.4 Freud
67(4)
4.5 Marie, Head and the Decline of Localism
71(3)
References
74(3)
5 Naming and Numbering the Convolutions
77(34)
5.1 Ecker, Leuret and Gratiolet: Order Out of Chaos
78(4)
5.2 Microscopic Cartography
82(13)
5.2.1 Brodmann
87(6)
5.2.2 Campbell
93(2)
5.3 Language Areas Defined in Terms of Gyri and Sulci
95(11)
5.3.1 Broca'sArea
97(3)
5.3.2 The Planum Temporale
100(6)
5.4 Some Concluding Remarks
106(1)
References
106(5)
6 Mapping and Lesioning the Living Brain
111(68)
6.1 Fritsch and Hitzig
111(4)
6.2 Ferrier
115(4)
6.3 Sherrington and Grunbaum: The Primate Motor Cortex
119(6)
6.4 Krause, Foerster and Penfield: The Human Motor Cortex
125(7)
6.5 Bartholow and Cushing: First Experiences from Conscious Patients
132(4)
6.6 Penfield's Speech and Brain Mechanisms
136(14)
6.7 Ojemann: Expanding the Language Territory
150(5)
6.8 Duffau: Subcortical Pathways and Hodology
155(8)
6.9 The Wada Test and Electrical Stimulation Mapping: Gold Standards by Default
163(9)
6.9.1 Language Dominance
163(4)
6.9.2 Wada Test
167(1)
6.9.3 Electrocortical Stimulation Mapping
168(4)
References
172(7)
7 Neo-connectionism, Neurodynamics and Large-Scale Networks
179(52)
7.1 Geschwind
179(8)
7.1.1 Neo-connectionism
184(3)
7.2 Luria
187(11)
7.2.1 Functional Systems
189(3)
7.2.2 Aphasia
192(6)
7.3 Computational Models and Parallel Processing
198(3)
7.4 Language and Evolution
201(12)
7.4.1 Homologue Language Areas in Non-human Primates
206(7)
7.5 Mesulam, Hickok and Poeppel
213(11)
7.5.1 Epicentres
216(3)
7.5.2 Dual-Stream Models
219(3)
7.5.3 Phonological Loop
222(2)
References
224(7)
8 Functional MRI
231(38)
8.1 Brief Introduction to the Method
231(5)
8.1.1 Task Conditions
232(3)
8.1.2 Detection Power
235(1)
8.2 Historical Perspective
236(4)
8.3 What Neuroscientific Studies Taught Us About the Neural Basis of Language
240(11)
8.3.1 Some Landmark Studies
240(6)
8.3.2 From Single Words to Sentences
246(2)
8.3.3 A New Anatomical-Functional Perspective
248(3)
8.4 What fMRI Can Contribute to Clinical Care
251(12)
8.4.1 From Significance to Relevance
252(1)
8.4.2 Some Remarks About the Reliability and Spatial Precision of Brain Maps
253(4)
8.4.3 Language Laterality and Language Dominance
257(2)
8.4.4 Involved and Critical Language Areas
259(2)
8.4.5 How to Move Further
261(2)
References
263(6)
9 Recovery from Brain Damage
269(32)
9.1 Historical Perspective on Restoration of Function
269(11)
9.1.1 Momentum
269(1)
9.1.2 Age
270(2)
9.1.3 Experimental Studies in Animals
272(2)
9.1.4 General Observations on Brain-Injured Patients
274(4)
9.1.5 Mechanisms of Neural Plasticity
278(1)
9.1.6 Redundancy
279(1)
9.2 The Lateral Shift Hypothesis
280(11)
9.2.1 Broca
281(3)
9.2.2 The Confusing Results of Modern Imaging Methods
284(3)
9.2.3 Acute-Onset Lesions
287(2)
9.2.4 Lesions That Tend to Grow Slowly or Are Congenital
289(2)
9.3 The Efficacy of Aphasia Treatment
291(4)
9.3.1 Experience-Induced Plasticity
292(2)
9.3.2 Techniques to Enhance Plasticity
294(1)
References
295(6)
Epilogue 301(2)
Are There Any Language-Critical Cortical Areas? 303(2)
When Will Clinicians Put Aside the Classic Model? 305
Geert-Jan Rutten works as a neurosurgeon at the St Elisabeth-Tweesteden Hospital in Tilburg (the Netherlands), where he has a special interest in brain tumour surgery and functional brain mapping. He is also involved in research that focuses on the relationship between brain, cognition and behaviour in neurosurgical patients.