Muutke küpsiste eelistusi

Cluster and Classification Techniques for the Biosciences [Kõva köide]

(Manchester Metropolitan University)
  • Formaat: Hardback, 258 pages, kõrgus x laius x paksus: 253x180x17 mm, kaal: 683 g, 58 Tables, unspecified; 62 Line drawings, unspecified
  • Ilmumisaeg: 14-Dec-2006
  • Kirjastus: Cambridge University Press
  • ISBN-10: 0521852811
  • ISBN-13: 9780521852814
Teised raamatud teemal:
  • Formaat: Hardback, 258 pages, kõrgus x laius x paksus: 253x180x17 mm, kaal: 683 g, 58 Tables, unspecified; 62 Line drawings, unspecified
  • Ilmumisaeg: 14-Dec-2006
  • Kirjastus: Cambridge University Press
  • ISBN-10: 0521852811
  • ISBN-13: 9780521852814
Teised raamatud teemal:
Guide to use of clustering and classification statistical methods for biologists, from ecologists to bioinformaticians.

Recent advances in experimental methods have resulted in the generation of enormous volumes of data across the life sciences. Hence clustering and classification techniques that were once predominantly the domain of ecologists are now being used more widely. This book provides an overview of these important data analysis methods, from long-established statistical methods to more recent machine learning techniques. It aims to provide a framework that will enable the reader to recognise the assumptions and constraints that are implicit in all such techniques. Important generic issues are discussed first and then the major families of algorithms are described. Throughout the focus is on explanation and understanding and readers are directed to other resources that provide additional mathematical rigour when it is required. Examples taken from across the whole of biology, including bioinformatics, are provided throughout the book to illustrate the key concepts and each technique's potential.

Arvustused

"...the book contains quite a lot of useful material for those embarking in this area...." - Morven Leese, Biometrics

Muu info

A 2006 guide to use of clustering and classification statistical methods for biologists, from ecologists to bioinformaticians.
Preface xi
Introduction
1(11)
Background
1(1)
Book structure
2(1)
Classification
2(1)
Clustering
3(1)
Structures in data
3(2)
Glossary
5(5)
Recommended reading and other resources
10(2)
Exploratory data analysis
12(34)
Background
12(1)
Dimensionality
13(1)
Goodness of fit testing
14(1)
Graphical methods
15(1)
Variance-based data projections
16(13)
Distance-based data projections
29(3)
Other projection methods
32(4)
Other methods
36(2)
Data dredging
38(1)
Example EDA analysis
38(8)
Cluster analysis
46(32)
Background
46(2)
Distance and similarity measures
48(7)
Partitioning methods
55(3)
Agglomerative hierarchical methods
58(4)
How many groups are there?
62(3)
Divisive hierarchical methods
65(1)
Two-way clustering and gene shaving
66(1)
Recommended reading
67(1)
Example analyses
68(10)
Introduction to classification
78(19)
Background
78(3)
Black-box classifiers
81(1)
Nature of a classifier
82(3)
No-free-lunch
85(1)
Bias and variance
86(1)
Variable (feature) selection
87(5)
Multiple classifiers
92(2)
Why do classifiers fail?
94(1)
Generalisation
95(1)
Types of classifier
96(1)
Classification algorithms 1
97(40)
Background
97(2)
Naive Bayes
99(1)
Discriminant analysis
100(17)
Logistic regression
117(11)
Discriminant analysis or logistic regression?
128(2)
Generalised additive models
130(6)
Summary
136(1)
Other classification methods
137(42)
Background
137(1)
Decision trees
137(17)
Support vector machines
154(2)
Artificial neural networks
156(14)
Genetic algorithms
170(5)
Others
175(2)
Where next?
177(2)
Classification accuracy
179(21)
Background
179(1)
Appropriate metrics
180(1)
Binary accuracy measures
180(3)
Appropriate testing data
183(3)
Decision thresholds
186(1)
Example
187(3)
ROC plots
190(4)
Incorporating costs
194(2)
Comparing classifiers
196(3)
Recommended reading
199(1)
Appendix A 200(3)
Appendix B 203(4)
Appendix C 207(1)
Appendix D 208(2)
Appendix E 210(7)
Appendix F 217(3)
Appendix G 220(4)
References 224(17)
Index 241


Alan H. Fielding is Senior Lecturer in the Division of Biology at Manchester Metropolitan University.