Praise for the Second Edition:… this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study....Loe edasi...
Cell and gene therapies have become the third major drug modality in pharmaceutical medicine of the 21st century after low molecular weight and antibody drugs. The gene therapy (GTx) field is rapidly advancing, and yet there are still fundamental sc...Loe edasi...
Bringing together leading statisticians, scientists, and clinicians from the pharmaceutical industry, academia, and regulatory agencies, this volume explores the rapidly growing area of multiple comparison research with an emphasis on pharmaceutic...Loe edasi...
Bayesian adaptive designs provide a critical approach to improve the efficiency and success rate of drug development that has been embraced by the US Food and Drug Administration (FDA). This is particularly important for early phase trials as they f...Loe edasi...
The book is designed to be accessible to readers with an intermediate knowledge of statistics, and can be a useful resource to statisticians, medical researchers, and regulatory personnel in drug development, as well as graduate students in the heal...Loe edasi...
The cost for bringing new medicine from discovery to market has nearly doubled in the last decade and has now reached 2.6 billion. There is an urgent need to make drug development less time-consuming and less costly. Innovative tri...Loe edasi...
The book is designed to be accessible to readers with an intermediate knowledge of statistics, and can be a useful resource to statisticians, medical researchers, and regulatory personnel in drug development, as well as graduate students in the heal...Loe edasi...
Praise for the Second Edition:… this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study....Loe edasi...
Statistical methods that are commonly used in the review and approval process of regulatory submissions are usually referred to as statistics in regulatory science or regulatory statistics. In a broader sense, statistics in regulatory science can...Loe edasi...
The cost for bringing new medicine from discovery to market has nearly doubled in the last decade and has now reached 2.6 billion. There is an urgent need to make drug development less time-consuming and less costly. Innovative trial designs/anal...Loe edasi...
Since the publication of the first edition in 2000, there has been an explosive growth of literature in biopharmaceutical research and development of new medicines. This encyclopedia (1) provides a comprehensive and unified presentation of designs...Loe edasi...
Like the well-regarded and bestselling second edition, Sample Size Calculations in Clinical Research, Third Edition, presents statistical procedures for performing sample size calculations during various phases of clinical research and development. T...Loe edasi...
(Ilmumisaeg: 18-Feb-2014, Hardback, Kirjastus: John Wiley & Sons Inc, ISBN-13: 9781118152126)
This volume demonstrates how to use chromatography to measure the physicochemical and biomimetic properties of drug absorption and distribution in vivo for drug candidates in the early stages of drug discovery. It explains the drug discovery process;...Loe edasi...
In recent years, the variations of pharmaceutical products in efficacy and safety among different geographic regions due to ethic factors is a matter of great concern for sponsors as well as for regulatory authorities. However, the key issues lie on...Loe edasi...
Editors Cosmatos (early development and clinical pharmacology, Wyeth Research) and Chow (biostatistics and bioinformatics, Duke U. School of Medicine) use contributions from experts all over the world to explore the emerging field of translational me...Loe edasi...
saadame teile pakkumise kasutatud raamatule, mille hind võib erineda kodulehel olevast hinnast
Senn (statistics, U. of Glasgow, UK) discusses the statistical issues related to drug development, presenting them in a way that life scientists working in the field can understand. First covering historical, philosophical, technical, and professiona...Loe edasi...
saadame teile pakkumise kasutatud raamatule, mille hind võib erineda kodulehel olevast hinnast
Focusing on an integral part of pharmaceutical development, Sample Size Calculations in Clinical Research, Second Edition presents statistical procedures for performing sample size calculations during various phases of clinical research and developme...Loe edasi...
Alex Dmitrienko, Christy Chuang-Stein, Ralph D'Agostino
Sari: SAS Press
(Ilmumisaeg: 07-Feb-2007, Paperback / softback, Kirjastus: SAS Institute, ISBN-13: 9781590478868)
This volume covers statistical methods used in drug discovery, animal toxicology studies, and clinical trials, for use by biostatisticians, pharmaceutical researchers, regulatory scientists, academic researchers, and graduate students. The 14 chapter...Loe edasi...
